8RH1
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![BU of 8rh1 by Molmil](/molmil-images/mine/8rh1) | Trimeric HSV-2F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. | Descriptor: | Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain | Authors: | Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. | Deposit date: | 2023-12-14 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31, 2024
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2G73
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![BU of 2g73 by Molmil](/molmil-images/mine/2g73) | Y104F mutant type 1 IPP isomerase complex with EIPP | Descriptor: | 4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ... | Authors: | de Ruyck, J, Wouters, J. | Deposit date: | 2006-02-27 | Release date: | 2006-04-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography. J.Biol.Chem., 281, 2006
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8RNU
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2GEJ
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![BU of 2gej by Molmil](/molmil-images/mine/2gej) | Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man | Descriptor: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, PHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE (PimA) | Authors: | Guerin, M.E, Buschiazzo, A, Kordulakova, J, Jackson, M, Alzari, P.M. | Deposit date: | 2006-03-20 | Release date: | 2007-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria. J.Biol.Chem., 282, 2007
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1GJU
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![BU of 1gju by Molmil](/molmil-images/mine/1gju) | Maltosyltransferase from Thermotoga maritima | Descriptor: | MALTODEXTRIN GLYCOSYLTRANSFERASE, PHOSPHATE ION | Authors: | Roujeinikova, A, Raasch, C, Burke, J, Baker, P.J, Liebl, W, Rice, D.W. | Deposit date: | 2001-08-02 | Release date: | 2001-09-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of Thermotoga Maritima Maltosyltransferase and its Implications for the Molecular Basis of the Novel Transfer Specificity J.Mol.Biol., 312, 2001
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1GMP
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![BU of 1gmp by Molmil](/molmil-images/mine/1gmp) | COMPLEX OF RIBONUCLEASE FROM STREPTOMYCES AUREOFACIENS WITH 2'-GMP AT 1.7 ANGSTROMS RESOLUTION | Descriptor: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE SA, SULFATE ION | Authors: | Sevcik, J, Hill, C, Dauter, Z, Wilson, K. | Deposit date: | 1992-10-01 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Complex of ribonuclease from Streptomyces aureofaciens with 2'-GMP at 1.7 A resolution. Acta Crystallogr.,Sect.D, 49, 1993
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7BV3
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![BU of 7bv3 by Molmil](/molmil-images/mine/7bv3) | Crystal structure of a ugt transferase from Siraitia grosvenorii in complex with UDP | Descriptor: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE | Authors: | Li, J, Shan, N, Yang, J.G, Liu, W.D, Sun, Y.X. | Deposit date: | 2020-04-09 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Near-perfect control of the regioselective glucosylation enabled by rational design of glycosyltransferases Green Synth Catal, 2021
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7BC3
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![BU of 7bc3 by Molmil](/molmil-images/mine/7bc3) | Native virion of Kashmir bee virus at acidic pH | Descriptor: | Structural polyprotein | Authors: | Mukhamedova, L, Plevka, P, Fuzik, T, Hrebik, D, Novacek, J. | Deposit date: | 2020-12-18 | Release date: | 2021-03-03 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Virion structure and in vitro genome release mechanism of dicistrovirus Kashmir bee virus. J.Virol., 95, 2021
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2GC8
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![BU of 2gc8 by Molmil](/molmil-images/mine/2gc8) | Structure of a Proline Sulfonamide Inhibitor Bound to HCV NS5b Polymerase | Descriptor: | 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE, RNA-directed RNA polymerase | Authors: | Gopalsamy, A, Chopra, R, Lim, K, Ciszewski, G, Shi, M, Curran, K.J, Sukits, S.F, Svenson, K, Bard, J, Ellingboe, J.W, Agarwal, A, Krishnamurthy, G, Howe, A.Y, Orlowski, M, Feld, B, O'connell, J, Mansour, T.S. | Deposit date: | 2006-03-13 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site. J.Med.Chem., 49, 2006
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3L42
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![BU of 3l42 by Molmil](/molmil-images/mine/3l42) | PWWP domain of human bromodomain and PHD finger containing protein 1 | Descriptor: | Peregrin, UNKNOWN ATOM OR ION | Authors: | Tempel, W, Zeng, H, Ni, S, Amaya, M.F, Dong, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-12-18 | Release date: | 2010-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural and Histone Binding Ability Characterizations of Human PWWP Domains. Plos One, 6, 2011
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6W8S
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![BU of 6w8s by Molmil](/molmil-images/mine/6w8s) | Crystal structure of metacaspase 4 from Arabidopsis | Descriptor: | Metacaspase-4, SULFATE ION | Authors: | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | Deposit date: | 2020-03-21 | Release date: | 2020-05-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.484 Å) | Cite: | Structural basis for Ca2+-dependent activation of a plant metacaspase. Nat Commun, 11, 2020
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6VWA
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1GMR
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![BU of 1gmr by Molmil](/molmil-images/mine/1gmr) | COMPLEX OF RIBONUCLEASE FROM STREPTOMYCES AUREOFACIENS WITH 2'-GMP AT 1.7 ANGSTROMS RESOLUTION | Descriptor: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE SA, SULFATE ION | Authors: | Sevcik, J, Hill, C, Dauter, Z, Wilson, K. | Deposit date: | 1992-10-01 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Complex of ribonuclease from Streptomyces aureofaciens with 2'-GMP at 1.7 A resolution. Acta Crystallogr.,Sect.D, 49, 1993
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6WBH
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![BU of 6wbh by Molmil](/molmil-images/mine/6wbh) | Crystal structure of mRECK(CC4) in fusion with engineered MBP at medium resolution | Descriptor: | CHLORIDE ION, Maltodextrin-binding protein,Reversion-inducing cysteine-rich protein with Kazal motifs fusion, ZINC ION, ... | Authors: | Chang, T.H, Hsieh, F.L, Gabelli, S.B, Nathans, J. | Deposit date: | 2020-03-26 | Release date: | 2020-06-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.455 Å) | Cite: | Structure of the RECK CC domain, an evolutionary anomaly. Proc.Natl.Acad.Sci.USA, 117, 2020
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1GN7
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7TXH
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![BU of 7txh by Molmil](/molmil-images/mine/7txh) | Human MRas Q71R in complex with human Shoc2 LRR domain M173I and human PP1Ca | Descriptor: | GLYCEROL, Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, ... | Authors: | Hauseman, Z.J, Viscomi, J, Dhembi, A, Clark, K, King, D.A, Fodor, M. | Deposit date: | 2022-02-09 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the MRAS-SHOC2-PP1C phosphatase complex. Nature, 609, 2022
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6VY0
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7BER
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![BU of 7ber by Molmil](/molmil-images/mine/7ber) | SFX structure of the MyD88 TIR domain higher-order assembly (solved, rebuilt and refined using an identical protocol to the MicroED structure of the MyD88 TIR domain higher-order assembly) | Descriptor: | Myeloid differentiation primary response protein MyD88 | Authors: | Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Darmanin, C, Kobe, B, Xu, H, Ve, T. | Deposit date: | 2020-12-24 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography. Nat Commun, 12, 2021
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6VYF
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![BU of 6vyf by Molmil](/molmil-images/mine/6vyf) | Cryo-EM structure of Plasmodium vivax hexokinase (Open state) | Descriptor: | Phosphotransferase | Authors: | Srivastava, S.S, Darling, J.E, Suryadi, J, Morris, J.C, Drew, M.E, Subramaniam, S. | Deposit date: | 2020-02-26 | Release date: | 2020-05-06 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures Iucrj, 7, 2020
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7TL8
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![BU of 7tl8 by Molmil](/molmil-images/mine/7tl8) | 1.95A resolution structure of independent phosphoglycerate mutase from S. aureus in complex with a macrocyclic peptide inhibitor (Sa-D3) | Descriptor: | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, MANGANESE (II) ION, Peptide Sa-D3 | Authors: | Liu, L, Lovell, S, Battaile, K.P, Dranchak, P, Queme, B, Aitha, M, van Neer, R.H.P, Kimura, H, Katho, T, Suga, H, Inglese, J. | Deposit date: | 2022-01-18 | Release date: | 2022-08-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Serum-Stable and Selective Backbone-N-Methylated Cyclic Peptides That Inhibit Prokaryotic Glycolytic Mutases. Acs Chem.Biol., 17, 2022
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7BGK
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![BU of 7bgk by Molmil](/molmil-images/mine/7bgk) | Native virion of Kashmir bee virus at neutral pH | Descriptor: | Structural polyprotein | Authors: | Mukhamedova, L, Plevka, P, Fuzik, T, Hrebik, D, Novacek, J. | Deposit date: | 2021-01-07 | Release date: | 2021-03-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Virion structure and in vitro genome release mechanism of dicistrovirus Kashmir bee virus. J.Virol., 95, 2021
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7TR9
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![BU of 7tr9 by Molmil](/molmil-images/mine/7tr9) | Cascade complex from type I-A CRISPR-Cas system | Descriptor: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | Authors: | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | Deposit date: | 2022-01-28 | Release date: | 2022-08-10 | Last modified: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7BEQ
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![BU of 7beq by Molmil](/molmil-images/mine/7beq) | MicroED structure of the MyD88 TIR domain higher-order assembly | Descriptor: | Myeloid differentiation primary response protein MyD88 | Authors: | Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Darmanin, C, Kobe, B, Xu, H, Ve, T. | Deposit date: | 2020-12-24 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | ELECTRON CRYSTALLOGRAPHY (3 Å) | Cite: | MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography. Nat Commun, 12, 2021
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6W0C
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![BU of 6w0c by Molmil](/molmil-images/mine/6w0c) | Open-gate KcsA soaked in 4 mM BaCl2 | Descriptor: | BARIUM ION, Fab Heavy Chain, Fab Light Chain, ... | Authors: | Rohaim, A, Gong, L, Li, J. | Deposit date: | 2020-02-29 | Release date: | 2020-07-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.556 Å) | Cite: | Open and Closed Structures of a Barium-Blocked Potassium Channel. J.Mol.Biol., 432, 2020
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8RQF
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![BU of 8rqf by Molmil](/molmil-images/mine/8rqf) | Cryo-EM structure of human NTCP-Bulevirtide complex | Descriptor: | Fab-specific nanobody, Heavy chain of Fab3, Light chain of Fab3, ... | Authors: | Liu, H, Zakrzewicz, D, Nosol, K, Irobalieva, R.N, Mukherjee, S, Bang-Soerensen, R, Goldmann, N, Kunz, S, Rossi, L, Kossiakoff, A.A, Urban, S, Glebe, D, Geyer, J, Locher, K.P. | Deposit date: | 2024-01-18 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Cryo-EM structure of human NTCP-Bulevirtide complex To Be Published
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