5CKR

Crystal Structure of MraY in complex with Muraymycin D2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008360	biological_process	regulation of cell shape
A	0008963	molecular_function	phospho-N-acetylmuramoyl-pentapeptide-transferase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016020	cellular_component	membrane
A	0016740	molecular_function	transferase activity
A	0016780	molecular_function	phosphotransferase activity, for other substituted phosphate groups
A	0042802	molecular_function	identical protein binding
A	0044038	biological_process	cell wall macromolecule biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051301	biological_process	cell division
A	0051992	molecular_function	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue 57M A 401

Chain	Residue
A	LYS70
A	MET263
A	GLY264
A	ASP265
A	SER268
A	VAL302
A	GLN305
A	ARG320
A	ALA321
A	PRO322
A	HIS325
A	THR75
A	HOH503
A	ASN190
A	ASP193
A	GLY194
A	LEU195
A	ASP196
A	ASN255
A	PHE262

---

Functional Information from PROSITE/UniProt

site_id	PS01347
Number of Residues	13
Details	MRAY_1 MraY family signature 1. KkyTPTMGGIvIL

Chain	Residue	Details
A	LYS70-LEU82

---

site_id	PS01348
Number of Residues	12
Details	MRAY_2 MraY family signature 2. NavNlTDGLDGL

Chain	Residue	Details
A	ASN187-LEU198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=Helix 1","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	17
Details	Transmembrane: {"description":"Helical; Name=Helix 2","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	44
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=Helix 3","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	40
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=Helix 4","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=Helix 5","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	20
Details	Transmembrane: {"description":"Helical; Name=Helix 6","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=Helix 7","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	15
Details	Transmembrane: {"description":"Helical; Name=Helix 8","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	25
Details	Transmembrane: {"description":"Helical; Name=Helix 9","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=Helix 10","evidences":[{"source":"PubMed","id":"23990562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27088606","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CKR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---