4C27
 
 | | Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-2-fluoro-4-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)benzamide | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Nalpha-(2-fluoro-4-{4-[4-(trifluoromethyl)phenyl]piperazin-1-yl}benzoyl)-N-pyridin-4-yl-D-tryptophanamide, ... | | 著者 | Vieira, D.F, Calvet, C.M, Choi, J.Y, Cameron, M.D, Gut, J, Kellar, D, Siqueira-Neto, J.L, McKerrow, J.H, Roush, W.R, Podust, L.M. | | 登録日 | 2013-08-16 | | 公開日 | 2014-09-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Binding Mode and Potency of N-Indolyl-Oxopyridinyl-4-Amino-Propanyl-Based Inhibitors Targeting Trypanosoma Cruzi Cyp51
J.Med.Chem., 57, 2014
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5GKC
 | | The crystal structure of the CPS-6 H148A/F122A | | 分子名称: | Endonuclease G, mitochondrial | | 著者 | Lin, J.L, Yuan, H.S. | | 登録日 | 2016-07-04 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | | 主引用文献 | Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
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3KQO
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3KR1
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6WYE
 | | Crystal structure of Neisseria gonorrhoeae serine acetyltransferase (CysE) | | 分子名称: | (2S)-2-hydroxybutanedioic acid, SODIUM ION, Serine acetyltransferase | | 著者 | Hicks, J.L, Oldham, K.E, Summers, E.L, Prentice, E.J. | | 登録日 | 2020-05-12 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Serine acetyltransferase from Neisseria gonorrhoeae; structural and biochemical basis of inhibition.
Biochem.J., 479, 2022
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5TZ7
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4IZ8
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS H8E at cryogenic temperature | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Bell-Upp, P.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | | 登録日 | 2013-01-29 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of Staphylococcal nuclease variant Delta+PHS H8E at cryogenic temperature
To be Published
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4MPE
 | | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS8 | | 分子名称: | 4-[(5-hydroxy-1,3-dihydro-2H-isoindol-2-yl)sulfonyl]benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... | | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. | | 登録日 | 2013-09-12 | | 公開日 | 2014-01-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.953 Å) | | 主引用文献 | Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
J.Biol.Chem., 289, 2014
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4J1M
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4C1S
 | | Glycoside hydrolase family 76 (mannosidase) Bt3792 from Bacteroides thetaiotaomicron VPI-5482 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, GLYCOSIDE HYDROLASE FAMILY 76 MANNOSIDASE | | 著者 | Cuskin, F, Lowe, E.C, Zhu, Y, Temple, M, Thompson, A.J, Cartmell, A, Piens, K, Bracke, D, Vervecken, W, Munoz-Munoz, J.L, Suits, M.D.L, Boraston, A.B, Williams, S.J, Davies, G.J, Abbott, W.D, Martens, E.C, Gilbert, H.J. | | 登録日 | 2013-08-13 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Human Gut Bacteroidetes Can Utilize Yeast Mannan Through a Selfish Mechanism.
Nature, 517, 2015
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6WW6
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4CCT
 | | Dengue 1 cryo-EM reconstruction | | 分子名称: | DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 M PROTEIN | | 著者 | Kostyuchenko, V.A, Zhang, Q, Tan, J.L, Ng, T.S, Lok, S.M. | | 登録日 | 2013-10-28 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process.
J.Virol., 87, 2013
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4J2I
 | | Multiple crystal structures of an all-AT DNA dodecamer stabilized by weak interactions | | 分子名称: | 5'-D(*AP*AP*TP*AP*AP*AP*TP*TP*TP*AP*TP*T)-3' | | 著者 | Acosta-Reyes, F.J, Subirana, J.A, Pous, J, Sanchez, R, Condom, N, Baldini, R, Malinina, L, Campos, J.L. | | 登録日 | 2013-02-04 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Polymorphic crystal structures of an all-AT DNA dodecamer.
Biopolymers, 103, 2015
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5GAR
 | | Thermus thermophilus V/A-ATPase, conformation 1 | | 分子名称: | Archaeal/vacuolar-type H+-ATPase subunit I, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | | 著者 | Schep, D.G, Zhao, J, Rubinstein, J.L. | | 登録日 | 2016-02-05 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | | 主引用文献 | Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4ISV
 | | Crystal structure of the Fab FRAGMENT OF 1C2, A MONOCLONAL ANTIBODY SPECIFIC FOR POLY-GLUTAMINE | | 分子名称: | 1C2 FAB HEAVY CHAIN, 1C2 FAB LIGHT CHAIN | | 著者 | Klein, F.A.C, Zeder-Lutz, G, Cousido-Siah, A, Mitschler, A, Katz, A, Eberling, P, Mandel, J.L, Podjarny, A, Trottier, Y. | | 登録日 | 2013-01-17 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | | 主引用文献 | Linear and extended: a common polyglutamine conformation recognized by the three antibodies MW1, 1C2 and 3B5H10.
Hum.Mol.Genet., 22, 2013
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5TZ6
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4C2I
 | | Cryo-EM structure of Dengue virus serotype 1 complexed with Fab fragments of human antibody 1F4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Fibriansah, G, Tan, J.L, de Alwis, R, Smith, S.A, Ng, T.-S, Kostyuchenko, V.A, Ibarra, K.D, Harris, E, de Silva, A, Crowe Junior, J.E, Lok, S.-M. | | 登録日 | 2013-08-18 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | A Potent Anti-Dengue Human Antibody Preferentially Recognizes the Conformation of E Protein Monomers Assembled on the Virus Surface.
Embo Mol.Med., 6, 2014
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4MIU
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4BV8
 | | Crystal structure of the apo form of mouse Mu-crystallin. | | 分子名称: | GLYCEROL, POTASSIUM ION, THIOMORPHOLINE-CARBOXYLATE DEHYDROGENASE | | 著者 | Borel, F, Hachi, I, Palencia, A, Gaillard, M.C, Ferrer, J.L. | | 登録日 | 2013-06-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Mouse Mu-Crystallin Complexed with Nadph and the T3 Thyroid Hormone
FEBS J., 281, 2014
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6XH3
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4MPC
 | | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS2 | | 分子名称: | 4-(isoindolin-2-ylsulfonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... | | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. | | 登録日 | 2013-09-12 | | 公開日 | 2014-01-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket.
J.Biol.Chem., 289, 2014
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7OXE
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5TRF
 | | MDM2 in complex with SAR405838 | | 分子名称: | (2'S,3R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide, E3 ubiquitin-protein ligase Mdm2, GLYCEROL, ... | | 著者 | Meagher, J.L, Stuckey, J.A. | | 登録日 | 2016-10-26 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression.
Cancer Res., 74, 2014
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5U3E
 | | Crystal Structure of Native Lectin from Canavalia bonariensis Seeds (CaBo) complexed with alpha-methyl-D-mannoside | | 分子名称: | CALCIUM ION, Canavalia bonariensis seed lectin, MANGANESE (II) ION, ... | | 著者 | Silva, M.T.L, Osterne, V.J.S, Pinto-Junior, V.R, Santiago, M.Q, Araripe, D.A, Neco, A.H.B, Silva-Filho, J.C, Martins, J.L, Rocha, C.R.C, Leal, R.B, Nascimento, K.S, Cavada, B.S. | | 登録日 | 2016-12-02 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Canavalia bonariensis lectin: Molecular bases of glycoconjugates interaction and antiglioma potential.
Int. J. Biol. Macromol., 106, 2018
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8EGS
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