5IZP

Solution Structure of DNA Dodecamer with 8-oxoguanine at 10th Position

Summary for 5IZP

• Entry DOI: 10.2210/pdb5izp/pdb
• Related: 5IV1
• NMR Information: BMRB: 30044
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*(8OG)P*CP*G)-3') (1 entity in total)
• Functional Keywords: drew-dickerson, dna, dodecamer, non-canonical, modified dna, oxidized dna, dna damage, dna adduct, lesion
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 7358.78

Authors

Gruber, D.R.,Hoppins, J.J.,Miears, H.L.,Kiryutin, A.S.,Kasymov, R.D.,Yurkovskaya, A.V.,Zharkov, D.O.,Smirnov, S.L. (deposition date: 2016-03-25, release date: 2016-08-03, Last modification date: 2016-10-26)

• Primary citation: Hoppins, J.J.,Gruber, D.R.,Miears, H.L.,Kiryutin, A.S.,Kasymov, R.D.,Petrova, D.V.,Endutkin, A.V.,Popov, A.V.,Yurkovskaya, A.V.,Fedechkin, S.O.,Brockerman, J.A.,Zharkov, D.O.,Smirnov, S.L.; 8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and Inhibits Its Cleavage by the Enzyme.; Plos One, 11:e0164424-e0164424, 2016; PubMed: 27749894; DOI: 10.1371/journal.pone.0164424

Experimental method

SOLUTION NMR