5JIQ
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![BU of 5jiq by Molmil](/molmil-images/mine/5jiq) | Crystal Structure of Human Transthyretin in Complex with 2,2',4,4'-tetrahydroxybenzophenone (BP2) | 分子名称: | GLYCEROL, SODIUM ION, Transthyretin, ... | 著者 | Begum, A, Zhang, J, Olofsson, A, Andersson, P, Sauer-Eriksson, A.E. | 登録日 | 2016-04-22 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ. Sci. Technol., 50, 2016
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6BPS
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![BU of 6bps by Molmil](/molmil-images/mine/6bps) | Crystal structure of cysteine-bound ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... | 著者 | Liu, A, Li, J, Shin, I. | 登録日 | 2017-11-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol., 14, 2018
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4YIH
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![BU of 4yih by Molmil](/molmil-images/mine/4yih) | Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PVU | 分子名称: | 1-{2-deoxy-3,5-O-[phenyl(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-[(E)-2-phosphonoethenyl]pyrimidine-2,4(1H,3H)-dione, 5'(3')-deoxyribonucleotidase, cytosolic type, ... | 著者 | Pachl, P, Rezacova, P, Brynda, J. | 登録日 | 2015-03-02 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structure-based design of a bisphosphonate 5'(3')-deoxyribonucleotidase inhibitor Medchemcomm, 6, 2015
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6Q8P
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![BU of 6q8p by Molmil](/molmil-images/mine/6q8p) | Structure of CLK1 with bound N-methyl-10-nitropyrido[3,4-g]quinazolin-2-amine | 分子名称: | Dual specificity protein kinase CLK1, POTASSIUM ION, ~{N}-methyl-10-nitro-pyrido[3,4-g]quinazolin-2-amine | 著者 | Joerger, A.C, Chatterjee, D, Schroeder, M, Tazarki, H, Zeinyeh, W, Esvan, Y.J, Khiari, J, Josselin, B, Baratte, B, Bach, S, Ruchaud, S, Anizon, F, Giraud, F, Moreau, P, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2018-12-15 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis. Eur J Med Chem, 166, 2019
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6BPV
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![BU of 6bpv by Molmil](/molmil-images/mine/6bpv) | Crystal structure of cysteine-bound ferrous form of the matured F2-Tyr157 human cysteine dioxygenase | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... | 著者 | Liu, A, Li, J, Shin, I. | 登録日 | 2017-11-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat. Chem. Biol., 14, 2018
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3SDX
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![BU of 3sdx by Molmil](/molmil-images/mine/3sdx) | Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide | 分子名称: | Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide, ... | 著者 | Clarke, A.J, Patel, O, Rossjohn, J. | 登録日 | 2011-06-09 | 公開日 | 2011-10-05 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors Nat.Immunol., 12, 2011
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4YL6
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![BU of 4yl6 by Molmil](/molmil-images/mine/4yl6) | |
6BO0
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![BU of 6bo0 by Molmil](/molmil-images/mine/6bo0) | MdbA protein, a thiol-disulfide oxidoreductase from Corynebacterium matruchotii | 分子名称: | MdbA protein, TETRAETHYLENE GLYCOL | 著者 | Osipiuk, J, Luong, T.Y, Trigar, R, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-11-17 | 公開日 | 2017-12-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural Basis of a Thiol-Disulfide Oxidoreductase in the Hedgehog-Forming Actinobacterium Corynebacterium matruchotii. J. Bacteriol., 200, 2018
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6BHI
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![BU of 6bhi by Molmil](/molmil-images/mine/6bhi) | Crystal structure of SETDB1 with a modified H3 peptide | 分子名称: | Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION | 著者 | Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-10-30 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8, 2017
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6QB8
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![BU of 6qb8 by Molmil](/molmil-images/mine/6qb8) | Human CCT:mLST8 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | 著者 | Cuellar, J, Santiago, C, Ludlam, W.G, Bueno-Carrasco, M.T, Valpuesta, J.M, Willardson, B.M. | 登録日 | 2018-12-20 | 公開日 | 2019-07-03 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly. Nat Commun, 10, 2019
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4KAH
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![BU of 4kah by Molmil](/molmil-images/mine/4kah) | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole | 分子名称: | 4-bromo-1H-pyrazole, ADENOSINE, BROMIDE ION, ... | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-04-22 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole To be Published
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4YO0
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![BU of 4yo0 by Molmil](/molmil-images/mine/4yo0) | Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 with bound PA peptide | 分子名称: | 1,2-ETHANEDIOL, Heavy chain of antigen binding fragment, Fab, ... | 著者 | Fujii, Y, Kitago, Y, Arimori, T, Takagi, J. | 登録日 | 2015-03-11 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state J.Cell.Sci., 129, 2016
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6PU5
