4UTW
Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| A | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| A | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| A | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| A | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| B | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| B | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| B | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| B | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| C | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| C | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| C | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| C | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006051 | biological_process | N-acetylmannosamine metabolic process |
| D | 0006053 | biological_process | N-acetylmannosamine catabolic process |
| D | 0016857 | molecular_function | racemase and epimerase activity, acting on carbohydrates and derivatives |
| D | 0019262 | biological_process | N-acetylneuraminate catabolic process |
| D | 0047465 | molecular_function | N-acylglucosamine-6-phosphate 2-epimerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1221 |
| Chain | Residue |
| A | ARG208 |
| A | PRO209 |
| A | GLN210 |
| A | HOH2069 |
| A | HOH2070 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE RFW A 1222 |
| Chain | Residue |
| A | TYR75 |
| A | THR147 |
| A | TYR151 |
| A | GLU180 |
| A | ARG182 |
| A | GLY203 |
| A | GLY204 |
| A | ARG208 |
| A | HOH2007 |
| A | HOH2051 |
| A | HOH2052 |
| A | HOH2133 |
| A | HOH2214 |
| A | HOH2219 |
| A | HOH2254 |
| A | HOH2255 |
| A | HOH2278 |
| A | HOH2282 |
| A | GLN14 |
| A | ARG43 |
| A | ILE64 |
| A | LYS66 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 1221 |
| Chain | Residue |
| B | ARG208 |
| B | PRO209 |
| B | GLN210 |
| B | HOH2060 |
| B | HOH2061 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE RFW B 1222 |
| Chain | Residue |
| B | GLN14 |
| B | ARG43 |
| B | ILE64 |
| B | LYS66 |
| B | TYR75 |
| B | THR147 |
| B | TYR151 |
| B | GLU180 |
| B | ARG182 |
| B | GLY203 |
| B | GLY204 |
| B | ARG208 |
| B | HOH2006 |
| B | HOH2048 |
| B | HOH2049 |
| B | HOH2196 |
| B | HOH2200 |
| B | HOH2230 |
| B | HOH2231 |
| B | HOH2247 |
| B | HOH2251 |
| B | HOH2265 |
| B | HOH2266 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 1221 |
| Chain | Residue |
| C | ARG208 |
| C | PRO209 |
| C | GLN210 |
| C | HOH2050 |
| C | HOH2051 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE RFW C 1222 |
| Chain | Residue |
| C | GLN14 |
| C | ARG43 |
| C | ILE64 |
| C | LYS66 |
| C | TYR75 |
| C | ILE76 |
| C | TYR151 |
| C | GLU180 |
| C | GLY181 |
| C | ARG182 |
| C | GLY203 |
| C | GLY204 |
| C | ARG208 |
| C | HOH2036 |
| C | HOH2039 |
| C | HOH2169 |
| C | HOH2173 |
| C | HOH2199 |
| C | HOH2200 |
| C | HOH2213 |
| C | HOH2232 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1221 |
| Chain | Residue |
| D | ARG208 |
| D | PRO209 |
| D | GLN210 |
| D | HOH2044 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE RFW D 1222 |
| Chain | Residue |
| D | HOH2147 |
| D | HOH2153 |
| D | HOH2171 |
| D | HOH2172 |
| D | HOH2188 |
| D | HOH2193 |
| D | GLN14 |
| D | ARG43 |
| D | ILE64 |
| D | LYS66 |
| D | TYR75 |
| D | THR147 |
| D | TYR151 |
| D | GLU180 |
| D | ARG182 |
| D | GLY203 |
| D | GLY204 |
| D | ARG208 |
| D | HOH2030 |
| D | HOH2033 |
