1JCC
| Crystal Structure of a Novel Alanine-Zipper Trimer at 1.7 A Resolution, V13A,L16A,V20A,L23A,V27A,M30A,V34A mutations | Descriptor: | MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION | Authors: | Liu, J, Dai, J, Lu, M. | Deposit date: | 2001-06-08 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Zinc-Mediated Helix Capping in A Triple-Helical Protein Biochemistry, 42, 2003
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1WQM
| CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, LYSOZYME, SODIUM ION | Authors: | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | Deposit date: | 1998-02-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
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4I05
| Structure of intermediate processing form of cathepsin B1 from Schistosoma mansoni | Descriptor: | Cathepsin B-like peptidase (C01 family), SODIUM ION | Authors: | Rezacova, P, Jilkova, A, Brynda, J, Horn, M, Mares, M. | Deposit date: | 2012-11-16 | Release date: | 2014-02-05 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch Structure, 22, 2014
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1WQO
| CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, LYSOZYME, SODIUM ION | Authors: | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | Deposit date: | 1998-02-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
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8BZN
| SARS-CoV-2 non-structural protein 10 (nsp10) variant T102I | Descriptor: | CHLORIDE ION, DIMETHYL SULFOXIDE, Replicase polyprotein 1ab, ... | Authors: | Wang, H, Rizvi, S.R.A, Dong, D, Lou, J, Wang, Q, Sopipong, W, Najar, F, Agarwal, P.K, Kozielski, F, Haider, S. | Deposit date: | 2022-12-15 | Release date: | 2023-12-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16. Elife, 12, 2023
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1WQP
| CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, LYSOZYME, SODIUM ION | Authors: | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | Deposit date: | 1998-02-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
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1WQN
| CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, LYSOZYME, SODIUM ION | Authors: | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | Deposit date: | 1998-02-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
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6INS
| X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE | Descriptor: | INSULIN, ZINC ION | Authors: | Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. | Deposit date: | 1992-11-25 | Release date: | 1994-01-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J.Mol.Biol., 220, 1991
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1WQQ
| CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, LYSOZYME, SODIUM ION | Authors: | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | Deposit date: | 1998-02-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
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1WQR
| CONTRIBUTION OF HYDROGEN BONDS TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | Descriptor: | CHLORIDE ION, LYSOZYME, SODIUM ION | Authors: | Yamagata, Y, Kubota, M, Sumikawa, Y, Funahashi, J, Fujii, S, Yutani, K. | Deposit date: | 1998-02-09 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants. Biochemistry, 37, 1998
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8BYX
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8BZL
| Human 20S Proteasome in complex with peptide activator peptide BLM42 | Descriptor: | ARG-SER-TYR-TYR-SER, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Henneberg, F, Chari, A, Jankowska, E, Witkowska, J. | Deposit date: | 2022-12-15 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Peptidic, Blm10-based activators of human 20S proteasome in vitro and in cellulo enhance degradation of proteins connected with neurodegeneration. To Be Published
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8BZM
| FOXK1-ELF1-heterodimer bound to DNA | Descriptor: | DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ... | Authors: | Morgunova, E, Popov, A, Yin, Y, Taipale, J. | Deposit date: | 2022-12-15 | Release date: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | FOXK1-ELF1_heterodimer bound to DNA To Be Published
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1XI1
| Phi29 DNA polymerase ssDNA complex, monoclinic crystal form | Descriptor: | 5'-D(P*TP*TP*TP*TP*T)-3', DNA polymerase, MAGNESIUM ION | Authors: | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | Deposit date: | 2004-09-21 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Correction of X-ray intensities from single crystals containing lattice-translocation defects Acta Crystallogr.,Sect.D, 61, 2005
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8C15
