1FP4
| CRYSTAL STRUCTURE OF THE ALPHA-H195Q MUTANT OF NITROGENASE | 分子名称: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE-MO-S CLUSTER, ... | 著者 | Sorlie, M, Christiansen, J, Lemon, B.J, Peters, J.W, Dean, D.R, Hales, B.J. | 登録日 | 2000-08-30 | 公開日 | 2002-11-20 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanistic features and structure of the nitrogenase alpha-Gln195 MoFe protein Biochemistry, 40, 2001
|
|
2X55
| Yersinia Pestis Plasminogen Activator Pla (Native) | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COAGULASE/FIBRINOLYSIN, SULFATE ION | 著者 | Eren, E, Murphy, M, Goguen, J, van den Berg, B. | 登録日 | 2010-02-05 | 公開日 | 2010-07-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis Structure, 18, 2010
|
|
2WMD
| Crystal structure of NmrA-like family domain containing protein 1 in complex with NADP and 2-(4-chloro-phenylamino)-nicotinic acid | 分子名称: | 2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1 | 著者 | Bhatia, C, Pilka, E, Niesen, F, Yue, W.W, Ugochukwu, E, Savitsky, P, Hozjan, V, Roos, A.K, Filippakopoulos, P, von Delft, F, Heightman, T, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | 登録日 | 2009-06-30 | 公開日 | 2009-07-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Nmra-Like Family Domain Containing Protein 1 To be Published
|
|
5MWG
| Crystal structure of the human BRPF1 bromodomain in complex with BZ091 | 分子名称: | NITRATE ION, Peregrin, ~{N}-[1,4-dimethyl-2,3-bis(oxidanylidene)-7-piperidin-1-yl-quinoxalin-6-yl]-5,6,7,8-tetrahydronaphthalene-2-sulfonamide | 著者 | Zhu, J, Caflisch, A. | 登録日 | 2017-01-18 | 公開日 | 2018-02-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-based discovery of selective BRPF1 bromodomain inhibitors. Eur J Med Chem, 155, 2018
|
|
5QI3
| PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000475a | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 14, ... | 著者 | Schuller, M, Talon, R, Krojer, T, Brandao-Neto, J, Douangamath, A, Zhang, R, von Delft, F, Schuler, H, Kessler, B, Knapp, S, Bountra, C, Arrowsmith, C.H, Edwards, A, Elkins, J. | 登録日 | 2018-05-21 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
|
|
5MWT
| Galectin-1 in Complex with Ligand JB97 | 分子名称: | BETA-MERCAPTOETHANOL, Galectin-1, SULFATE ION, ... | 著者 | Grimm, C, Bechold, J. | 登録日 | 2017-01-19 | 公開日 | 2018-02-14 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (1.711 Å) | 主引用文献 | Structural insights into the redesign of a sucrose phosphorylase by induced loop repositioning To Be Published
|
|
2WYX
| Neutron structure of a class A Beta-lactamase Toho-1 E166A R274N R276N triple mutant | 分子名称: | BETA-LACTAMSE TOHO-1 | 著者 | Tomanicek, S.J, Blakeley, M.P, Cooper, J, Chen, Y, Afonine, P, Coates, L. | 登録日 | 2009-11-20 | 公開日 | 2010-01-12 | 最終更新日 | 2024-05-08 | 実験手法 | NEUTRON DIFFRACTION (2.1 Å) | 主引用文献 | Neutron Diffraction Studies of a Class a Beta-Lactamase Toho-1 E166A R274N R276N Triple Mutant J.Mol.Biol., 396, 2010
|
|
2X5N
| Crystal Structure of the SpRpn10 VWA domain | 分子名称: | 26S PROTEASOME REGULATORY SUBUNIT RPN10, SULFATE ION | 著者 | Riedinger, C, Boehringer, J, Trempe, J.-F, Lowe, E.D, Brown, N.R, Gehring, K, Noble, M.E.M, Gordon, C, Endicott, J.A. | 登録日 | 2010-02-10 | 公開日 | 2010-08-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The Structure of Rpn10 and its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12. J.Biol.Chem., 285, 2010
|
|
6JQ0
| CryoEM structure of Abo1 Walker B (E372Q) mutant hexamer - ATP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Uncharacterized AAA domain-containing protein C31G5.19, ... | 著者 | Cho, C, Jang, J, Song, J.J. | 登録日 | 2019-03-28 | 公開日 | 2019-12-25 | 最終更新日 | 2020-01-01 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone. Nat Commun, 10, 2019
|
|
2WRF
| structure of H2 avian jena hemagglutinin with human receptor | 分子名称: | HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | 登録日 | 2009-09-01 | 公開日 | 2009-09-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
6JQD
| The structural basis of the beta-carbonic anhydrase CafC (L25G and L78G mutant) of the filamentous fungus Aspergillus fumigatus | 分子名称: | Carbonic anhydrase, ZINC ION | 著者 | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | 登録日 | 2019-03-30 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
