1QMB
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![BU of 1qmb by Molmil](/molmil-images/mine/1qmb) | Cleaved alpha-1-antitrypsin polymer | Descriptor: | ALPHA-1-ANTITRYPSIN | Authors: | Huntington, J.A, Pannu, N.S, Hazes, B, Read, R.J, Lomas, D.A, Carrell, R.W. | Deposit date: | 1999-09-24 | Release date: | 2000-02-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A 2.6A Structure of a Serpin Polymer and Implications for Conformational Disease J.Mol.Biol., 293, 1999
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1E9H
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![BU of 1e9h by Molmil](/molmil-images/mine/1e9h) | Thr 160 phosphorylated CDK2 - Human cyclin A3 complex with the inhibitor indirubin-5-sulphonate bound | Descriptor: | 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID, CELL DIVISION PROTEIN KINASE 2, CYCLIN A3 | Authors: | Davies, T.G, Tunnah, P, Noble, M.E.M, Endicott, J.A. | Deposit date: | 2000-10-16 | Release date: | 2001-10-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Inhibitor Binding to Active and Inactive Cdk2: The Crystal Structure of Cdk2-Cyclin A/Indirubin-5-Sulphonate Structure, 9, 2001
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1R1L
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![BU of 1r1l by Molmil](/molmil-images/mine/1r1l) | Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin P14-P9 peptide, Antithrombin-III, ... | Authors: | Zhou, A, Huntington, J.A, Lomas, D.A, Stein, P.E, Carrell, R.W. | Deposit date: | 2003-09-24 | Release date: | 2004-10-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Serpins and the design of peptides to block intermolecular beta-linkages To be Published
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1EF8
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![BU of 1ef8 by Molmil](/molmil-images/mine/1ef8) | CRYSTAL STRUCTURE OF METHYLMALONYL COA DECARBOXYLASE | Descriptor: | METHYLMALONYL COA DECARBOXYLASE, NICKEL (II) ION | Authors: | Benning, M.M, Haller, T, Gerlt, J.A, Holden, H.M. | Deposit date: | 2000-02-07 | Release date: | 2000-05-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | New reactions in the crotonase superfamily: structure of methylmalonyl CoA decarboxylase from Escherichia coli. Biochemistry, 39, 2000
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1RJ4
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![BU of 1rj4 by Molmil](/molmil-images/mine/1rj4) | Structure of a Cell Wall Invertase Inhibitor from Tobacco in Complex with Cd2+ | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, invertase inhibitor | Authors: | Hothorn, M, D'Angelo, I, Marquez, J.A, Greiner, S, Scheffzek, K. | Deposit date: | 2003-11-18 | Release date: | 2004-02-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The invertase inhibitor Nt-CIF from tobacco: a highly thermostable four-helix bundle with an unusual N-terminal extension J.Mol.Biol., 335, 2004
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1RQ7
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![BU of 1rq7 by Molmil](/molmil-images/mine/1rq7) | MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH GDP | Descriptor: | Cell division protein ftsZ, GUANOSINE-5'-DIPHOSPHATE | Authors: | Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W. | Deposit date: | 2003-12-04 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches. J.Mol.Biol., 342, 2004
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1E63
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![BU of 1e63 by Molmil](/molmil-images/mine/1e63) | Ferredoxin:NADP+ Reductase Mutant with LYS 75 Replaced by SER (K75S) | Descriptor: | FERREDOXIN-NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | Authors: | Hermoso, J.A, Mayoral, T, Medina, M, Gomez-Moreno, C. | Deposit date: | 2000-08-07 | Release date: | 2001-05-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Analysis of Interactions for Complex Formation between Ferredoxin-Nadp+ Reductase and its Protein Partners. Proteins, 59, 2005
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1EU4
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![BU of 1eu4 by Molmil](/molmil-images/mine/1eu4) | CRYSTAL STRUCTURE OF THE SUPERANTIGEN SPE-H (ZINC BOUND) FROM STREPTOCOCCUS PYOGENES | Descriptor: | SUPERANTIGEN SPE-H, ZINC ION | Authors: | Arcus, V.L, Proft, T, Sigrell, J.A, Baker, H.M, Fraser, J.D, Baker, E.N. | Deposit date: | 2000-04-13 | Release date: | 2000-04-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes. J.Mol.Biol., 299, 2000
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1RD3
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![BU of 1rd3 by Molmil](/molmil-images/mine/1rd3) | 2.5A Structure of Anticoagulant Thrombin Variant E217K | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, PHOSPHATE ION, ... | Authors: | Carter, W.J, Myles, T, Leung, L.L, Huntington, J.A. | Deposit date: | 2003-11-05 | Release date: | 2004-05-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery J.Biol.Chem., 279, 2004