| Aurora A kinase in complex with TPX2-inhibitor 3 | Descriptor: | (1~{R},2~{R})-cyclohexane-1,2-dicarboxylic acid, 4-(4-chlorophenyl)-1~{H}-indole-6-carboxylic acid, ACETATE ION, ... | Authors: | Fischer, G, Rocaboy, M, Blaszczyk, B, Moschetti, T, Wang, X, Scott, D.E, Coyne, A.G, Dagostin, C, Rooney, T, Bayly, A, Feng, J, Asteian, A, Alcaide-Lopez, A, Stockwell, S, Skidmore, J, Venkitaraman, A.R, Abell, C, Blundell, T.L, Hyvonen, M. | Deposit date: | 2022-12-20 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents To be published
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1C1E
| CRYSTAL STRUCTURE OF A DIELS-ALDERASE CATALYTIC ANTIBODY 1E9 IN COMPLEX WITH ITS HAPTEN | Descriptor: | 1,7,8,9,10,10-HEXACHLORO-4-METHYL-4-AZA-TRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE, CATALYTIC ANTIBODY 1E9 (HEAVY CHAIN), CATALYTIC ANTIBODY 1E9 (LIGHT CHAIN), ... | Authors: | Xu, J, Wilson, I.A. | Deposit date: | 1999-07-22 | Release date: | 2000-03-01 | Last modified: | 2013-01-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evolution of shape complementarity and catalytic efficiency from a primordial antibody template. Science, 286, 1999
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4I6S
| Structure of RSL mutant W76A in complex with L-fucose | Descriptor: | 1,2-ETHANEDIOL, Putative fucose-binding lectin protein, TETRAETHYLENE GLYCOL, ... | Authors: | Audfray, A, Arnaud, J, Varrot, A, Imberty, A. | Deposit date: | 2012-11-30 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Reduction of lectin valency drastically changes glycolipid dynamics in membranes but not surface avidity Acs Chem.Biol., 8, 2013
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8CD1
| 70S-PHIKZ014 | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Gerovac, M, Vogel, J. | Deposit date: | 2023-01-29 | Release date: | 2024-01-24 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Phage proteins target and co-opt host ribosomes immediately upon infection. Nat Microbiol, 9, 2024
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8C1J
| Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_18-30 | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, Protein arginine N-methyltransferase 2, RNA-binding protein Rsf1-like | Authors: | Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. | Deposit date: | 2022-12-20 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_18-30 To Be Published
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8BY6
| Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | Authors: | Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. | Deposit date: | 2022-12-12 | Release date: | 2024-01-24 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
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4MIV
| Crystal Structure of Sulfamidase, Crystal Form L | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Sidhu, N.S, Uson, I, Schreiber, K, Proepper, K, Becker, S, Sheldrick, G.M, Gaertner, J, Kraetzner, R, Steinfeld, R. | Deposit date: | 2013-09-02 | Release date: | 2014-05-14 | Last modified: | 2021-06-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA. Acta Crystallogr.,Sect.D, 70, 2014
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2NPM
| crystal structure of Cryptosporidium parvum 14-3-3 protein in complex with peptide | Descriptor: | 14-3-3 domain containing protein, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS | Authors: | Dong, A, Lew, J, Wasney, G, Ren, H, Lin, L, Hassanali, A, Qiu, W, Zhao, Y, Doyle, D, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-10-27 | Release date: | 2006-11-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Characterization of 14-3-3 proteins from Cryptosporidium parvum. Plos One, 6, 2011
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1X9Y
| The prostaphopain B structure | Descriptor: | cysteine proteinase | Authors: | Filipek, R, Szczepanowski, R, Sabat, A, Potempa, J, Bochtler, M. | Deposit date: | 2004-08-24 | Release date: | 2004-11-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition. Biochemistry, 43, 2004
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4HOZ
| The crystal structure of isomaltulose synthase mutant D241A from Erwinia rhapontici NX5 in complex with D-glucose | Descriptor: | CALCIUM ION, GLYCEROL, Sucrose isomerase, ... | Authors: | Xu, Z, Li, S, Xu, H, Zhou, J. | Deposit date: | 2012-10-23 | Release date: | 2013-10-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structural Basis of Erwinia rhapontici Isomaltulose Synthase Plos One, 8, 2013
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1JQJ
| Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of the beta-delta complex | Descriptor: | DNA polymerase III, beta chain, delta subunit | Authors: | Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J. | Deposit date: | 2001-08-07 | Release date: | 2001-11-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 106, 2001
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