4EYQ
 
 | | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris HaA2 in complex with caffeic acid/3-(4-HYDROXY-PHENYL)PYRUVIC ACID | | 分子名称: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, CAFFEIC ACID, Extracellular ligand-binding receptor | | 著者 | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2012-05-01 | | 公開日 | 2012-05-30 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids.
Proteins, 81, 2013
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7MWL
 | | The TAM domain of BAZ2A in complex with a 12mer mCG DNA | | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), GLYCEROL | | 著者 | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2021-05-17 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The TAM domain of BAZ2A in complex with a 12mer mCG DNA
To Be Published
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3CXP
 | | Crystal structure of human glucosamine 6-phosphate N-acetyltransferase 1 mutant E156A | | 分子名称: | CHLORIDE ION, Glucosamine 6-phosphate N-acetyltransferase | | 著者 | Wang, J, Liu, X, Li, L.-F, Su, X.-D. | | 登録日 | 2008-04-25 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1
Febs Lett., 582, 2008
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5CKR
 | | Crystal Structure of MraY in complex with Muraymycin D2 | | 分子名称: | Muraymycin D2, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | 著者 | Lee, S.Y, Chung, B.C, Mashalidis, E.H, Tanino, T, Kim, M, Hong, J, Ichikawa, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.
Nature, 533, 2016
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5CP3
 | | Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides in Complex with Sulfathiazole | | 分子名称: | 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, CALCIUM ION, GLYCEROL, ... | | 著者 | Wang, Z, Shen, J, Li, C, Li, Y, Wen, K, Yu, X, Zhang, X. | | 登録日 | 2015-07-21 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.
Anal. Chem., 91, 2019
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7MEM
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3D0M
 | | X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex | | 分子名称: | RNA (5'-R(*GP*UP*GP*GP*UP*CP*UP*GP*AP*UP*GP*AP*GP*GP*CP*C)-3'), SULFATE ION | | 著者 | Rypniewski, W, Adamiak, D.A, Milecki, J, Adamiak, R.W. | | 登録日 | 2008-05-02 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Noncanonical G(syn)-G(anti) base pairs stabilized by sulphate anions in two X-ray structures of the (GUGGUCUGAUGAGGCC) RNA duplex.
Rna, 14, 2008
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5CNP
 | | X-ray crystal structure of Spermidine n1-acetyltransferase from Vibrio cholerae. | | 分子名称: | ISOPROPYL ALCOHOL, MAGNESIUM ION, Spermidine N(1)-acetyltransferase | | 著者 | Osipiuk, J, VOLKART, L, MOY, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2015-07-17 | | 公開日 | 2015-07-29 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG.
J.Mol.Biol., 427, 2015
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5BXY
 | | Crystal structure of RNA methyltransferase from Salinibacter ruber in complex with S-Adenosyl-L-homocysteine | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, RNA methyltransferase, ... | | 著者 | Handing, K.B, LaRowe, C, Shabalin, I.G, Stead, M, Hillerich, B.S, Ahmed, M, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2015-06-09 | | 公開日 | 2015-07-01 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of RNA methylase family protein from Salinibacterruber in complex with S-Adenosyl-L-homocysteine.
to be published
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3D5O
 | | Structural recognition and functional activation of FcrR by innate pentraxins | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Low affinity immunoglobulin gamma Fc region receptor II-a, ... | | 著者 | Lu, J, Marnell, L.L, Marjon, K.D, Mold, C, Du Clos, T.W, Sun, P.D. | | 登録日 | 2008-05-16 | | 公開日 | 2008-11-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural recognition and functional activation of FcgammaR by innate pentraxins.
Nature, 456, 2008
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3D3F
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3D3T
 | | Crystal Structure of HIV-1 CRF01_AE in complex with the substrate p1-p6 | | 分子名称: | HIV-1 protease, P1-P6 SUBSTRATE PEPTIDE | | 著者 | Bandaranayake, R.M, Prabu-Jeyabalan, M, Kakizawa, J, Sugiura, W, Schiffer, C.A. | | 登録日 | 2008-05-12 | | 公開日 | 2008-07-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural analysis of human immunodeficiency virus type 1 CRF01_AE protease in complex with the substrate p1-p6.
