6GRP
Crystal Structure Of Human Transthyretin in complex with 3,5,6-trichloro-2-pyridinol (TC2P)
Summary for 6GRP
Entry DOI | 10.2210/pdb6grp/pdb |
Descriptor | Transthyretin, 3,5,6-trichloro-2-pyridinol, SODIUM ION, ... (4 entities in total) |
Functional Keywords | transthyretin, transport protein, thyroxine disrupting chemicals, tdcs, 3, 5, 6-trichloro-2-pyridinol, tc2p |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 28371.45 |
Authors | Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (deposition date: 2018-06-12, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52:11865-11874, 2018 Cited by PubMed: 30226982DOI: 10.1021/acs.est.8b03581 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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