|
|
5MHE
| |
1FE6
| |
5QI5
| PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000633a | 分子名称: | 2-cyano-~{N}-(1,3,5-trimethylpyrazol-4-yl)ethanamide, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Schuller, M, Talon, R, Krojer, T, Brandao-Neto, J, Douangamath, A, Zhang, R, von Delft, F, Schuler, H, Kessler, B, Knapp, S, Bountra, C, Arrowsmith, C.H, Edwards, A, Elkins, J. | 登録日 | 2018-05-21 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
|
|
2WWT
| Intracellular subtilisin precursor from B. clausii | 分子名称: | INTRACELLULAR SUBTILISIN PROTEASE, SODIUM ION | 著者 | Vevodova, J, Gamble, M, Ariza, A, Dodson, E, Jones, D.D, Wilson, K.S. | 登録日 | 2009-10-27 | 公開日 | 2010-09-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Crystal Structure of an Intracellular Subtilisin Reveals Novel Structural Features Unique to This Subtilisin Family. Structure, 18, 2010
|
|
5MUM
| Glycoside Hydrolase BACINT_00347 | 分子名称: | 1,2-ETHANEDIOL, BACINT_00347, PENTAETHYLENE GLYCOL | 著者 | Munoz-Munoz, J, Cartmell, A, Terrapon, N, Henrissat, B, Gilbert, H.J. | 登録日 | 2017-01-13 | 公開日 | 2017-04-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Unusual active site location and catalytic apparatus in a glycoside hydrolase family. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
2WII
| Complement C3b in complex with factor H domains 1-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ... | 著者 | Wu, J, Janssen, B.J.C, Gros, P. | 登録日 | 2009-05-12 | 公開日 | 2009-06-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat. Immunol., 10, 2009
|
|
2X78
| Human foamy virus integrase - catalytic core. | 分子名称: | INTEGRASE | 著者 | Rety, S, Delelis, O, Rezabkova, L, Dubanchet, B, Legrand, P, Silhan, J, Lewit-Bentley, A. | 登録日 | 2010-02-24 | 公開日 | 2010-08-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase Acta Crystallogr.,Sect.F, 66, 2010
|
|
2WWB
| CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME | 分子名称: | 25S RRNA, 5.8S RRNA, 60S RIBOSOMAL PROTEIN L17-A, ... | 著者 | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | 登録日 | 2009-10-22 | 公開日 | 2009-12-08 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (6.48 Å) | 主引用文献 | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
|
|
2WR5
| structure of influenza H2 duck Ontario hemagglutinin | 分子名称: | HEMAGGLUTININ | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | 登録日 | 2009-08-29 | 公開日 | 2009-09-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2X2Z
| Crystal structure AMA1 from Toxoplasma gondii | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APICAL MEMBRANE ANTIGEN 1, PUTATIVE, ... | 著者 | Crawford, J, Tonkin, M.L, Grujic, O, Boulanger, M.J. | 登録日 | 2010-01-18 | 公開日 | 2010-03-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Characterization of Apical Membrane Antigen 1 (Ama1) from Toxoplasma Gondii. J.Biol.Chem., 285, 2010
|
|
5M5Z
| Chaetomium thermophilum beta-1-3-glucanase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-1,3-glucanase, ... | 著者 | Papageorgiou, A.C, Chen, J, Li, D. | 登録日 | 2016-10-23 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Crystal structure and biological implications of a glycoside hydrolase family 55 beta-1,3-glucanase from Chaetomium thermophilum. Biochim. Biophys. Acta, 1865, 2017
|
|
2WMN
| |
2XA4
| Inhibitors of Jak2 Kinase domain | 分子名称: | 5-CHLORO-N2-[(1S)-1-(5-FLUOROPYRIMIDIN-2-YL)ETHYL]-N4-(5-METHYL-1H-PYRAZOL-3-YL)PYRIMIDINE-2,4-DIAMINE, TYROSINE-PROTEIN KINASE JAK2 | 著者 | Read, J, Green, I, Pollard, H, Howard, T, Mott, R. | 登録日 | 2010-03-26 | 公開日 | 2010-12-15 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Discovery of 5-Chloro-N2-[(1S)-1-(5-Fluoropyrimidin-2-Yl) Ethyl]-N4-(5-Methyl-1H-Pyrazol-3-Yl)Pyrimidine-2,4-Diamine (Azd1480) as a Novel Inhibitor of the Jak/Stat Pathway J.Med.Chem., 54, 2011
|
|
5MI0
| A thermally stabilised version of Plasmodium falciparum RH5 | 分子名称: | MONOCLONAL ANTIBODY 9AD4, Reticulocyte binding-like protein 5,Reticulocyte binding protein 5 | 著者 | Campeotto, I, Goldenzweig, A, Davey, J, Barfod, L, Marshall, J.M, Silk, S.E, Wright, K.E, Draper, S.J, Higgins, M.K, Fleishman, S.J. | 登録日 | 2016-11-27 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|