9B1U
 
 | | Crystal structure of PqqT with PQQ bound | | 分子名称: | PYRROLOQUINOLINE QUINONE, Putative ABC transporter periplasmic solute-binding protein, SODIUM ION | | 著者 | Boggs, D, Bruchs, A, Thompson, P, Olshansky, L, Bridwell-Rabb, J. | | 登録日 | 2024-03-13 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structure-driven development of a biomimetic rare earth artificial metalloprotein.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9B1V
 | | Crystal structure of PqqT with PQQ and Gd3+ bound | | 分子名称: | 1,2-ETHANEDIOL, GADOLINIUM ION, PYRROLOQUINOLINE QUINONE, ... | | 著者 | Boggs, G.D, Bruchs, A.T, Thompson, P.J, Olshansky, L, Bridwell-Rabb, J. | | 登録日 | 2024-03-13 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure-driven development of a biomimetic rare earth artificial metalloprotein.
Proc.Natl.Acad.Sci.USA, 121, 2024
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4OUO
 | | anti-Bla g 1 scFv | | 分子名称: | CHLORIDE ION, SULFATE ION, anti Bla g 1 scFv | | 著者 | Mueller, G.A, Ankney, J.A, Glesner, J, Khurana, T, Edwards, L.L, Pedersen, L.C, Perera, L, Slater, J.E, Pomes, A, London, R.E. | | 登録日 | 2014-02-18 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of an anti-Bla g 1 scFv: Epitope mapping and cross-reactivity.
Mol.Immunol., 59, 2014
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8H9D
 | | Crystal structure of Cas12a protein | | 分子名称: | Cas12A, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3'), ... | | 著者 | Jianwei, L, Jobichen, C, Sivaraman, J. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage.
Plos Biol., 21, 2023
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7URX
 | | SJ25C1 Fab in complex with soluble CD19 | | 分子名称: | B-lymphocyte antigen CD19, SJ25C1 Fab heavy chain, SJ25C1 Fab light chain | | 著者 | Meyerson, J, He, C. | | 登録日 | 2022-04-22 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | CD19 CAR antigen engagement mechanisms and affinity tuning.
Sci Immunol, 8, 2023
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4OZR
 | | Crystal structure of the ligand binding domains of the Bovicola ovis ecdysone receptor EcR/USP heterodimer (methylene lactam crystal) | | 分子名称: | Ecdysone receptor, Retinoid X receptor | | 著者 | Ren, B, Peat, T.S, Streltsov, V.A, Pollard, M, Fernley, R, Grusovin, J, Seabrook, S, Pilling, P, Phan, T, Lu, L, Lovrecz, G.O, Graham, L.D, Hill, R.J. | | 登録日 | 2014-02-18 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits.
Acta Crystallogr.,Sect.D, 70, 2014
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5DGW
 | | Crystal Structure of HIV-1 Protease Inhibitor GRL-105-11A Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand | | 分子名称: | (3R,3aS,4S,7aS)-3-(ethylamino)hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, Pol protein, ... | | 著者 | Agniswamy, J, Wang, Y.-F, Weber, I.T. | | 登録日 | 2015-08-28 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands.
Org.Biomol.Chem., 13, 2015
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8H68
 | | Crystal structure of Caenorhabditis elegans NMAD-1 in complex with NOG and Mg(II) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Shi, Y, Ding, J, Yang, H. | | 登録日 | 2022-10-16 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Caenorhabditis elegans NMAD-1 functions as a demethylase for actin.
J Mol Cell Biol, 15, 2023
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1WPX
 | | Crystal structure of carboxypeptidase Y inhibitor complexed with the cognate proteinase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase Y, Carboxypeptidase Y inhibitor, ... | | 著者 | Mima, J, Hayashida, M, Fujii, T, Narita, Y, Hayashi, R, Ueda, M, Hata, Y. | | 登録日 | 2004-09-14 | | 公開日 | 2005-03-01 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of the carboxypeptidase y inhibitor i(c) in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction
J.Mol.Biol., 346, 2005
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5DHS
 | | Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a novel inhibitor | | 分子名称: | 5'-azido-5'-deoxy-8-[(2-{[2-(3-ethynylphenyl)ethyl]amino}-2-oxoethyl)sulfanyl]adenosine, CITRIC ACID, GLYCEROL, ... | | 著者 | Gelin, M, Paoletti, J, Assairi, L, Huteau, V, Pochet, S, Labesse, G. | | 登録日 | 2015-08-31 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.