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![BU of 6pu5 by Molmil](/molmil-images/mine/6pu5) | MicroED structure of proteinase K recorded on CetaD | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Hattne, J, Martynowycz, M.W, Penzcek, P.A, Gonen, T. | 登録日 | 2019-07-17 | 公開日 | 2019-08-28 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.7 Å) | 主引用文献 | MicroED with the Falcon III direct electron detector. Iucrj, 6, 2019
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6PUB
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![BU of 6pub by Molmil](/molmil-images/mine/6pub) | Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae in the Complex with Crystal Violet | 分子名称: | CHLORIDE ION, CRYSTAL VIOLET, Chloramphenicol acetyltransferase, ... | 著者 | Kim, Y, Maltseva, N, Kuhn, M, Stam, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-07-18 | 公開日 | 2019-09-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae in the Complex with Crystal Violet To Be Published
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7VFJ
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![BU of 7vfj by Molmil](/molmil-images/mine/7vfj) | Cytochrome c-type biogenesis protein CcmABCD | 分子名称: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | 著者 | Zhu, J.P, Zhang, K, Li, J, Zheng, W, Gu, M. | 登録日 | 2021-09-13 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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6BGF
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![BU of 6bgf by Molmil](/molmil-images/mine/6bgf) | Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase | 分子名称: | CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... | 著者 | Liu, A, Li, J, Shin, I. | 登録日 | 2017-10-28 | 公開日 | 2017-12-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | 主引用文献 | Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase. Nat.Chem.Biol., 14, 2018
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6PUR
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![BU of 6pur by Molmil](/molmil-images/mine/6pur) | Human TRPM2 bound to ADPR | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Transient receptor potential cation channel subfamily M member 2 | 著者 | Du, J, Lu, W, Huang, Y. | 登録日 | 2019-07-18 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel. Elife, 8, 2019
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6BHD
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![BU of 6bhd by Molmil](/molmil-images/mine/6bhd) | Crystal structure of SETDB1 with a modified H3 peptide | 分子名称: | Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SODIUM ION, ... | 著者 | Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-10-30 | 公開日 | 2017-12-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8, 2017
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7VFP
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![BU of 7vfp by Molmil](/molmil-images/mine/7vfp) | Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with heme and single ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-09-13 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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6C62
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![BU of 6c62 by Molmil](/molmil-images/mine/6c62) | An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme. | 分子名称: | AtzG, Biuret hydrolase, MAGNESIUM ION | 著者 | Peat, T.S, Esquirol, L, Wilding, M, Liu, J.W, French, N.G, Hartley, C.J, Hideki, O, Easton, C.J, Newman, J, Scott, C. | 登録日 | 2018-01-17 | 公開日 | 2018-03-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | An unexpected vestigial protein complex reveals the evolutionary origins of ans-triazine catabolic enzyme. J. Biol. Chem., 293, 2018
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6C6G
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![BU of 6c6g by Molmil](/molmil-images/mine/6c6g) | An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme. Inhibitor bound complex. | 分子名称: | AtzG, Biuret hydrolase, CALCIUM ION | 著者 | Peat, T.S, Esquirol, L, Wilding, M, Liu, J.W, French, N.G, Hartley, C.J, Hideki, O, Easton, C.J, Newman, J, Scott, C. | 登録日 | 2018-01-18 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An unexpected vestigial protein complex reveals the evolutionary origins of ans-triazine catabolic enzyme. J. Biol. Chem., 293, 2018
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4YUF
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![BU of 4yuf by Molmil](/molmil-images/mine/4yuf) | |
5JIM
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![BU of 5jim by Molmil](/molmil-images/mine/5jim) | Crystal Structure of Human Transthyretin in Complex with Perfluoroktansulfonsyra (PFOS) | 分子名称: | SODIUM ION, Transthyretin, heptadecafluoro-1-octanesulfonic acid | 著者 | Begum, A, Zhang, J, Olofsson, A, Andersson, P, Sauer-Eriksson, A.E. | 登録日 | 2016-04-22 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ. Sci. Technol., 50, 2016
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4YUO
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![BU of 4yuo by Molmil](/molmil-images/mine/4yuo) | High-resolution multiconformer synchrotron model of CypA at 273 K | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | 著者 | Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S. | 登録日 | 2015-03-18 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography. Elife, 4, 2015
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6Q1R
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![BU of 6q1r by Molmil](/molmil-images/mine/6q1r) | |