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1EPS
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![BU of 1eps by Molmil](/molmil-images/mine/1eps) | STRUCTURE AND TOPOLOGICAL SYMMETRY OF THE GLYPHOSPHATE 5-ENOL-PYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE: A DISTINCTIVE PROTEIN FOLD | Descriptor: | 5-ENOL-PYRUVYL-3-PHOSPHATE SYNTHASE | Authors: | Stallings, W.C, Abdel-Meguid, S.S, Lim, L.W, Shieh, H.-S, Dayringer, H.E, Leimgruber, N.K, Stegeman, R.A, Anderson, K.S, Sikorski, J.A, Padgette, S.R, Kishore, G.M. | Deposit date: | 1991-04-05 | Release date: | 1993-07-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold. Proc.Natl.Acad.Sci.USA, 88, 1991
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1RMX
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![BU of 1rmx by Molmil](/molmil-images/mine/1rmx) | A SHORT LEXITROPSIN THAT RECOGNIZES THE DNA MINOR GROOVE AT 5'-ACTAGT-3': UNDERSTANDING THE ROLE OF ISOPROPYL-THIAZOLE | Descriptor: | 5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3', N-[3-(DIMETHYLAMINO)PROPYL]-2-({[4-({[4-(FORMYLAMINO)-1-METHYL-1H-PYRROL-2-YL]CARBONYL}AMINO)-1-METHYL-1H-PYRROL-2-YL]CARBONYL}AMINO)-5-ISOPROPYL-1,3-THIAZOLE-4-CARBOXAMIDE | Authors: | Anthony, N.G, Johnston, B.F, Khalaf, A.I, Mackay, S.P, Parkinson, J.A, Suckling, C.J, Waigh, R.D. | Deposit date: | 2003-11-28 | Release date: | 2004-08-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Short Lexitropsin that Recognizes the DNA Minor Groove at 5'-ACTAGT-3': Understanding the Role of Isopropyl-thiazole. J.Am.Chem.Soc., 126, 2004
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1E80
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![BU of 1e80 by Molmil](/molmil-images/mine/1e80) | Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD56133 | Descriptor: | 4-amino-N-{(1R,8R,9R,13R)-16-(4-amino-2-methylpyrimidin-5-yl)-1-benzyl-8-(cyclohexylmethyl)-9-hydroxy-13-[(1S)-1-methylpropyl]-2,6,11,14-tetraoxo-3,7,12,15-tetraazahexadec-1-yl}piperidine-1-carboxamide, ENDOTHIAPEPSIN | Authors: | Read, J.A, Cooper, J.B, Toldo, L, Rippmann, F, Raddatz, P. | Deposit date: | 2000-09-15 | Release date: | 2000-09-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Ph D Thesis, 1999
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1EH7
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![BU of 1eh7 by Molmil](/molmil-images/mine/1eh7) | |
1EKD
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![BU of 1ekd by Molmil](/molmil-images/mine/1ekd) | NMR AND MOLECULAR MODELING REVEAL THAT DIFFERENT HYDROGEN BONDING PATTERNS ARE POSSIBLE FOR GU PAIRS: ONE HYDROGEN BOND FOR EACH GU PAIR IN R(GGCGUGCC)2 AND TWO FOR EACH GU PAIR IN R(GAGUGCUC)2 | Descriptor: | RNA (5'-R(*GP*GP*CP*GP*UP*GP*CP*C)-3') | Authors: | Chen, X, McDowell, J.A, Kierzek, R, Krugh, T.R, Turner, D.H. | Deposit date: | 2000-03-07 | Release date: | 2000-11-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance spectroscopy and molecular modeling reveal that different hydrogen bonding patterns are possible for G.U pairs: one hydrogen bond for each G.U pair in r(GGCGUGCC)(2) and two for each G.U pair in r(GAGUGCUC)(2). Biochemistry, 39, 2000
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1EKX
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![BU of 1ekx by Molmil](/molmil-images/mine/1ekx) | THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE) | Descriptor: | ASPARTATE TRANSCARBAMOYLASE, CALCIUM ION, N-(PHOSPHONACETYL)-L-ASPARTIC ACID | Authors: | Endrizzi, J.A, Beernink, P.T, Alber, T, Schachman, H.K. | Deposit date: | 2000-03-09 | Release date: | 2000-05-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation induced cell migration. Proc.Natl.Acad.Sci.USA, 97, 2000
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1E5N
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![BU of 1e5n by Molmil](/molmil-images/mine/1e5n) | E246C mutant of P fluorescens subsp. cellulosa xylanase A in complex with xylopentaose | Descriptor: | CALCIUM ION, ENDO-1,4-BETA-XYLANASE A, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | Lo Leggio, L, Jenkins, J.A, Harris, G.W, Pickersgill, R.W. | Deposit date: | 2000-07-27 | Release date: | 2000-12-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | X-ray crystallographic study of xylopentaose binding to Pseudomonas fluorescens xylanase A. Proteins, 41, 2000
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1ET6
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![BU of 1et6 by Molmil](/molmil-images/mine/1et6) | CRYSTAL STRUCTURE OF THE SUPERANTIGEN SMEZ-2 FROM STREPTOCOCCUS PYOGENES | Descriptor: | SUPERANTIGEN SMEZ-2 | Authors: | Arcus, V.L, Proft, T, Sigrell, J.A, Baker, H.M, Fraser, J.D, Baker, E.N. | Deposit date: | 2000-04-12 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes. J.Mol.Biol., 299, 2000
