1A3R

FAB FRAGMENT (ANTIBODY 8F5) COMPLEXED WITH PEPTIDE FROM HUMAN RHINOVIRUS (SEROTYPE 2) VIRAL CAPSID PROTEIN VP2 (RESIDUES 156-170)

Summary for 1A3R

• Entry DOI: 10.2210/pdb1a3r/pdb
• Descriptor: IGG2A 8F5 FAB (LIGHT CHAIN), IGG2A 8F5 FAB (HEAVY CHAIN), HUMAN RHINOVIRUS CAPSID PROTEIN VP2, ... (4 entities in total)
• Functional Keywords: immunoglobulin, antibody, rhinovirus, neutralization, continuous epitope, complex (immunoglobulin-viral peptide), viral protein-immune system complex, viral protein/immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P04936
• Total number of polymer chains: 3
• Total formula weight: 49716.09

Authors

Tormo, J.,Blaas, D.,Fita, I. (deposition date: 1998-01-23, release date: 1998-04-29, Last modification date: 2023-08-02)

• Primary citation: Tormo, J.,Blaas, D.,Parry, N.R.,Rowlands, D.,Stuart, D.,Fita, I.; Crystal structure of a human rhinovirus neutralizing antibody complexed with a peptide derived from viral capsid protein VP2.; EMBO J., 13:2247-2256, 1994; PubMed: 8194515

Experimental method

X-RAY DIFFRACTION (2.1 Å)