5OPZ
 
 | | Crystal structure of Serratia marcescens L-Ala D-Glu endopeptidase ChiX | | 分子名称: | CHLORIDE ION, ChiX, ZINC ION | | 著者 | Owen, R.A, Fyfe, P.K, Lodge, A, Biboy, J, Vollmer, W, Hunter, W.N, Sargent, F. | | 登録日 | 2017-08-10 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Structure and activity of ChiX: a peptidoglycan hydrolase required for chitinase secretion by Serratia marcescens.
Biochem. J., 475, 2018
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6FUG
 | | Complement factor D in complex with the inhibitor 3-((3-((3-(aminomethyl)phenyl)amino)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)phenol | | 分子名称: | 3-[[3-[[3-(aminomethyl)phenyl]amino]-1~{H}-pyrazolo[3,4-d]pyrimidin-4-yl]amino]phenol, Complement factor D | | 著者 | Mac Sweeney, A, Ostermann, N, Vulpetti, A, Maibaum, J, Erbel, P, Lorthiois, E, Yoon, T, Randl, S, Ruedisser, S. | | 登録日 | 2018-02-27 | | 公開日 | 2018-06-06 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D.
ACS Med Chem Lett, 9, 2018
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3GFU
 | | FaeE-FaeG chaperone-major pilin complex of F4 ac 5/95 fimbriae | | 分子名称: | Chaperone protein faeE, FaeG, SULFATE ION | | 著者 | Van Molle, I, Moonens, K, Garcia-Pino, A, Buts, L, Bouckaert, J, De Greve, H. | | 登録日 | 2009-02-27 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.991 Å) | | 主引用文献 | Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
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3GGJ
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6CP5
 | | Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of oligomycin bound generated from focused refinement. | | 分子名称: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | | 著者 | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | | 登録日 | 2018-03-13 | | 公開日 | 2018-04-11 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.
Science, 360, 2018
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3G1N
 | | Catalytic domain of the human E3 ubiquitin-protein ligase HUWE1 | | 分子名称: | E3 ubiquitin-protein ligase HUWE1, SODIUM ION | | 著者 | Walker, J.R, Qiu, L, Li, Y, Davis, T, Tempel, W, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-01-30 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Hect Domain of Human HUWE1/MULE
To be Published
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1DYW
 | | Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans | | 分子名称: | CYCLOPHILIN 3 | | 著者 | Dornan, J, Page, A.P, Taylor, P, Wu, S.Y, Winter, A.D, Husi, H, Walkinshaw, M.D. | | 登録日 | 2000-02-10 | | 公開日 | 2000-06-22 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis Elegans
J.Biol.Chem., 274, 1999
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3GHY
 | | Crystal structure of a putative ketopantoate reductase from Ralstonia solanacearum MolK2 | | 分子名称: | Ketopantoate reductase protein | | 著者 | Patskovsky, Y, Ramagopal, U.A, Toro, R, Morano, C, Freeman, J, Chang, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-03-04 | | 公開日 | 2009-03-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a putative ketopantoate reductase from Ralstonia solanacearum MolK2
To be Published
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6G7D
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3G56
 | | Structure of the macrolide biosensor protein, MphR(A) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Regulator of macrolide 2'-phosphotransferase I | | 著者 | Zheng, J, Sagar, V, Smolinsky, A, Bourke, C, LaRonde-LeBlanc, N, Cropp, T.A. | | 登録日 | 2009-02-04 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin
J.Mol.Biol., 387, 2009
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3FW2
 | | C-terminal domain of putative thiol-disulfide oxidoreductase from Bacteroides thetaiotaomicron. | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, thiol-disulfide oxidoreductase | | 著者 | Osipiuk, J, Li, H, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-01-16 | | 公開日 | 2009-01-27 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | X-ray crystal structure of C-terminal domain of putative thiol-disulfide oxidoreductase from Bacteroides thetaiotaomicron.
