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6GRP

Crystal Structure Of Human Transthyretin in complex with 3,5,6-trichloro-2-pyridinol (TC2P)

Summary for 6GRP
Entry DOI10.2210/pdb6grp/pdb
DescriptorTransthyretin, 3,5,6-trichloro-2-pyridinol, SODIUM ION, ... (4 entities in total)
Functional Keywordstransthyretin, transport protein, thyroxine disrupting chemicals, tdcs, 3, 5, 6-trichloro-2-pyridinol, tc2p
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight28371.45
Authors
Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (deposition date: 2018-06-12, release date: 2018-07-11, Last modification date: 2024-01-17)
Primary citationZhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E.
Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
Environ. Sci. Technol., 52:11865-11874, 2018
Cited by
PubMed: 30226982
DOI: 10.1021/acs.est.8b03581
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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