4UV4
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![BU of 4uv4 by Molmil](/molmil-images/mine/4uv4) | Crystal structure of anti-FPR Fpro0165 Fab fragment | Descriptor: | FPRO0165 FAB | Authors: | Douthwaite, J.A, Sridharan, S, Huntington, C, Marwood, R, Hammersley, J, Hakulinen, J.K, Ek, M, Sjogren, T, Rider, D, Privezentzev, C, Seaman, J.C, Cariuk, P, Knights, V, Young, J, Wilkinson, T, Sleeman, M, Finch, D.K, Lowe, D.C, Vaughan, T.J. | Deposit date: | 2014-08-04 | Release date: | 2014-12-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1. Mabs, 7, 2015
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4UVE
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![BU of 4uve by Molmil](/molmil-images/mine/4uve) | Discovery of pyrimidine isoxazoles InhA in complex with compound 9 | Descriptor: | 2-(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYLETHANOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], MAGNESIUM ION, ... | Authors: | Read, J.A, Gingell, H, Madhavapeddi, P, Ghorpade, S, Cowan, S. | Deposit date: | 2014-08-05 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Hitting the Target in More Than One Way: Novel, Direct Inhibitors of Mycobacterium Tuberculosis Enoyl Acp Reductase To be Published
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4UVG
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![BU of 4uvg by Molmil](/molmil-images/mine/4uvg) | Discovery of pyrimidine isoxazoles InhA in complex with compound 15 | Descriptor: | 5-[(4,6-dimethylpyrimidin-2-yl)sulfanylmethyl]isoxazole-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], MAGNESIUM ION, ... | Authors: | Read, J.A, Gingell, H, Madhavapeddi, P, Ghorpade, S, Cowan, S. | Deposit date: | 2014-08-05 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Hitting the Target in More Than One Way: Novel, Direct Inhibitors of Mycobacterium Tuberculosis Enoyl Acp Reductase To be Published
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4UUV
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![BU of 4uuv by Molmil](/molmil-images/mine/4uuv) | Structure of the DNA binding ETS domain of human ETV4 in complex with DNA | Descriptor: | 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', ETS TRANSLOCATION VARIANT 4 | Authors: | Newman, J.A, Cooper, C.D.O, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | Deposit date: | 2014-07-31 | Release date: | 2014-08-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. J.Biol.Chem., 290, 2015
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4V3J
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![BU of 4v3j by Molmil](/molmil-images/mine/4v3j) | Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MONOTREME LACTATING PROTEIN | Authors: | Kumar, A, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R. | Deposit date: | 2014-10-20 | Release date: | 2016-01-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus. Acta Crystallogr F Struct Biol Commun, 74, 2018
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4V00
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![BU of 4v00 by Molmil](/molmil-images/mine/4v00) | Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MONOTREME LACTATING PROTEIN | Authors: | Enjapoori, A.K, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R. | Deposit date: | 2014-09-10 | Release date: | 2015-09-30 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus. Acta Crystallogr F Struct Biol Commun, 74, 2018
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4V6E
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![BU of 4v6e by Molmil](/molmil-images/mine/4v6e) | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Zhang, W, Dunkle, J.A, Cate, J.H.D. | Deposit date: | 2009-06-28 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3.712 Å) | Cite: | Structures of the ribosome in intermediate States of ratcheting. Science, 325, 2009
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4UTW
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![BU of 4utw by Molmil](/molmil-images/mine/4utw) | Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens | Descriptor: | CHLORIDE ION, N-acetyl-D-glucosamine-6-phosphate, PUTATIVE N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE | Authors: | Pelissier, M.C, Sebban-Kreuzer, C, Guerlesquin, F, Brannigan, J.A, Davies, G.J, Bourne, Y, Vincent, F. | Deposit date: | 2014-07-23 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Characterization of the Clostridium Perfringens N-Acetylmannosamine-6-Phosphate 2-Epimerase Essential for the Sialic Acid Salvage Pathway J.Biol.Chem., 289, 2014
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4V7T
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![BU of 4v7t by Molmil](/molmil-images/mine/4v7t) | Crystal structure of the E. coli ribosome bound to chloramphenicol. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | Deposit date: | 2010-08-14 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1942 Å) | Cite: | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
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4V97
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![BU of 4v97 by Molmil](/molmil-images/mine/4v97) | Crystal structure of the bacterial ribosome ram mutation G299A. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | Deposit date: | 2012-04-06 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.516 Å) | Cite: | Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc.Natl.Acad.Sci.USA, 110, 2013
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4WQC
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![BU of 4wqc by Molmil](/molmil-images/mine/4wqc) | Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208N mutant | Descriptor: | 1,2-ETHANEDIOL, HEME C, SULFATE ION, ... | Authors: | Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | Deposit date: | 2014-10-21 | Release date: | 2015-02-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
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4WQ8
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![BU of 4wq8 by Molmil](/molmil-images/mine/4wq8) | Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - tetrathionate soak | Descriptor: | HEME C, IODIDE ION, SULFATE ION, ... | Authors: | Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | Deposit date: | 2014-10-21 | Release date: | 2015-02-18 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.3989 Å) | Cite: | Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
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4WQ9
