5ISC
| Crystal structure of mouse CARM1 in complex with inhibitor SA0491 | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with inhibitor SA0491 To Be Published
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6X66
| Legionella pneumophila dDot T4SS OMC | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | 登録日 | 2020-05-27 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
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8PIV
| Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 1 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Glutamate receptor, ... | 著者 | Zhang, D, Krieger, J.M, Yamashita, K, Greger, I.H. | 登録日 | 2023-06-22 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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6XGQ
| YSD1 bacteriophage capsid | 分子名称: | YSD1_16, YSD1_17 | 著者 | Hardy, J.M, Dunstan, R, Venugopal, H, Lithgow, T.J, Coulibaly, F.J. | 登録日 | 2020-06-17 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The architecture and stabilisation of flagellotropic tailed bacteriophages. Nat Commun, 11, 2020
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5IS7
| Crystal structure of mouse CARM1 in complex with decarboxylated SAH | 分子名称: | 1,2-ETHANEDIOL, 5'-S-(3-aminopropyl)-5'-thioadenosine, DI(HYDROXYETHYL)ETHER, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with decarboxylated SAH To Be Published
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5ISI
| Crystal structure of mouse CARM1 in complex with inhibitor SA0920 (5'-amino-5'-deoxyadenosine) | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 5'-amino-5'-deoxyadenosine, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with inhibitor SA0920 (5'-amino-5'-deoxyadenosine) To Be Published
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8PHY
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8PYI
| Human IGF1R with inhibitor 6 | 分子名称: | 3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol, Insulin-like growth factor 1 receptor beta chain | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Human IGF1R with inhibitor 6 To Be Published
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5I80
| BRD4 in complex with Cpd2 (N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide) | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, ... | 著者 | Murray, J.M. | 登録日 | 2016-02-18 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.4501 Å) | 主引用文献 | Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. J.Med.Chem., 59, 2016
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8PYJ
| Human IGF1R with inhibitor 8 | 分子名称: | 5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Human IGF1R with inhibitor 8 To Be Published
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8PYK
| Human IGF1R with inhibitor 47 | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, Insulin-like growth factor 1 receptor beta chain, NICKEL (II) ION | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Human IGF1R with inhibitor 47 To Be Published
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8Q6J
| Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, Pertuzumab Fab light chain, ... | 著者 | Ruedas, R, Vuillemot, R, Tubiana, T, Winter, J.M, Pieri, L, Arteni, A.A, Samson, C, Jonic, J, Mathieu, M, Bressanelli, S. | 登録日 | 2023-08-11 | 公開日 | 2023-09-20 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex. J.Struct.Biol., 216, 2024
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8PYL
| Human IGF1R with inhibitor 53 | 分子名称: | (5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Human IGF1R with inhibitor 53 To Be Published
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7NHP
| Structure of PSII-I (PSII with Psb27, Psb28, and Psb34) | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ... | 著者 | Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M. | 登録日 | 2021-02-11 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Structural insights into photosystem II assembly. Nat.Plants, 7, 2021
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7NHO
| Structure of PSII-M | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ... | 著者 | Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M. | 登録日 | 2021-02-11 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural insights into photosystem II assembly. Nat.Plants, 7, 2021
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8PYN
| Human IGF1R with inhibitor 56 | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Human IGF1R with inhibitor 56 To Be Published
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6XD3
| Structure of the human CAK in complex with THZ1 | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E. | 登録日 | 2020-06-09 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The cryoelectron microscopy structure of the human CDK-activating kinase. Proc.Natl.Acad.Sci.USA, 117, 2020
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8PYM
| Human IGF1R with inhibitor 54 | 分子名称: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ... | 著者 | Dreyer, M.K, Wang, J, Elkins, J.M. | 登録日 | 2023-07-25 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.652 Å) | 主引用文献 | Human IGF1R with inhibitor 54 To Be Published
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6X62
| Legionella pneumophila Dot T4SS OMC | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | 登録日 | 2020-05-27 | 公開日 | 2020-09-30 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
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6X65
| Legionella pneumophila Dot/Icm T4SS | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | 登録日 | 2020-05-27 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
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7N06
| SARS-CoV-2 Nsp15 endoribonuclease post-cleavage state | 分子名称: | RNA (5'-R(*AP*UP*A)-3'), Uridylate-specific endoribonuclease | 著者 | Frazier, M.N, Dillard, L.B, Krahn, J.M, Stanley, R.E. | 登録日 | 2021-05-25 | 公開日 | 2021-06-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U. Nucleic Acids Res., 49, 2021
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7NHQ
| Structure of PSII-I prime (PSII with Psb28, and Psb34) | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ... | 著者 | Zabret, J, Bohn, S, Schuller, S.K, Arnolds, O, Chan, A, Tajkhorshid, E, Stoll, R, Engel, B.D, Rudack, T, Schuller, J.M, Nowaczyk, M.M. | 登録日 | 2021-02-11 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Structural insights into photosystem II assembly. Nat.Plants, 7, 2021
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7NPC
| ROR(gamma)t ligand binding domain in complex with allosteric ligand FM156 | 分子名称: | 4-[[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrrol-3-yl)-1,2-oxazol-4-yl]methoxy]benzoic acid, GLYCEROL, Nuclear receptor ROR-gamma | 著者 | de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | 登録日 | 2021-02-26 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. J.Med.Chem., 64, 2021
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7NCS
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7NEC
| ROR(gamma)t ligand binding domain in complex with allosteric ligand FM217 | 分子名称: | 4-[[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrrol-2-yl)-1,2-oxazol-4-yl]methoxy]benzoic acid, Nuclear receptor ROR-gamma | 著者 | Somsen, B.A, de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | 登録日 | 2021-02-03 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. J.Med.Chem., 64, 2021
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