2YPG
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![BU of 2ypg by Molmil](/molmil-images/mine/2ypg) | Haemagglutinin of 1968 Human H3N2 Virus in Complex with Human Receptor Analogue LSTc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, J, Xiong, X, Haire, L.F, Lin, Y.P, Wharton, S.A, Martin, S.R, Coombs, P.J, Vachieri, S.G, Christodoulou, E, Walker, P.A, Skehel, J.J, Gamblin, S.J, Hay, A.J, Daniels, R.S, McCauley, J.W. | Deposit date: | 2012-10-30 | Release date: | 2012-11-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin. Proc.Natl.Acad.Sci.USA, 109, 2012
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6C5X
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![BU of 6c5x by Molmil](/molmil-images/mine/6c5x) | Crystal Structure of SOCS1 in complex with ElonginB and ElonginC | Descriptor: | Elongin-B, Elongin-C, GP130 peptide fragment, ... | Authors: | Kershaw, N.J, Laktyushin, A, Babon, J.J. | Deposit date: | 2018-01-17 | Release date: | 2018-05-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.105 Å) | Cite: | The molecular basis of JAK/STAT inhibition by SOCS1. Nat Commun, 9, 2018
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5JCD
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![BU of 5jcd by Molmil](/molmil-images/mine/5jcd) | Crystal structure of OsCEBiP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor-binding protein | Authors: | Chai, J.J, Liu, S.M, Wang, J.Z. | Deposit date: | 2016-04-15 | Release date: | 2017-02-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular Mechanism for Fungal Cell Wall Recognition by Rice Chitin Receptor OsCEBiP Structure, 24, 2016
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6C7S
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![BU of 6c7s by Molmil](/molmil-images/mine/6c7s) | Structure of Rifampicin Monooxygenase with Product Bound | Descriptor: | (1E,3S,4R,5S,6R,7R,8R,9S,10S,11E,13E)-15-amino-1-{[(2S)-5,7-dihydroxy-2,4-dimethyl-8-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-1,6,9-trioxo-1,2,6,9-tetrahydronaphtho[2,1-b]furan-2-yl]oxy}-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxopentadeca-1,11,13-trien-5-yl acetate, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Liu, L.-K, Tanner, J.J. | Deposit date: | 2018-01-23 | Release date: | 2018-04-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Evidence for Rifampicin Monooxygenase Inactivating Rifampicin by Cleaving Its Ansa-Bridge. Biochemistry, 57, 2018
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6C7Y
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![BU of 6c7y by Molmil](/molmil-images/mine/6c7y) | Crystal structure of inhibitory protein SOCS1 in complex with JAK1 kinase domain | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Liau, N.P.D, Laktyushin, A, Lucet, I.S, Murphy, J.M, Yao, S, Callaghan, K, Nicola, N.A, Kershaw, N.J, Babon, J.J. | Deposit date: | 2018-01-23 | Release date: | 2018-05-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | The molecular basis of JAK/STAT inhibition by SOCS1. Nat Commun, 9, 2018
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2BJN
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![BU of 2bjn by Molmil](/molmil-images/mine/2bjn) | X-ray Structure of human TPC6 | Descriptor: | GLYCEROL, SULFATE ION, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B | Authors: | Kummel, D, Mueller, J.J, Roske, Y, Misselwitz, R, Bussow, K, Heinemann, U. | Deposit date: | 2005-02-04 | Release date: | 2005-07-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structure of the Trapp Subunit Tpc6 Suggests a Model for a Trapp Subcomplex. Embo Rep., 6, 2005
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2Y9W
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![BU of 2y9w by Molmil](/molmil-images/mine/2y9w) | Crystal structure of PPO3, a tyrosinase from Agaricus bisporus, in deoxy-form that contains additional unknown lectin-like subunit | Descriptor: | COPPER (II) ION, DI(HYDROXYETHYL)ETHER, HOLMIUM ATOM, ... | Authors: | Ismaya, W.T, Rozeboom, H.J, Weijn, A, Mes, J.J, Fusetti, F, Wichers, H.J, Dijkstra, B.W. | Deposit date: | 2011-02-17 | Release date: | 2011-07-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Agaricus Bisporus Mushroom Tyrosinase: Identity of the Tetramer Subunits and Interaction with Tropolone. Biochemistry, 50, 2011
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2YP3
