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PDB: 42507 results

1RX9
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BU of 1rx9 by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor: BETA-MERCAPTOETHANOL, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ...
Authors:Sawaya, M.R, Kraut, J.
Deposit date:1996-10-25
Release date:1997-04-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
7OIA
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BU of 7oia by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
3ZXY
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BU of 3zxy by Molmil
Structure of S218A mutant of the protease domain of PatA
Descriptor: SUBTILISIN-LIKE PROTEIN
Authors:Koehnke, J, Zollman, D, Vendome, J, Raab, A, Houssen, W.E, Smith, M.C, Jaspars, M, Naismith, J.H.
Deposit date:2011-08-16
Release date:2012-08-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:The Discovery of New Cyanobactins from Cyanothece Pcc 7425 Defines a New Signature for Processing of Patellamides.
Chembiochem, 13, 2012
7OI7
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Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
2P4U
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BU of 2p4u by Molmil
Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus
Descriptor: Acid phosphatase 1, PHOSPHATE ION
Authors:Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-03-13
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
7OIE
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BU of 7oie by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
7OIC
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BU of 7oic by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
1RY6
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BU of 1ry6 by Molmil
Crystal Structure of Internal Kinesin Motor Domain
Descriptor: INTERNAL KINESIN, SULFATE ION
Authors:Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R.
Deposit date:2003-12-19
Release date:2004-04-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of a kinesin microtubule depolymerization machine.
Embo J., 23, 2004
3L3G
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BU of 3l3g by Molmil
Crystal structure of HLA-B*4402 in complex with the R5A mutant of a self-peptide derived from DPA*0201
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Theodossis, A, Ely, L.K, Rossjohn, J.
Deposit date:2009-12-16
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
7OJ0
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BU of 7oj0 by Molmil
Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R.
Deposit date:2021-05-13
Release date:2021-09-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
7OIB
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BU of 7oib by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Cheng, J, Berninghausen, O, Beckmann, R.
Deposit date:2021-05-11
Release date:2021-09-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
2P6G
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BU of 2p6g by Molmil
Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors
Descriptor: 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
Authors:Wu, J, Ding, J.
Deposit date:2007-03-18
Release date:2007-06-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
7OIZ
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BU of 7oiz by Molmil
Cryo-EM structure of 70S ribosome stalled with TnaC peptide
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R.
Deposit date:2021-05-13
Release date:2021-09-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
2P8T
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BU of 2p8t by Molmil
Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
Descriptor: Hypothetical protein PH0730
Authors:Chen, L, Zhao, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhu, J, Swindell, J.T, Fu, Z.-Q, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-23
Release date:2007-04-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
To be Published
4QXI
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BU of 4qxi by Molmil
Crystal structure of human AR complexed with NADP+ and AK198
Descriptor: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2-[(4-amino-2-fluorobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid
Authors:Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Hobza, P, Podjarny, A.D.
Deposit date:2014-07-21
Release date:2015-07-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (0.867 Å)
Cite:The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition.
Acs Chem.Biol., 10, 2015
3ZJ8
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BU of 3zj8 by Molmil
Crystal structure of strictosidine glucosidase in complex with inhibitor-2
Descriptor: (1R,2S,3S,4R,5R)-4-[(4-bromophenyl)methylamino]-5-(hydroxymethyl)cyclopentane-1,2,3-triol, STRICTOSIDINE-O-BETA-D-GLUCOSIDASE
Authors:Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J.
Deposit date:2013-01-17
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
4CYI
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BU of 4cyi by Molmil
Chaetomium thermophilum Pan3
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
7OA6
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BU of 7oa6 by Molmil
Pseudo-atomic model for Hsp26 residues 63 to 214. Please be advised that the target map is not of sufficient resolution to unambiguously position backbone or side chain atoms. This model represents a likely fit.
Descriptor: Heat shock protein 26
Authors:Muehlhofer, M, Peters, C, Kriehuber, T, Kreuzeder, M, Kazman, P, Rodina, N, Reif, B, Haslbeck, M, Weinkauf, S, Buchner, J.
Deposit date:2021-04-19
Release date:2021-11-24
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble.
Nat Commun, 12, 2021
4D3Y
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BU of 4d3y by Molmil
The structure of inactive prolegumain from chinese hamster.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LEGUMAIN
Authors:Li, W, Heinz, D.W, Krausze, J.
Deposit date:2014-10-24
Release date:2016-01-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Detailed Look Into Chinese Hamster Legumain Active Site Structure and Exploration of its Function
To be Published
4D5V
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BU of 4d5v by Molmil
Hypocrea jecorina cellobiohydrolase Cel7A E217Q soaked with xylotetraose.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULOSE 1,4-BETA-CELLOBIOSIDASE, COBALT (II) ION, ...
Authors:Momeni, M.H, Stahlberg, J, Hansson, H.
Deposit date:2014-11-07
Release date:2015-03-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural Insights Into the Inhibition of Cellobiohydrolase Cel7A by Xylooligosaccharides.
FEBS J., 282, 2015
4D5P
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BU of 4d5p by Molmil
Hypocrea jecorina cellobiohydrolase Cel7A E217Q soaked with xylopentaose.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULOSE 1,4-BETA-CELLOBIOSIDASE, COBALT (II) ION, ...
Authors:Momeni, M.H, Ubhayasekera, W, Stahlberg, J, Hansson, H.
Deposit date:2014-11-07
Release date:2015-03-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Insights Into the Inhibition of Cellobiohydrolase Cel7A by Xylooligosaccharides.
FEBS J., 282, 2015
2P7F
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BU of 2p7f by Molmil
The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme
Descriptor: COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ...
Authors:Torelli, A.T, Krucinska, J, Wedekind, J.E.
Deposit date:2007-03-20
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
1GKA
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BU of 1gka by Molmil
The molecular basis of the coloration mechanism in lobster shell. beta-crustacyanin at 3.2 A resolution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ASTAXANTHIN, ...
Authors:Cianci, M, Rizkallah, P.J, Olczak, A, Raftery, J, Chayen, N.E, Zagalsky, P.F, Helliwell, J.R.
Deposit date:2001-08-10
Release date:2002-08-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:The Molecular Basis of the Coloration Mechanism in Lobster Shell: Beta -Crustacyanin at 3.2-A Resolution
Proc.Natl.Acad.Sci.USA, 99, 2002
6AUC
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BU of 6auc by Molmil
Artificial metalloproteins containing a Co4O4 active site - 2xm-Sav
Descriptor: N-biotin-C-Co4(mu3-O)4(Py)4(H2O)4-beta-alanine, Streptavidin
Authors:Olshansky, L, Vallapurackal, J, Huerta-Lavorie, R, Tilley, T.D, Borovik, A.S.
Deposit date:2017-08-31
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Artificial Metalloproteins Containing Co
J. Am. Chem. Soc., 140, 2018
3HMX
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BU of 3hmx by Molmil
Crystal structure of ustekinumab FAB/IL-12 complex
Descriptor: Interleukin-12 subunit alpha, Interleukin-12 subunit beta, USTEKINUMAB FAB HEAVY CHAIN, ...
Authors:Luo, J.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab.
J.Mol.Biol., 402, 2010

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