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PDB: 2437 results
8EYC
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BU of 8eyc by Molmil
Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with TYK2 activation loop phosphopeptide
Descriptor: Non-receptor tyrosine-protein kinase TYK2 activation loop phosphopeptide, Tyrosine-protein phosphatase non-receptor type 1
Authors:Morris, R, Kershaw, N.J, Babon, J.J.
Deposit date:2022-10-26
Release date:2023-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structure guided studies of the interaction between PTP1B and JAK.
Commun Biol, 6, 2023
8FN4
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BU of 8fn4 by Molmil
Cryo-EM structure of RNase-treated RESC-A in trypanosomal RNA editing
Descriptor: RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), RNA-editing substrate-binding complex protein 3 (RESC3), ...
Authors:Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2022-12-26
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FN6
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BU of 8fn6 by Molmil
Cryo-EM structure of RNase-untreated RESC-A in trypanosomal RNA editing
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), ...
Authors:Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2022-12-27
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8T8K
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BU of 8t8k by Molmil
Structure of Domain of Unknown Function 507 (DUF507) in Space Group C222(1)
Descriptor: DUF507 family protein, HEXANE-1,6-DIOL
Authors:Tanner, J.J, McKay, C.E.
Deposit date:2023-06-22
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of domain of unknown function 507 (DUF507) reveals a new protein fold.
Sci Rep, 13, 2023
8FNC
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BU of 8fnc by Molmil
Cryo-EM structure of RNase-treated RESC-C in trypanosomal RNA editing
Descriptor: Mitochondrial RNA binding complex 1 subunit, Mitochondrial RNA binding protein, Phytanoyl-CoA dioxygenase family protein, ...
Authors:Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2022-12-27
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FNF
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BU of 8fnf by Molmil
Cryo-EM structure of RNase-untreated RESC-C in trypanosomal RNA editing
Descriptor: Mitochondrial RNA binding complex 1 subunit, Mitochondrial RNA binding protein, Phytanoyl-CoA dioxygenase family protein, ...
Authors:Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2022-12-27
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
4JNZ
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BU of 4jnz by Molmil
Crystal structure of PutA86-630 mutant D370N complexed with L-Tetrahydro-2-furoic acid
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ...
Authors:Tanner, J.J.
Deposit date:2013-03-16
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Involvement of the beta 3-alpha 3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A.
Biochemistry, 52, 2013
8FNI
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BU of 8fni by Molmil
Cryo-EM structure of RNase-treated RESC-B in trypanosomal RNA editing
Descriptor: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ...
Authors:Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2022-12-27
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8T8L
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BU of 8t8l by Molmil
Structure of Domain of Unknown Function 507 (DUF507) in Space Group P3(2)21
Descriptor: DI(HYDROXYETHYL)ETHER, DUF507 family protein, SODIUM ION
Authors:Tanner, J.J, McKay, C.E.
Deposit date:2023-06-22
Release date:2023-08-30
Method:SOLUTION SCATTERING (1.9 Å), X-RAY DIFFRACTION
Cite:Crystal structure of domain of unknown function 507 (DUF507) reveals a new protein fold.
Sci Rep, 13, 2023
8FNK
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BU of 8fnk by Molmil
Cryo-EM structure of RNase-untreated RESC-B in trypanosomal RNA editing
Descriptor: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ...
Authors:Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2022-12-27
Release date:2023-07-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
6WU1
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BU of 6wu1 by Molmil
Structure of apo LaINDY
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N.C, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
1SIR
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BU of 1sir by Molmil
The Crystal Structure and Mechanism of Human Glutaryl-CoA Dehydrogenase
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase, S-4-NITROBUTYRYL-COA
Authors:Wang, M, Fu, Z, Paschke, R, Goodman, S.L, Frerman, F.E, Kim, J.J.
Deposit date:2004-03-01
Release date:2004-09-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004
8T9X
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BU of 8t9x by Molmil
Zophobas morio black wasting virus strain NJ2-molitor virion structure
Descriptor: DNA (5'-D(P*CP*AP*GP*GP*CP*CP*AP*AP*A)-3'), DNA (5'-D(P*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*AP*A)-3'), ...
Authors:Penzes, J.J, Kaelber, J.T.
Deposit date:2023-06-26
Release date:2024-02-21
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Sequencing-free discovery by cryo-EM of a pathogenic parvovirus causing mass mortality of farmed beetles
To Be Published
8TA7