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![BU of 2yp3 by Molmil](/molmil-images/mine/2yp3) | Haemagglutinin of 2004 Human H3N2 Virus in Complex with Human Receptor Analogue 6SLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Xiong, X, Lin, Y.P, Wharton, S.A, Martin, S.R, Coombs, P.J, Vachieri, S.G, Christodoulou, E, Walker, P.A, Liu, J, Skehel, J.J, Gamblin, S.J, Hay, A.J, Daniels, R.S, McCauley, J.W. | Deposit date: | 2012-10-29 | Release date: | 2012-11-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin. Proc.Natl.Acad.Sci.USA, 109, 2012
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5JJG
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![BU of 5jjg by Molmil](/molmil-images/mine/5jjg) | Structure of magnesium-loaded ALG-2 | Descriptor: | ISOPROPYL ALCOHOL, MAGNESIUM ION, Pcalcium-binding protein ALG-2, ... | Authors: | Tanner, J.J. | Deposit date: | 2016-04-23 | Release date: | 2016-09-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | EF5 Is the High-Affinity Mg(2+) Site in ALG-2. Biochemistry, 55, 2016
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5IZP
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![BU of 5izp by Molmil](/molmil-images/mine/5izp) | Solution Structure of DNA Dodecamer with 8-oxoguanine at 10th Position | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*(8OG)P*CP*G)-3') | Authors: | Gruber, D.R, Hoppins, J.J, Miears, H.L, Kiryutin, A.S, Kasymov, R.D, Yurkovskaya, A.V, Zharkov, D.O, Smirnov, S.L. | Deposit date: | 2016-03-25 | Release date: | 2016-08-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | 8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and Inhibits Its Cleavage by the Enzyme. Plos One, 11, 2016
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2VBK
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![BU of 2vbk by Molmil](/molmil-images/mine/2vbk) | NATIVE TAILSPIKE PROTEIN OF BACTERIOPHAGE SF6 | Descriptor: | 1,2-ETHANEDIOL, CARBON DIOXIDE, GLYCEROL, ... | Authors: | Mueller, J.J, Barbirz, S, Heinle, K, Freiberg, A, Seckler, R, Heinemann, U. | Deposit date: | 2007-09-14 | Release date: | 2008-04-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6. Structure, 16, 2008
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5JYN
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![BU of 5jyn by Molmil](/molmil-images/mine/5jyn) | Structure of the transmembrane domain of HIV-1 gp41 in bicelle | Descriptor: | Envelope glycoprotein gp160 | Authors: | Dev, J, Fu, Q, Park, D, Chen, B, Chou, J.J. | Deposit date: | 2016-05-14 | Release date: | 2016-06-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis for membrane anchoring of HIV-1 envelope spike. Science, 353, 2016
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5JW5
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![BU of 5jw5 by Molmil](/molmil-images/mine/5jw5) | Structure of MEDI8852 Fab Fragment | Descriptor: | MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION | Authors: | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2016-05-11 | Release date: | 2016-08-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
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2ZFC
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![BU of 2zfc by Molmil](/molmil-images/mine/2zfc) | X-ray crystal structure of an engineered N-terminal HIV-1 GP41 trimer with enhanced stability and potency | Descriptor: | HIV-1 GP41 | Authors: | Dwyer, J.J, Wilson, K.L, Martin, K, Seedorff, J.E, Hasan, A, Kim, H. | Deposit date: | 2007-12-29 | Release date: | 2008-04-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potency Protein Sci., 17, 2008
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5IAS
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![BU of 5ias by Molmil](/molmil-images/mine/5ias) | Caspase 3 V266Y | Descriptor: | ACE-ASP-GLU-VAL-ASK, Caspase-3, SODIUM ION | Authors: | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | Deposit date: | 2016-02-21 | Release date: | 2016-10-26 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
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2ZIU
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![BU of 2ziu by Molmil](/molmil-images/mine/2ziu) | Crystal structure of the Mus81-Eme1 complex | Descriptor: | Crossover junction endonuclease EME1, Mus81 protein | Authors: | Chang, J.H, Kim, J.J, Choi, J.M, Lee, J.H, Cho, Y. | Deposit date: | 2008-02-25 | Release date: | 2008-04-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Mus81-Eme1 complex Genes Dev., 22, 2008
