5CKR
Crystal Structure of MraY in complex with Muraymycin D2
Summary for 5CKR
| Entry DOI | 10.2210/pdb5ckr/pdb |
| Descriptor | Phospho-N-acetylmuramoyl-pentapeptide-transferase, Muraymycin D2 (3 entities in total) |
| Functional Keywords | alpha-helical, pnpt superfamily, phospho-murnac-pentapeptide translocase, membrane protein, bacterial cell wall, synthesis, natural product inhibitor, transferase-antibiotic complex, transferase/antibiotic |
| Biological source | Aquifex aeolicus (strain VF5) |
| Total number of polymer chains | 1 |
| Total formula weight | 41870.63 |
| Authors | Lee, S.Y.,Chung, B.C.,Mashalidis, E.H.,Tanino, T.,Kim, M.,Hong, J.,Ichikawa, S. (deposition date: 2015-07-15, release date: 2016-03-02, Last modification date: 2023-09-27) |
| Primary citation | Chung, B.C.,Mashalidis, E.H.,Tanino, T.,Kim, M.,Matsuda, A.,Hong, J.,Ichikawa, S.,Lee, S.Y. Structural insights into inhibition of lipid I production in bacterial cell wall synthesis. Nature, 533:557-560, 2016 Cited by PubMed: 27088606DOI: 10.1038/nature17636 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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