2WYX

Neutron structure of a class A Beta-lactamase Toho-1 E166A R274N R276N triple mutant

Summary for 2WYX

Entry DOI	10.2210/pdb2wyx/pdb
Related	1BZA 1IYO 1IYP 1IYQ 1IYS 1WE4
Descriptor	BETA-LACTAMSE TOHO-1 (2 entities in total)
Functional Keywords	toho-1, hydrolase, beta-lactamase, ctx- m-type esbls, neutron structure, antibiotic resistance, extended-spectrum beta-lactamases (esbls)
Biological source	ESCHERICHIA COLI
Total number of polymer chains	1
Total formula weight	27503.12
Authors	Tomanicek, S.J.,Blakeley, M.P.,Cooper, J.,Chen, Y.,Afonine, P.,Coates, L. (deposition date: 2009-11-20, release date: 2010-01-12, Last modification date: 2018-05-09)
Primary citation	Tomanicek, S.J.,Blakeley, M.P.,Cooper, J.,Chen, Y.,Afonine, P.,Coates, L. Neutron Diffraction Studies of a Class a Beta-Lactamase Toho-1 E166A R274N R276N Triple Mutant J.Mol.Biol., 396:1070-, 2010 Cited by PubMed: 20036259 DOI: 10.1016/J.JMB.2009.12.036 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION (2.1 Å)

Structure validation