Eur.J.Med.Chem., 124, 2016
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8HIL
 | | A cryo-EM structure of B. oleracea RNA polymerase V at 3.57 Angstrom | | 分子名称: | DNA-dependent RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, DNA-directed RNA polymerase subunit, ... | | 著者 | Du, X, Xie, G, Hu, H, Du, J. | | 登録日 | 2022-11-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | Structure and mechanism of the plant RNA polymerase V.
Science, 379, 2023
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5CRU
 | | Crystal structure of the Bro domain of HD-PTP | | 分子名称: | Tyrosine-protein phosphatase non-receptor type 23 | | 著者 | Lee, J, Ku, B, Kim, S.J. | | 登録日 | 2015-07-23 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0
Plos One, 11, 2016
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8HBD
 | | Cryo-EM structure of IRL1620-bound ETBR-Gi complex | | 分子名称: | Endothelin receptor type B,Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Yuan, Q, Ji, Y, Jiang, Y, Duan, J, Xu, H.E. | | 登録日 | 2022-10-28 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
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7URV
 | | FMC63 scFv in complex with soluble CD19 | | 分子名称: | B-lymphocyte antigen CD19, FMC63 single-chain variable fragment | | 著者 | Meyerson, J, He, C. | | 登録日 | 2022-04-22 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | CD19 CAR antigen engagement mechanisms and affinity tuning.
Sci Immunol, 8, 2023
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5CSL
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8HCX
 | | Cryo-EM structure of Endothelin1-bound ETBR-Gq complex | | 分子名称: | Endothelin receptor type B,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. | | 登録日 | 2022-11-03 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
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8HIM
 | | A cryo-EM structure of B. oleracea RNA polymerase V elongation complex at 2.73 Angstrom | | 分子名称: | DNA (34-MER), DNA-directed RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, ... | | 著者 | Hu, H, Xie, G, Du, X, Du, J. | | 登録日 | 2022-11-21 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure and mechanism of the plant RNA polymerase V.
Science, 379, 2023
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8UZT
 | | Mitochondrial single-stranded binding protein bound to DNA | | 分子名称: | GLYCEROL, SODIUM ION, Single-stranded DNA-binding protein, ... | | 著者 | Riccio, A.A, Pedersen, L.C, Bouvette, J, Borgnia, J.M, Copeland, W.C. | | 登録日 | 2023-11-16 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase gamma.
Nucleic Acids Res., 2024
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8HCQ
 | | Cryo-EM structure of endothelin1-bound ETAR-Gq complex | | 分子名称: | Endothelin-1, Endothelin-1 receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. | | 登録日 | 2022-11-02 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural basis of peptide recognition and activation of endothelin receptors.
Nat Commun, 14, 2023
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8ZSB
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8ZSZ
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1WXR
 | | Crystal structure of Heme Binding protein, an autotransporter hemoglobine protease from pathogenic Escherichia coli | | 分子名称: | haemoglobin protease | | 著者 | Otto, B.R, Sijbrandi, R, Luirink, J, Oudega, B, Heddle, J.G, Mizutani, K, Park, S.-Y, Tame, J.R.H. | | 登録日 | 2005-01-31 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of heme binding protein, an autotransporter hemoglobin protease from pathogenic escherichia coli
J.Biol.Chem., 280, 2005
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7UYX
 | | Structure of bacteriophage PA1c gp2 | | 分子名称: | Bacteriophage PA1C gp2 | | 著者 | Enustun, E, Deep, A, Gu, Y, Nguyen, K, Chaikeeratisak, V, Armbruster, E, Ghassemian, M, Pogliano, J, Corbett, K.D. | | 登録日 | 2022-05-07 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Identification of the bacteriophage nucleus protein interaction network.
Nat.Struct.Mol.Biol., 30, 2023
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8HD6
 | | The relaxed pre-Tet-S1 state of G264A mutated Tetrahymena group I intron with 6nt 3'/5'-exon and 2-aminopurine nucleoside | | 分子名称: | MAGNESIUM ION, SPERMIDINE, The relaxed pre-Tet-S1 state molecule of co-transcriptional folded G264A mutant Tetrahymena group I intron with 6nt 3'/5'-exon and 2-aminopurine nucleoside | | 著者 | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | | 登録日 | 2022-11-03 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing
Nat Catal, 2023
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8HD7
 | | The intermediate pre-Tet-S1 state of G264A mutated Tetrahymena group I intron with 6nt 3'/5'-exon and 2-aminopurine nucleoside | | 分子名称: | MAGNESIUM ION, SPERMIDINE, The intermediate pre-Tet-S1 state molecule of co-transcriptional folded G264A mutant Tetrahymena group I intron with 6nt 3'/5'-exon and 2-aminopurine nucleoside | | 著者 | Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z. | | 登録日 | 2022-11-03 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing
Nat Catal, 2023
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