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BU of 8ta7 by Molmil
Zophobas morio black wasting virus strain OR-molitor empty capsid structure
Descriptor: Major capsid protein
Authors:Penzes, J.J, Kaelber, J.T.
Deposit date:2023-06-26
Release date:2023-08-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Sequencing-free discovery by cryo-EM of a pathogenic parvovirus causing mass mortality of farmed beetles
To Be Published
8T9E
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BU of 8t9e by Molmil
Zophobas morio black wasting virus strain UT-morio empty capsid structure
Descriptor: Major capsid protein
Authors:Penzes, J.J, Kaelber, J.T.
Deposit date:2023-06-23
Release date:2023-08-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Sequencing-free discovery by cryo-EM of a pathogenic parvovirus causing mass mortality of farmed beetles
To Be Published
8TTJ
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BU of 8ttj by Molmil
Tryptophan-6-halogenase BorH complexed with 6-chlorotryptophan
Descriptor: 6-CHLORO-L-TRYPTOPHAN, SULFATE ION, Tryptophan 6-halogenase
Authors:Lingkon, K, Bellizzi, J.J.
Deposit date:2023-08-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH.
Biorxiv, 2023
6X3Z
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BU of 6x3z by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ...
Authors:Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E.
Deposit date:2020-05-21
Release date:2020-09-09
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Shared structural mechanisms of general anaesthetics and benzodiazepines.
Nature, 585, 2020
8T9C
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BU of 8t9c by Molmil
Zophobas morio black wasting virus strain UT-morio virion structure
Descriptor: DNA (5'-D(P*CP*AP*GP*GP*CP*CP*AP*A)-3'), DNA (5'-D(P*CP*G)-3'), DNA (5'-D(P*CP*GP*A)-3'), ...
Authors:Penzes, J.J, Kaelber, J.T.
Deposit date:2023-06-23
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Sequencing-free discovery by cryo-EM of a pathogenic parvovirus causing mass mortality of farmed beetles
To Be Published
1SFP
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BU of 1sfp by Molmil
CRYSTAL STRUCTURE OF ACIDIC SEMINAL FLUID PROTEIN (ASFP) AT 1.9 A RESOLUTION: A BOVINE POLYPEPTIDE FROM THE SPERMADHESIN FAMILY
Descriptor: ASFP
Authors:Romao, M.J, Kolln, I, Dias, J.M, Carvalho, A.L, Romero, A, Varela, P.F, Sanz, L, Topfer-Petersen, E, Calvete, J.J.
Deposit date:1997-06-24
Release date:1998-06-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structures of two spermadhesins reveal the CUB domain fold.
Nat.Struct.Biol., 4, 1997
8TJE
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BU of 8tje by Molmil
Zophobas morio black wasting virus strain OR-molitor virion structure
Descriptor: DNA (5'-D(P*CP*AP*GP*GP*CP*CP*AP*AP*A)-3'), DNA (5'-D(P*CP*G)-3'), DNA (5'-D(P*TP*CP*GP*AP*A)-3'), ...
Authors:Penzes, J.J, Kaelber, J.T.
Deposit date:2023-07-20
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Sequencing-free discovery by cryo-EM of a pathogenic parvovirus causing mass mortality of farmed beetles
To Be Published
8TTI
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BU of 8tti by Molmil
Trp-6-Halogenase BorH complexed with FAD and Trp
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TRYPTOPHAN, ...
Authors:Lingkon, K, Bellizzi, J.J.
Deposit date:2023-08-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH.
Biorxiv, 2023
8TTK
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BU of 8ttk by Molmil
Tryptophan-6-halogenase BorH apo structure
Descriptor: SULFATE ION, Tryptophan 6-halogenase
Authors:Lingkon, K, Bellizzi, J.J.
Deposit date:2023-08-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystallographic and thermodynamic evidence of negative cooperativity of flavin and tryptophan binding in the flavin-dependent halogenases AbeH and BorH.
Biorxiv, 2023
6X3V
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BU of 6x3v by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus etomidate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Etomidate, ...
Authors:Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E.
Deposit date:2020-05-21
Release date:2020-09-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Shared structural mechanisms of general anaesthetics and benzodiazepines.
Nature, 585, 2020
6X0K
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BU of 6x0k by Molmil
Structure of dithionite-reduced SidA ornithine hydroxylase with the FAD "in" and complexed with L-ornithine
Descriptor: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-ornithine, L-ornithine N(5)-monooxygenase
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-05-15
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Trapping conformational states of a flavin-dependent N -monooxygenase in crystallo reveals protein and flavin dynamics.
J.Biol.Chem., 295, 2020
6X3T
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BU of 6x3t by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus propofol
Descriptor: 2,6-BIS(1-METHYLETHYL)PHENOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E.
Deposit date:2020-05-21
Release date:2020-09-09
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Shared structural mechanisms of general anaesthetics and benzodiazepines.
Nature, 585, 2020

226707

数据于2024-10-30公开中

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