J.Virol., 82, 2008
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5E8C
 | | pseudorabies virus nuclear egress complex, pUL31, pUL34 | | 分子名称: | CHLORIDE ION, UL31, UL34 protein, ... | | 著者 | Zeev-Ben-Mordehai, T, Cheleski, J, Whittle, C, El Omari, K, Harlos, K, Hagen, C, Klupp, B, Mettenleiter, T.C, Gruenewald, K. | | 登録日 | 2015-10-14 | | 公開日 | 2015-12-23 | | 最終更新日 | 2016-01-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling.
Cell Rep, 13, 2015
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5E8L
 | | Crystal structure of geranylgeranyl pyrophosphate synthase 11 from Arabidopsis thaliana | | 分子名称: | Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic | | 著者 | Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. | | 登録日 | 2015-10-14 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.807 Å) | | 主引用文献 | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants.
Mol Plant, 9, 2016
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3CEQ
 | | The TPR domain of Human Kinesin Light Chain 2 (hKLC2) | | 分子名称: | Kinesin light chain 2 | | 著者 | Zhu, H, Shen, Y, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-02-29 | | 公開日 | 2008-08-12 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The TPR domain of Human Kinesin Light Chain 2 (hKLC2)
To be Published
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7M4T
 | | Menin bound to M-1121 | | 分子名称: | Menin, methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate, praseodymium triacetate | | 著者 | Stuckey, J. | | 登録日 | 2021-03-22 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression.
J.Med.Chem., 64, 2021
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3CIG
 | | Crystal structure of mouse TLR3 ectodomain | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R. | | 登録日 | 2008-03-11 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
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3CK2
 | | Crystal structure of conserved uncharacterized protein (predicted phosphoesterase COG0622) from Streptococcus pneumoniae TIGR4 | | 分子名称: | CHLORIDE ION, Conserved uncharacterized protein (predicted phosphoesterase COG0622), MANGANESE (II) ION, ... | | 著者 | Nocek, B, Zhou, M, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-03-14 | | 公開日 | 2008-04-01 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of conserved uncharacterized protein (predicted phosphoesterase COG0622) from Streptococcus pneumoniae TIGR4.
To be Published
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5DL9
 | | Structure of Tetragonal Lysozyme in complex with Iodine solved by UWO Students | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, IODIDE ION, ... | | 著者 | Bednarski, R, Cirricione, N, Greco, A, Hodgson, R, Kent, S, McGowan, J, Notherm, B, Patt, M, Vue, L, Bianchetti, C.M. | | 登録日 | 2015-09-04 | | 公開日 | 2015-09-16 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structure of Tetragonal Lysozyme in complex with Iodine solved by UWO Students
To Be Published
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3CKZ
 | | N1 Neuraminidase H274Y + Zanamivir | | 分子名称: | CALCIUM ION, Neuraminidase, ZANAMIVIR | | 著者 | Colllins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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1VSG
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3CO5
 | | Crystal structure of sigma-54 interaction domain of putative transcriptional response regulator from Neisseria gonorrhoeae | | 分子名称: | BETA-MERCAPTOETHANOL, Putative two-component system transcriptional response regulator | | 著者 | Osipiuk, J, Hendricks, R, Bigelow, L, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-03-27 | | 公開日 | 2008-04-08 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray crystal structure of Sigma-54 interaction domain of putative transcriptional response regulator from Neisseria gonorrhoeae.
To be Published
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3CP7
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7MDZ
 | | 80S rabbit ribosome stalled with benzamide-CHX | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ... | | 著者 | Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B. | | 登録日 | 2021-04-06 | | 公開日 | 2021-09-01 | | 最終更新日 | 2021-09-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.
J.Am.Chem.Soc., 143, 2021
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5DQC
 | | Co-crystal of BACE1 with compound 0211 | | 分子名称: | Beta-secretase 1, N-[(2S,3R)-3-hydroxy-4-({(2S,3S)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | | 著者 | Ghosh, A.K, Bhavanam, S.R, Yen, T.-C, Cardenas, E.L, Rao, K.V, Downs, D, Huang, X, Tang, J, Mescar, A.D. | | 登録日 | 2015-09-14 | | 公開日 | 2016-02-17 | | 最終更新日 | 2016-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4651 Å) | | 主引用文献 | Design of Potent and Highly Selective Inhibitors for Human beta-Secretase 2 (Memapsin 1), a Target for Type 2 Diabetes.
Chem Sci, 7, 2016
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