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1EO8
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![BU of 1eo8 by Molmil](/molmil-images/mine/1eo8) | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ... | Authors: | Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T. | Deposit date: | 2000-03-22 | Release date: | 2000-04-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural evidence for recognition of a single epitope by two distinct antibodies. Proteins, 40, 2000
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1KEO
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![BU of 1keo by Molmil](/molmil-images/mine/1keo) | TWISTS AND TURNS OF THE CD-MPR: LIGAND-BOUND VERSUS LIGAND-FREE RECEPTOR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, cation-dependent mannose-6-phosphate receptor | Authors: | Olson, L.J, Zhang, J, Dahms, N.M, Kim, J.J. | Deposit date: | 2001-11-16 | Release date: | 2002-01-23 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor J.Biol.Chem., 277, 2002
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2B3B
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![BU of 2b3b by Molmil](/molmil-images/mine/2b3b) | Thermus thermophilus Glucose/Galactose Binding Protein With Bound Glucose | Descriptor: | alpha-D-glucopyranose, beta-D-glucopyranose, glucose-binding protein | Authors: | Cuneo, M.J, Changela, A, Warren, J.J, Beese, L.S, Hellinga, H.W. | Deposit date: | 2005-09-20 | Release date: | 2006-07-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. J.Mol.Biol., 362, 2006
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6GCI
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![BU of 6gci by Molmil](/molmil-images/mine/6gci) | Structure of the bongkrekic acid-inhibited mitochondrial ADP/ATP carrier | Descriptor: | Bongkrekic acid, CARDIOLIPIN, HEXAETHYLENE GLYCOL, ... | Authors: | Ruprecht, J.J, King, M.S, Pardon, E, Aleksandrova, A.A, Zogg, T, Crichton, P.G, Steyaert, J, Kunji, E.R.S. | Deposit date: | 2018-04-17 | Release date: | 2019-01-09 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier. Cell, 176, 2019
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6BSN
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![BU of 6bsn by Molmil](/molmil-images/mine/6bsn) | |
3AVH
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![BU of 3avh by Molmil](/molmil-images/mine/3avh) | Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site | Descriptor: | ACETIC ACID, CHLORIDE ION, Integrase, ... | Authors: | Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. | Deposit date: | 2011-03-05 | Release date: | 2012-01-18 | Last modified: | 2013-06-19 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
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3AVL
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![BU of 3avl by Molmil](/molmil-images/mine/3avl) | Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site | Descriptor: | ACETIC ACID, CHLORIDE ION, Integrase, ... | Authors: | Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. | Deposit date: | 2011-03-05 | Release date: | 2012-01-18 | Last modified: | 2013-06-19 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
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6E0M
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![BU of 6e0m by Molmil](/molmil-images/mine/6e0m) | Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase | Descriptor: | DIPHOSPHATE, cGAS/DncV-like nucleotidyltransferase in E. coli homolog | Authors: | Eaglesham, J.B, Whiteley, A.T, de Oliveira Mann, C.C, Morehouse, B.R, Nieminen, E.A, King, D.S, Lee, A.S.Y, Mekalanos, J.J, Kranzusch, P.J. | Deposit date: | 2018-07-06 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567, 2019
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3AV9
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![BU of 3av9 by Molmil](/molmil-images/mine/3av9) | Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site | Descriptor: | ACETIC ACID, CHLORIDE ION, Integrase, ... | Authors: | Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. | Deposit date: | 2011-03-02 | Release date: | 2012-01-18 | Last modified: | 2013-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
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