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![BU of 4wq9 by Molmil](/molmil-images/mine/4wq9) | Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - dithionite soak | Descriptor: | 1,2-ETHANEDIOL, HEME C, HYDROSULFURIC ACID, ... | Authors: | Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | Deposit date: | 2014-10-21 | Release date: | 2015-02-18 | Last modified: | 2021-09-08 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
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4WQA
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![BU of 4wqa by Molmil](/molmil-images/mine/4wqa) | Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - tetrathionate co-crystallization | Descriptor: | 1,2-ETHANEDIOL, HEME C, IODIDE ION, ... | Authors: | Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | Deposit date: | 2014-10-21 | Release date: | 2015-02-18 | Last modified: | 2015-04-15 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
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4WQE
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![BU of 4wqe by Molmil](/molmil-images/mine/4wqe) | Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208G mutant | Descriptor: | HEME C, IODIDE ION, SULFATE ION, ... | Authors: | Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | Deposit date: | 2014-10-21 | Release date: | 2015-02-18 | Last modified: | 2015-04-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
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4WQD
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![BU of 4wqd by Molmil](/molmil-images/mine/4wqd) | Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum - K208G mutant | Descriptor: | 1,2-ETHANEDIOL, GUANIDINE, HEME C, ... | Authors: | Brito, J.A, Denkmann, K, Pereira, I.A.C, Dahl, C, Archer, M. | Deposit date: | 2014-10-21 | Release date: | 2015-02-18 | Last modified: | 2015-04-15 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Thiosulfate Dehydrogenase (TsdA) from Allochromatium vinosum: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THIOSULFATE OXIDATION. J.Biol.Chem., 290, 2015
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4ZN9
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![BU of 4zn9 by Molmil](/molmil-images/mine/4zn9) | Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Oxabicyclic Heptene Sulfonate (OBHS) | Descriptor: | Estrogen receptor, Nuclear receptor-interacting peptide, cyclohexa-2,5-dien-1-yl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate | Authors: | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | Deposit date: | 2015-05-04 | Release date: | 2015-09-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.215 Å) | Cite: | Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands. Chemmedchem, 7, 2012
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8IJG
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![BU of 8ijg by Molmil](/molmil-images/mine/8ijg) | Crystal structure of alcohol dehydrogenase M5 from Burkholderia gladioli with NADP | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative short-chain dehydrogenases/reductase family protein | Authors: | Han, X, Mei, Z.L, Liu, W.D, Sun, Z.T, Ma, J.A. | Deposit date: | 2023-02-27 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of alcohol dehydrogenase from Burkholderia gladioli with NADP To Be Published
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8OET
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![BU of 8oet by Molmil](/molmil-images/mine/8oet) | SFX structure of the class II photolyase complexed with a thymine dimer | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, DNA (14-mer), Deoxyribodipyrimidine photo-lyase, ... | Authors: | Lane, T.J, Christou, N.-E, Melo, D.V.M, Apostolopoulou, V, Pateras, A, Mashhour, A.R, Galchenkova, M, Gunther, S, Reinke, P, Kremling, V, Oberthuer, D, Henkel, A, Sprenger, J, Scheer, T.E.S, Lange, E, Yefanov, O.N, Middendorf, P, Sellberg, J.A, Schubert, R, Fadini, A, Cirelli, C, Beale, E.V, Johnson, P, Dworkowski, F, Ozerov, D, Bertrand, Q, Wranik, M, Zitter, E.D, Turk, D, Bajt, S, Chapman, H, Bacellar, C. | Deposit date: | 2023-03-12 | Release date: | 2023-11-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Time-resolved crystallography captures light-driven DNA repair. Science, 382, 2023
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8OF5
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![BU of 8of5 by Molmil](/molmil-images/mine/8of5) | Crystal structure of Aurora A 122-403 C290A, N332A, Q335A, C393A bound to ADP | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Miles, J.A, Hammond, K.L.R, Bayliss, R. | Deposit date: | 2023-03-14 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of Aurora A 122-403 C290A, N332A, Q335A, C393A bound to ADP To Be Published
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8OJL
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![BU of 8ojl by Molmil](/molmil-images/mine/8ojl) | Human Mitochondrial Lon Y394E Mutant ADP Bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | Authors: | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | Deposit date: | 2023-03-24 | Release date: | 2024-04-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
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8OM7
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![BU of 8om7 by Molmil](/molmil-images/mine/8om7) | Human Mitochondrial Lon Y186E Mutant ADP Bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | Authors: | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | Deposit date: | 2023-03-31 | Release date: | 2024-04-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
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8OKA
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![BU of 8oka by Molmil](/molmil-images/mine/8oka) | Human Mitochondrial Lon Y394F Mutant ADP Bound | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | Authors: | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | Deposit date: | 2023-03-28 | Release date: | 2024-04-10 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions. Sci Rep, 14, 2024
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8PI2
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8IJ6
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![BU of 8ij6 by Molmil](/molmil-images/mine/8ij6) | Crystal structure of alcohol dehydrogenase from Burkholderia gladioli with NADP | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative short-chain dehydrogenases/reductase family protein | Authors: | Han, X, Mei, Z.L, Liu, W.D, Sun, Z.T, Ma, J.A. | Deposit date: | 2023-02-26 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal structure of alcohol dehydrogenase from Burkholderia gladioli with NADP To Be Published
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