To be Published
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6G0C
 | | Crystal structure of SdeA catalytic core | | 分子名称: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Ubiquitinating/deubiquitinating enzyme SdeA | | 著者 | Kalayil, S, Bhogaraju, S, Basquin, J, Dikic, I. | | 登録日 | 2018-03-17 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
Nature, 557, 2018
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6AZC
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6AZN
 | | Structural and biochemical characterization of a non-canonical biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841 | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Putative amidase | | 著者 | Peat, T.S, Esquirol, L, Newman, J, Scott, C. | | 登録日 | 2017-09-11 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural and biochemical characterization of the biuret hydrolase (BiuH) from the cyanuric acid catabolism pathway of Rhizobium leguminasorum bv. viciae 3841.
PLoS ONE, 13, 2018
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6G2M
 | | Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PAU | | 分子名称: | 1,2-ETHANEDIOL, 5'(3')-deoxyribonucleotidase, mitochondrial, ... | | 著者 | Pachl, P, Rezacova, P, Brynda, J. | | 登録日 | 2018-03-23 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Structure-based optimization of bisphosphonate nucleoside inhibitors of human 5'(3')-deoxyribonucleotidases
Eur.J.Org.Chem., 2018
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6G45
 | | Crystal structure of mavirus major capsid protein | | 分子名称: | GLYCEROL, Putative major capsid protein | | 著者 | Born, D, Reuter, L, Meinhart, A, Reinstein, J. | | 登録日 | 2018-03-26 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Capsid protein structure, self-assembly, and processing reveal morphogenesis of the marine virophage mavirus.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6GEG
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6BFZ
 | | Crystal structure of enolase from E. coli with a mixture of apo form, substrate, and product form | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-PHOSPHOGLYCERIC ACID, Enolase, ... | | 著者 | Erlandsen, H, Wright, D, Krucinska, J. | | 登録日 | 2017-10-27 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
Biochemistry, 58, 2019
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3GIN
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3G0D
 | | Crystal structure of dipeptidyl peptidase IV in complex with a pyrimidinedione inhibitor 2 | | 分子名称: | 2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, Z, Wallace, M.B, Feng, J, Stafford, J.A, Kaldor, S.W, Shi, L, Skene, R.J, Aertgeerts, K, Lee, B, Jennings, A, Xu, R, Kassel, D, Webb, D.R, Gwaltney, S.L. | | 登録日 | 2009-01-27 | | 公開日 | 2010-02-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV.
J.Med.Chem., 54, 2011
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6FLO
 | | Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei at 2.1 Angstrom resolution | | 分子名称: | GLYCEROL, INOSINE, Protein kinase A regulatory subunit | | 著者 | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | | 登録日 | 2018-01-26 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (2.13868666 Å) | | 主引用文献 | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens.
Elife, 12, 2024
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6FM3
 | | Deoxyguanylosuccinate synthase (DgsS) structure with ADP at 1.9 Angstrom resolution | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylosuccinate synthetase, CHLORIDE ION | | 著者 | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | | 登録日 | 2018-01-30 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP0, dGMP, Magnesium at 2.3 Angstrom resolution
To Be Published
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3FR4
 | | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors | | 分子名称: | 9-[2-(trifluoromethyl)benzyl]-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid, Fatty acid-binding protein, adipocyte | | 著者 | Barf, T, Hammer, K, Lehmann, F, Haile, S, Axen, E, Medina, C, Uppenberg, J, Svensson, S, Rondahl, L, Lundb ck, T. | | 登録日 | 2009-01-08 | | 公開日 | 2009-03-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
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3G46
 | | Ligand migration and cavities within scapharca dimeric hemoglobin: wild type with co bound to heme and chloroform bound to the XE4 cavity | | 分子名称: | CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Knapp, J.E, Pahl, R, Cohen, J, Nichols, J.C, Schulten, K, Gibson, Q.H, Srajer, V, Royer Jr, W.E. | | 登録日 | 2009-02-03 | | 公開日 | 2009-12-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (0.91 Å) | | 主引用文献 | Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
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6B57
 | | tudor in complex with ligand | | 分子名称: | Tudor and KH domain-containing protein, UNKNOWN ATOM OR ION | | 著者 | Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2017-09-28 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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