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PDB: 42550 件

3LC6
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The alternative conformation structure of isocitrate dehydrogenase kinase/phosphatase from E. Coli
分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ...
著者Zheng, J, Jia, Z.
登録日2010-01-09
公開日2010-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
8HDK
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Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (minor class in symmetry)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S.
登録日2022-11-04
公開日2023-03-29
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
Nat.Struct.Mol.Biol., 30, 2023
1WC2
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Beta-1,4-D-endoglucanase Cel45A from blue mussel Mytilus edulis at 1.2A
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, ENDOGLUCANASE
著者Jakobsson, E, Mahdi, S, Kleywegt, G.J, Stahlberg, J.
登録日2004-11-08
公開日2006-05-24
最終更新日2021-12-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Glucomannan and beta-glucan degradation by Mytilus edulis Cel45A: Crystal structure and activity comparison with GH45 subfamily A, B and C.
Carbohydr Polym, 277, 2022
5D46
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Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination
分子名称: ACETATE ION, DNA (5'-D(*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*C)-3'), ...
著者Loc'h, J, Rosario, S, Delarue, M.
登録日2015-08-07
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination.
Structure, 24, 2016
5DGG
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Central domain of uncharacterized Lpg1148 protein from Legionella pneumophila
分子名称: CHLORIDE ION, Uncharacterized protein
著者Osipiuk, J, Evdokimova, E, Yim, V, Joachimiak, A, Ensminger, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-08-27
公開日2015-09-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila.
Mol. Syst. Biol., 12, 2016
4OD1
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Crystal structure of human Fab CAP256-VRC26.03, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.03 heavy chain, CAP256-VRC26.03 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
3Q6G
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Crystal structure of Fab of rhesus mAb 2.5B specific for quaternary neutralizing epitope of HIV-1 gp120
分子名称: Heavy chain of Fab of rhesus mAb 2.5B, Light chain of Fab of rhesus mAb 2.5B
著者Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P.
登録日2010-12-31
公開日2011-05-25
最終更新日2013-03-20
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
5DHQ
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Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a novel inhibitor
分子名称: 8-[(2-{[2-(3-bromophenyl)ethyl]amino}-2-oxoethyl)sulfanyl]adenosine, CITRIC ACID, GLYCEROL, ...
著者Gelin, M, Paoletti, J, Assairi, L, Huteau, V, Pochet, S, Labesse, G.
登録日2015-08-31
公開日2016-09-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.
Eur.J.Med.Chem., 124, 2016
5DIN
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Structural Basis for the Indispensable Role of a Unique Zinc Finger Motif in LNX2 Ubiquitination
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ligand of Numb protein X 2, ZINC ION
著者Sivaraman, J, Nayak, D.
登録日2015-09-01
公開日2015-10-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.864 Å)
主引用文献Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination.
Oncotarget, 6, 2015
5DIR
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membrane protein at 2.8 Angstroms
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Globomycin, Lipoprotein signal peptidase
著者Vogeley, L, El Arnaout, T, Bailey, J, Boland, C, Caffrey, M.
登録日2015-09-01
公開日2016-03-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin.
Science, 351, 2016
8H1C
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Cryo-EM structure of Oryza sativa plastid glycyl-tRNA synthetase in complex with two tRNAs (one in tRNA binding state and the other in tRNA locked state)
分子名称: Glycine--tRNA ligase, tRNA(gly) (74-MER)
著者Yu, Z, Wu, Z, Li, Y, Lu, G, Lin, J.
登録日2022-10-02
公開日2023-04-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase.
Nucleic Acids Res., 51, 2023
5DRU
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Structure of His387Ala mutant of the propionaldehyde dehydrogenase from the Clostridium phytofermentans fucose utilisation bacterial microcompartment
分子名称: Aldehyde Dehydrogenase, SULFATE ION
著者Tuck, L.R, Altenbach, K, Fu, A.T, Crawshaw, A.D, Campopiano, D.J, Clarke, D.J, Marles-Wright, J.
登録日2015-09-16
公開日2016-03-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.083 Å)
主引用文献Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans.
Sci Rep, 6, 2016
1ACW
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SOLUTION NMR STRUCTURE OF P01, A NATURAL SCORPION PEPTIDE STRUCTURALLY ANALOGOUS TO SCORPION TOXINS SPECIFIC FOR APAMIN-SENSITIVE POTASSIUM CHANNEL, 25 STRUCTURES
分子名称: NATURAL SCORPION PEPTIDE P01
著者Blanc, E, Fremont, V, Sizun, P, Meunier, S, Van Rietschoten, J, Thevand, A, Bernassau, J.M, Darbon, H.
登録日1997-02-10
公開日1997-04-01
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of P01, a natural scorpion peptide structurally analogous to scorpion toxins specific for apamin-sensitive potassium channel.