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1EU3
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![BU of 1eu3 by Molmil](/molmil-images/mine/1eu3) | CRYSTAL STRUCTURE OF THE SUPERANTIGEN SMEZ-2 (ZINC BOUND) FROM STREPTOCOCCUS PYOGENES | Descriptor: | PHOSPHATE ION, POTASSIUM ION, SUPERANTIGEN SMEZ-2, ... | Authors: | Arcus, V.L, Proft, T, Sigrell, J.A, Baker, H.M, Fraser, J.D, Baker, E.N. | Deposit date: | 2000-04-13 | Release date: | 2000-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes. J.Mol.Biol., 299, 2000
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1R9G
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![BU of 1r9g by Molmil](/molmil-images/mine/1r9g) | Three-dimensional Structure of YaaE from Bacillus subtilis | Descriptor: | Hypothetical protein yaaE | Authors: | Bauer, J.A, Bennett, E.M, Begley, T.P, Ealick, S.E. | Deposit date: | 2003-10-29 | Release date: | 2004-01-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Three-dimensional Structure of YaaE from Bacillus subtilis, a Glutaminase Implicated in Pyridoxal-5'-phosphate Biosynthesis. J.Biol.Chem., 279, 2004
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1R6W
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![BU of 1r6w by Molmil](/molmil-images/mine/1r6w) | Crystal structure of the K133R mutant of o-Succinylbenzoate synthase (OSBS) from Escherichia coli. Complex with SHCHC | Descriptor: | 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, MAGNESIUM ION, o-Succinylbenzoate Synthase | Authors: | Klenchin, V.A, Taylor Ringia, E.A, Gerlt, J.A, Rayment, I. | Deposit date: | 2003-10-17 | Release date: | 2003-11-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Evolution of Enzymatic Activity in the Enolase Superfamily: Structural and Mutagenic Studies of the Mechanism of the Reaction Catalyzed by o-Succinylbenzoate Synthase from Escherichia coli Biochemistry, 42, 2003
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1RQ2
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![BU of 1rq2 by Molmil](/molmil-images/mine/1rq2) | MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH CITRATE | Descriptor: | CITRIC ACID, Cell division protein ftsZ | Authors: | Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W. | Deposit date: | 2003-12-04 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches. J.Mol.Biol., 342, 2004
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1RTX
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![BU of 1rtx by Molmil](/molmil-images/mine/1rtx) | Crystal Structure of Synechocystis Hemoglobin with a Covalent Heme Linkage | Descriptor: | CADMIUM ION, Cyanoglobin, POTASSIUM ION, ... | Authors: | Hoy, J.A, Kundu, S, Trent, J.T, Ramaswamy, S, Hargrove, M.S. | Deposit date: | 2003-12-10 | Release date: | 2004-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of synechocystis hemoglobin with a covalent heme linkage. J.Biol.Chem., 279, 2004
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1RJ1
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![BU of 1rj1 by Molmil](/molmil-images/mine/1rj1) | Crystal Structure of a Cell Wall Invertase Inhibitor from Tobacco | Descriptor: | invertase inhibitor | Authors: | Hothorn, M, D'Angelo, I, Marquez, J.A, Greiner, S, Scheffzek, K. | Deposit date: | 2003-11-18 | Release date: | 2004-02-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | The invertase inhibitor Nt-CIF from tobacco: a highly thermostable four-helix bundle with an unusual N-terminal extension J.Mol.Biol., 335, 2004
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1RLU
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![BU of 1rlu by Molmil](/molmil-images/mine/1rlu) | Mycobacterium tuberculosis FtsZ in complex with GTP-gamma-S | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein ftsZ, GLYCEROL | Authors: | Leung, A.K.W, White, E.L, Ross, L.J, Reynolds, R.C, DeVito, J.A, Borhani, D.W. | Deposit date: | 2003-11-26 | Release date: | 2004-08-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches. J.Mol.Biol., 342, 2004
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4K1X
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![BU of 4k1x by Molmil](/molmil-images/mine/4k1x) | Ferredoxin-NADP(H) Reductase mutant with Ala 266 replaced by Tyr (A266Y) and residues 267-272 deleted. | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH:ferredoxin reductase, SULFATE ION | Authors: | Bortolotti, A, Sanchez-Azqueta, A, Maya, C.M, Velazquez-Campoy, A, Hermoso, J.A, Cortez, N. | Deposit date: | 2013-04-06 | Release date: | 2013-11-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The C-terminal extension of bacterial flavodoxin-reductases: Involvement in the hydride transfer mechanism from the coenzyme. Biochim.Biophys.Acta, 1837, 2013
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