4UTW

Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens

Summary for 4UTW

Entry DOI	10.2210/pdb4utw/pdb
Related	4UTT 4UTU
Descriptor	PUTATIVE N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE, CHLORIDE ION, N-acetyl-D-glucosamine-6-phosphate, ... (5 entities in total)
Functional Keywords	isomerase, sugar 2-epimerase, sialic acid, sugar phosphate, enzyme mechanism, carbohydrate, mutagenesis, 1h nmr spectroscopy
Biological source	CLOSTRIDIUM PERFRINGENS STR. 13 More
Total number of polymer chains	4
Total formula weight	101895.96
Authors	Pelissier, M.C.,Sebban-Kreuzer, C.,Guerlesquin, F.,Brannigan, J.A.,Davies, G.J.,Bourne, Y.,Vincent, F. (deposition date: 2014-07-23, release date: 2014-10-15, Last modification date: 2024-01-10)
Primary citation	Pelissier, M.C.,Sebban-Kreuzer, C.,Guerlesquin, F.,Brannigan, J.A.,Davies, G.J.,Bourne, Y.,Vincent, F. Structural and Functional Characterization of the Clostridium Perfringens N-Acetylmannosamine-6-Phosphate 2-Epimerase Essential for the Sialic Acid Salvage Pathway J.Biol.Chem., 289:35215-, 2014 Cited by PubMed: 25320079 DOI: 10.1074/JBC.M114.604272 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation