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PDB: 42550 件

5FWR
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Breaking down the wall: mutation of the tyrosine gate of the universal Escherichia coli fimbrial adhesin FimH
分子名称: FimH, biphenyl-4-yl alpha-D-mannopyranoside
著者Bouckaert, J.
登録日2016-02-21
公開日2016-11-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.
IUCrJ, 4, 2017
4PV4
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Proline aminopeptidase P II from Yersinia pestis
分子名称: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ...
著者Osipiuk, J, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-03-14
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Proline aminopeptidase P II from Yersinia pestis
To be Published
1XM6
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Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R)-Mesopram
分子名称: (5R)-5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-oxazolidin-2-one, MAGNESIUM ION, ZINC ION, ...
著者Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
登録日2004-10-01
公開日2004-12-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
8GQJ
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Structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, NONAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ...
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
5FAK
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Crystal structure of Double Mutant S12T and N87T of Adenosine/Methylthioadenosine Phosphorylase from Schistosoma mansoni in complex with Adenine
分子名称: ADENINE, Methylthioadenosine phosphorylase, SULFATE ION
著者Torini, J.R, Brandao-Neto, J, DeMarco, R, Pereira, H.M.
登録日2015-12-11
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.
PLoS Negl Trop Dis, 10, 2016
4R96
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Structure of a Llama Glama Fab 48A2 against human cMet
分子名称: Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain
著者Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I.
登録日2014-09-03
公開日2015-06-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.
MAbs, 7, 2015
8GQF
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Crystal structure of Thiolase
分子名称: GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
5FR7
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Erwinia amylovora AmyR amylovoran repressor, a member of the YbjN protein family
分子名称: AMYR
著者Bartho, J.D, Bellini, D, Wuerges, J, Demitri, N, Walsh, M, Benini, S.
登録日2015-12-16
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of Erwinia amylovora AmyR, a member of the YbjN protein family, shows similarity to type III secretion chaperones but suggests different cellular functions.
PLoS ONE, 12, 2017
8GQH
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Structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQN
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X-ray structure of thiolase with CoA
分子名称: COENZYME A, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQL
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X-ray structure of Thiolase from Pseudomonas aeruginosa PAO1
分子名称: GLYCEROL, Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
5G0A
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The crystal structure of a S-selective transaminase from Bacillus megaterium
分子名称: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PYRIDOXAL-5'-PHOSPHATE, ...
著者van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W.
登録日2016-03-17
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases
Biochemistry, 55, 2016
1XOR
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BU of 1xor by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Zardaverine
分子名称: 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE, MAGNESIUM ION, ZINC ION, ...
著者Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
登録日2004-10-06
公開日2004-12-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
8GQG
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Crystal structure of Thioloase from Pseudomonas aeruginosa PAO1
分子名称: Thiolase
著者Hong, J, Son, H.F, Kim, K.J.
登録日2022-08-30
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
1X7A
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Porcine Factor IXa Complexed to 1-{3-[amino(imino)methyl]phenyl}-N-[4-(1H-benzimidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
分子名称: 1-{3-[AMINO(IMINO)METHYL]PHENYL}-N-[4-(1H-BENZIMIDAZOL-1-YL)-2-FLUOROPHENYL]-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE, Coagulation Factor IX, light chain, ...
著者Alexander, R.S, Smallwood, A.M, Smallheer, J.M, Wang, J, Wang, S, Nakajima, S, Rossi, K.A, Barbera, F, Burdick, D, Luettgen, J.M.
登録日2004-08-13
公開日2005-08-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa
Bioorg.Med.Chem.Lett., 14, 2004
8G91
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LaM domain of human LARP1 in complex with Rp phosphorothioate isomer of AAAAA(SRA) RNA
分子名称: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
著者Kozlov, G, Jiang, J, Gehring, K.
登録日2023-02-20
公開日2024-04-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
8G90
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LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA
分子名称: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
著者Kozlov, G, Jiang, J, Gehring, K.
登録日2023-02-20
公開日2024-04-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
4QPK
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1.7 Angstrom Structure of a Bacterial Phosphotransferase
分子名称: GLYCEROL, PHOSPHATE ION, PHOSPHOTRANSFERASE, ...
著者Willett, J.W, Crosson, S, Herrou, J.
登録日2014-06-23
公開日2015-07-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen.
Proc.Natl.Acad.Sci.USA, 112, 2015
1XAI
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CRYSTAL STRUCTURE OF STAPHLYOCOCCUS AUREUS 3-DEHYDROQUINATE SYNTHASE (DHQS) IN COMPLEX WITH ZN2+, NAD+ AND CARBAPHOSPHONATE
分子名称: 3-dehydroquinate synthase, ZINC ION, [1R-(1ALPHA,3BETA,4ALPHA,5BETA)]-5-(PHOSPHONOMETHYL)-1,3,4-TRIHYDROXYCYCLOHEXANE-1-CARBOXYLIC ACID
著者Nichols, C.E, Ren, J, Leslie, K, Dhaliwal, B, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K.
登録日2004-08-25
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Comparison of ligand induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases.
J.Mol.Biol., 343, 2004
1A5T
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CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III
分子名称: DELTA PRIME, ZINC ION
著者Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J.
登録日1998-02-18
公開日1998-05-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 91, 1997
8GIS
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Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.5mM Mn2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
著者Wu, S, Sohn, J.
登録日2023-03-14
公開日2024-04-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
8GIR
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Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.2mM Mn2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
著者Wu, S, Sohn, J.
登録日2023-03-14
公開日2024-04-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
8GIO
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Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.1mM Mn2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
著者Wu, S, Sohn, J.
登録日2023-03-14
公開日2024-04-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
1XU8
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The 2.8 A structure of a tumour suppressing serpin
分子名称: Maspin, SULFATE ION
著者Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C.
登録日2004-10-25
公開日2005-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
3MW6
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Crystal structure of NMB1681 from Neisseria meningitidis MC58, a FinO-like RNA chaperone
分子名称: GLYCEROL, uncharacterized protein NMB1681
著者Tan, K, Zhou, M, Duggan, E, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-05-05
公開日2010-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.209 Å)
主引用文献N. meningitidis 1681 is a member of the FinO family of RNA chaperones.
Rna Biol., 7, 2010

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