5W1V
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![BU of 5w1v by Molmil](/molmil-images/mine/5w1v) | Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex | 分子名称: | Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... | 著者 | Gras, S, Walpole, N, Farenc, C, Rossjohn, J. | 登録日 | 2017-06-04 | 公開日 | 2017-10-04 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors. J. Biol. Chem., 292, 2017
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5VKB
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![BU of 5vkb by Molmil](/molmil-images/mine/5vkb) | Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and argininamide | 分子名称: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININEAMIDE, ... | 著者 | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | 登録日 | 2017-04-21 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.139 Å) | 主引用文献 | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
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1A3R
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![BU of 1a3r by Molmil](/molmil-images/mine/1a3r) | |
3UA8
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![BU of 3ua8 by Molmil](/molmil-images/mine/3ua8) | |
3TQW
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![BU of 3tqw by Molmil](/molmil-images/mine/3tqw) | Structure of a ABC transporter, periplasmic substrate-binding protein from Coxiella burnetii | 分子名称: | METHIONINE, Methionine-binding protein, SULFATE ION | 著者 | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | 登録日 | 2011-09-09 | 公開日 | 2011-09-21 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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3TRC
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![BU of 3trc by Molmil](/molmil-images/mine/3trc) | Structure of the GAF domain from a phosphoenolpyruvate-protein phosphotransferase (ptsP) from Coxiella burnetii | 分子名称: | PHOSPHATE ION, Phosphoenolpyruvate-protein phosphotransferase, SODIUM ION | 著者 | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | 登録日 | 2011-09-09 | 公開日 | 2011-09-28 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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5VJD
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![BU of 5vjd by Molmil](/molmil-images/mine/5vjd) | Class II fructose-1,6-bisphosphate aldolase of Escherichia coli with DHAP | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase class 2, SODIUM ION, ... | 著者 | Sygusch, J, Coincon, M. | 登録日 | 2017-04-19 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 293, 2018
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3TQR
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![BU of 3tqr by Molmil](/molmil-images/mine/3tqr) | Structure of the phosphoribosylglycinamide formyltransferase (purN) in complex with CHES from Coxiella burnetii | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Phosphoribosylglycinamide formyltransferase | 著者 | Rudolph, M, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | 登録日 | 2011-09-09 | 公開日 | 2011-09-28 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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7FCL
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![BU of 7fcl by Molmil](/molmil-images/mine/7fcl) | Zebrafish SIGIRR TIR domain | 分子名称: | SIGIRR protein | 著者 | Wang, X, Zhou, J. | 登録日 | 2021-07-15 | 公開日 | 2022-07-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling Iscience, 25, 2022
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3TR2
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![BU of 3tr2 by Molmil](/molmil-images/mine/3tr2) | Structure of a orotidine 5'-phosphate decarboxylase (pyrF) from Coxiella burnetii | 分子名称: | Orotidine 5'-phosphate decarboxylase | 著者 | Cheung, J, Franklin, M, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | 登録日 | 2011-09-09 | 公開日 | 2011-09-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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3TRH
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![BU of 3trh by Molmil](/molmil-images/mine/3trh) | Structure of a phosphoribosylaminoimidazole carboxylase catalytic subunit (purE) from Coxiella burnetii | 分子名称: | Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit | 著者 | Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | 登録日 | 2011-09-09 | 公開日 | 2011-09-28 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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7FAX
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3TTH
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![BU of 3tth by Molmil](/molmil-images/mine/3tth) | Structure of the spermidine N1-acetyltransferase (speG) from Coxiella burnetii | 分子名称: | SULFATE ION, Spermidine N1-acetyltransferase | 著者 | Rudolph, M, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | 登録日 | 2011-09-14 | 公開日 | 2011-11-09 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (3.298 Å) | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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3EKH
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![BU of 3ekh by Molmil](/molmil-images/mine/3ekh) | Calcium-saturated GCaMP2 T116V/K378W mutant monomer | 分子名称: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | 著者 | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | 登録日 | 2008-09-19 | 公開日 | 2008-12-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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2XCY
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![BU of 2xcy by Molmil](/molmil-images/mine/2xcy) | Crystal structure of Aspergillus fumigatus sialidase | 分子名称: | CHLORIDE ION, EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE, ... | 著者 | Telford, J.C, Yeung, J, Xu, G, Bennet, A, Moore, M.M, Taylor, G.L. | 登録日 | 2010-04-27 | 公開日 | 2010-05-12 | 最終更新日 | 2017-06-28 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | The Aspergillus Fumigatus Sialidase is a Kdnase: Structural and Mechanistic Insights. J.Biol.Chem., 286, 2011
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6GOV
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![BU of 6gov by Molmil](/molmil-images/mine/6gov) | Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | 著者 | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | 登録日 | 2018-06-04 | 公開日 | 2019-02-13 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
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6GQO
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![BU of 6gqo by Molmil](/molmil-images/mine/6gqo) | Crystal structure of human KDR (VEGFR2) kinase domain in complex with AZD3229-analogue (compound 18) | 分子名称: | 2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{N}-(1-propan-2-ylpyrazol-4-yl)ethanamide, Vascular endothelial growth factor receptor 2 | 著者 | Ogg, D.J, Schimpl, M, Hardy, C.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. | 登録日 | 2018-06-07 | 公開日 | 2018-09-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J. Med. Chem., 61, 2018
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1Q3X
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![BU of 1q3x by Molmil](/molmil-images/mine/1q3x) | Crystal structure of the catalytic region of human MASP-2 | 分子名称: | GLYCEROL, Mannan-binding lectin serine protease 2, SODIUM ION | 著者 | Harmat, V, Gal, P, Kardos, J, Szilagyi, K, Ambrus, G, Naray-Szabo, G, Zavodszky, P. | 登録日 | 2003-08-01 | 公開日 | 2004-08-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions J.Mol.Biol., 342, 2004
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6GRP
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![BU of 6grp by Molmil](/molmil-images/mine/6grp) | Crystal Structure Of Human Transthyretin in complex with 3,5,6-trichloro-2-pyridinol (TC2P) | 分子名称: | 3,5,6-trichloro-2-pyridinol, SODIUM ION, Transthyretin | 著者 | Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E. | 登録日 | 2018-06-12 | 公開日 | 2018-07-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52, 2018
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5T5O
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7F02
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![BU of 7f02 by Molmil](/molmil-images/mine/7f02) | Cytochrome c-type biogenesis protein CcmABCD from E. coli | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7F03
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![BU of 7f03 by Molmil](/molmil-images/mine/7f03) | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7F04
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![BU of 7f04 by Molmil](/molmil-images/mine/7f04) | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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2XKB
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3EK4
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![BU of 3ek4 by Molmil](/molmil-images/mine/3ek4) | Calcium-saturated GCaMP2 Monomer | 分子名称: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | 著者 | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | 登録日 | 2008-09-18 | 公開日 | 2008-12-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design J.Biol.Chem., 284, 2009
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