4CD8

The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManMIm

Summary for 4CD8

Entry DOI	10.2210/pdb4cd8/pdb
Related	4CD4 4CD5 4CD6 4CD7
Descriptor	ENDO-BETA-1,4-MANNANASE, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, beta-D-mannopyranose, ... (4 entities in total)
Functional Keywords	hydrolase, beta-mannosidase, mannosidase, glycoside hydrolase, gh26, gh113, cazy, enzyme-carbohydrate interaction, glycosidase inhibition, quantum mechanics, biocatalysis, conformation
Biological source	ALICYCLOBACILLUS ACIDOCALDARIUS
Total number of polymer chains	1
Total formula weight	36723.31
Authors	Williams, R.J.,Iglesias-Fernandez, J.,Stepper, J.,Jackson, A.,Thompson, A.J.,Lowe, E.C.,White, J.M.,Gilbert, H.J.,Rovira, C.,Davies, G.J.,Williams, S.J. (deposition date: 2013-10-30, release date: 2014-04-02, Last modification date: 2023-12-20)
Primary citation	Williams, R.J.,Iglesias-Fernandez, J.,Stepper, J.,Jackson, A.,Thompson, A.J.,Lowe, E.C.,White, J.M.,Gilbert, H.J.,Rovira, C.,Davies, G.J.,Williams, S.J. Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate. Angew.Chem.Int.Ed.Engl., 53:1087-, 2014 Cited by PubMed: 24339341 DOI: 10.1002/ANIE.201308334 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.47 Å)

Structure validation