Proteins, 24, 1996
4O8U
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Structure of PF2046
分子名称: Uncharacterized protein PF2046
著者Su, J, Liu, Z.-J.
登録日2013-12-30
公開日2014-04-30
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献Crystal structure of a novel non-Pfam protein PF2046 solved using low resolution B-factor sharpening and multi-crystal averaging methods
Protein Cell, 1, 2010
5DLL
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Aminopeptidase N (pepN) from Francisella tularensis subsp. tularensis SCHU S4
分子名称: Aminopeptidase N, CHLORIDE ION, PHOSPHATE ION, ...
著者Borek, D, Raczynska, J, Dubrovska, I, Grimshaw, S, Minasov, G, Shuvalova, L, Kwon, K, Anderson, W.F, Otwinowski, Z, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-09-07
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Aminopeptidase N (pepN) from Francisella tularensis subsp. tularensis SCHU S4
To Be Published
4O7D
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Crystal structure of human glutaminase in complex DON
分子名称: 5-OXO-L-NORLEUCINE, Glutaminase kidney isoform, mitochondrial
著者Thangavelu, K, Sivaraman, J.
登録日2013-12-24
公開日2014-04-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA)
Sci Rep, 4, 2014
121D
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MOLECULAR STRUCTURE OF THE A-TRACT DNA DODECAMER D(CGCAAATTTGCG) COMPLEXED WITH THE MINOR GROOVE BINDING DRUG NETROPSIN
分子名称: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), NETROPSIN
著者Tabernero, L, Verdaguer, N, Coll, M, Fita, I, Van Der Marel, G.A, Van Boom, J.H, Rich, A, Aymami, J.
登録日1993-04-14
公開日1994-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin.
Biochemistry, 32, 1993
4O7N
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SAICAR synthetase (Type-2) in complex with ADP
分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Manjunath, K, Jeyakanthan, J, Sekar, K.
登録日2013-12-26
公開日2014-12-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献SAICAR synthetase (Type-2) in complex with ADP
To be Published
1WUG
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complex structure of PCAF bromodomain with small chemical ligand NP1
分子名称: Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE
著者Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M.
登録日2004-12-07
公開日2005-08-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
1WUM
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Complex structure of PCAF bromodomain with small chemical ligand NP2
分子名称: Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-2-NITROBENZENAMINE
著者Zeng, L, Li, J, Muller, M, Yan, S, Mujtaba, S, Pan, C, Wang, Z, Zhou, M.M.
登録日2004-12-08
公開日2005-08-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
J.Am.Chem.Soc., 127, 2005
4OBR
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Crystal structure of human alpha-L-iduronidase complex with alpha-L-iduronic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, ...
著者Bie, H.Y, Yin, J, He, X, Kermode, A.R, James, M.N.G.
登録日2014-01-07
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Crystal structure of human alpha-L-iduronidase complex with alpha-L-iduronic acid
To be Published
3QJ6
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The crystal structure of PWWP domain of human Hepatoma-derived growth factor 2 in complex with H3K79me3 peptide
分子名称: H3K79me3, Hepatoma-derived growth factor-related protein 2, SULFATE ION, ...
著者Zeng, H, Amaya, M.F, Tempel, W, Walker, J.R, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2011-01-28
公開日2011-02-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
1WC4
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Soluble adenylyl cyclase CyaC from S. platensis in complex with alpha, beta-methylene-ATP and Europium
分子名称: ADENYLATE CYCLASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, EUROPIUM (III) ION
著者Steegborn, C, Litvin, T.N, Levin, L.R, Buck, J, Wu, H.
登録日2004-11-08
公開日2004-12-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bicarbonate Activation of Adenylyl Cyclase Via Promotion of Catalytic Active Site Closure and Metal Recruitment
Nat.Struct.Mol.Biol., 12, 2005
4OMF
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The F420-reducing [NiFe]-hydrogenase complex from Methanothermobacter marburgensis, the first X-ray structure of a group 3 family member
分子名称: CHLORIDE ION, F420-reducing hydrogenase, subunit alpha, ...
著者Vitt, S, Ma, K, Warkentin, E, Moll, J, Pierik, A, Shima, S, Ermler, U.
登録日2014-01-27
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The F420-Reducing [NiFe]-Hydrogenase Complex from Methanothermobacter marburgensis, the First X-ray Structure of a Group 3 Family Member.
J.Mol.Biol., 426, 2014
4OR6
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Structure of Influenza B PB2 cap-binding domain with Q325F mutation complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Polymerase basic protein 2
著者Liu, Y, Fan, J, Zheng, X.
登録日2014-02-11
公開日2015-02-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献The crystal structure of the PB2 cap-binding domain of influenza B virus reveals a novel cap recognition mechanism.
J.Biol.Chem., 290, 2015

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