5G4E
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![BU of 5g4e by Molmil](/molmil-images/mine/5g4e) | S. enterica HisA mutant D10G, Dup13-15, Q24L, G102A, V106L | Descriptor: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, ACETIC ACID, GLYCEROL, ... | Authors: | Soderholm, A, Guo, X, Newton, M, Nasvall, J, Duarte, F, Andersson, D, Patrick, W, Selmer, M. | Deposit date: | 2016-05-12 | Release date: | 2017-04-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1YVX
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![BU of 1yvx by Molmil](/molmil-images/mine/1yvx) | Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor | Descriptor: | 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | Deposit date: | 2005-02-16 | Release date: | 2005-03-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
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5G4J
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![BU of 5g4j by Molmil](/molmil-images/mine/5g4j) | Phospholyase A1RDF1 from Arthrobacter in complex with phosphoethanolamine | Descriptor: | PUTATIVE AMINOTRANSFERASE CLASS III PROTEIN, SODIUM ION, {5-hydroxy-6-methyl-4-[(E)-{[2-(phosphonooxy)ethyl]imino}methyl]pyridin-3-yl}methyl dihydrogen phosphate | Authors: | Cuetos, A, Tuan, A.N, Mangas Sanchez, J, Grogan, G. | Deposit date: | 2016-05-13 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue. Chembiochem, 17, 2016
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1ZP7
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![BU of 1zp7 by Molmil](/molmil-images/mine/1zp7) | The structure of Bacillus subtilis RecU Holliday junction resolvase and its role in substrate selection and sequence specific cleavage. | Descriptor: | Recombination protein U | Authors: | McGregor, N, Ayora, S, Sedelnikova, S, Carrasco, B, Alonso, J.C, Thaw, P, Rafferty, J. | Deposit date: | 2005-05-16 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Structure of Bacillus subtilis RecU Holliday Junction Resolvase and Its Role in Substrate Selection and Sequence-Specific Cleavage. Structure, 13, 2005
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3U2Y
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![BU of 3u2y by Molmil](/molmil-images/mine/3u2y) | ATP synthase c10 ring in proton-unlocked conformation at pH 6.1 | Descriptor: | ATP synthase subunit C, mitochondrial | Authors: | Symersky, J, Pagadala, V, Osowski, D, Krah, A, Meier, T, Faraldo-Gomez, J, Mueller, D.M. | Deposit date: | 2011-10-04 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the c(10) ring of the yeast mitochondrial ATP synthase in the open conformation. Nat.Struct.Mol.Biol., 19, 2012
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4R9O
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![BU of 4r9o by Molmil](/molmil-images/mine/4r9o) | Crystal Structure of Putative Aldo/Keto Reductase from Salmonella enterica | Descriptor: | Putative aldo/keto reductase | Authors: | Kim, Y, Maltseva, N, Stam, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-09-05 | Release date: | 2014-09-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Crystal Structure of Putative Aldo/Keto Reductase from Salmonella enterica To be Published
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8J6K
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![BU of 8j6k by Molmil](/molmil-images/mine/8j6k) | Crystal structure of pro-interleukin-18 and caspase-4 complex | Descriptor: | Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ... | Authors: | Sun, Q, Hou, Y.J, Ding, J. | Deposit date: | 2023-04-26 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome. Nature, 624, 2023
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4QRD
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![BU of 4qrd by Molmil](/molmil-images/mine/4qrd) | Structure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine | Descriptor: | MAGNESIUM ION, Methionyl-tRNA synthetase, N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine | Authors: | Li, X, Hilgers, M.T, Stidham, M, Brown-Driver, V, Shaw, K.J, Finn, J. | Deposit date: | 2014-06-30 | Release date: | 2015-07-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Discovery and SAR of a Novel Series of Pyrimidine Antibacterials Targeting Methionyl-tRNA Synthetase to be published
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5GRL
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1YZE
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![BU of 1yze by Molmil](/molmil-images/mine/1yze) | Crystal structure of the N-terminal domain of USP7/HAUSP. | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Saridakis, V, Sheng, Y, Sarkari, F, Holowaty, M.N, Shire, K, Nguyen, T, Zhang, R.G, Liao, J, Lee, W, Edwards, A.M, Arrowsmith, C.H, Frappier, L. | Deposit date: | 2005-02-28 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol.Cell, 18, 2005
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3NF1
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![BU of 3nf1 by Molmil](/molmil-images/mine/3nf1) | Crystal structure of the TPR domain of kinesin light chain 1 | Descriptor: | Kinesin light chain 1 | Authors: | Tong, Y, Tempel, W, Shen, L, Shen, Y, Nedyalkova, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-06-09 | Release date: | 2011-05-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the TPR domain of kinesin light chain 1 to be published
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5WLZ
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![BU of 5wlz by Molmil](/molmil-images/mine/5wlz) | Crystal Structure of Amino Acids 1677-1758 of Human Beta Cardiac Myosin Fused to Xrcc4 | Descriptor: | DNA repair protein XRCC4,Myosin-7 | Authors: | Andreas, M.P, Ajay, G, Gellings, J, Rayment, I. | Deposit date: | 2017-07-28 | Release date: | 2017-08-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Design considerations in coiled-coil fusion constructs for the structural determination of a problematic region of the human cardiac myosin rod. J. Struct. Biol., 200, 2017
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5GJ7
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![BU of 5gj7 by Molmil](/molmil-images/mine/5gj7) | putative Acyl-CoA dehydrogenase | Descriptor: | Acyl-CoA dehydrogenase type 2 domain protein | Authors: | Moon, H, Choe, J. | Deposit date: | 2016-06-28 | Release date: | 2017-07-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Putative Acyl CoA dehydrogenase To Be Published
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8JLV
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![BU of 8jlv by Molmil](/molmil-images/mine/8jlv) | |
5G3M
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![BU of 5g3m by Molmil](/molmil-images/mine/5g3m) | Discovery of a novel secreted phospholipase A2 (sPLA2) inhibitor. | Descriptor: | 4-BENZYLBENZAMIDE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sandmark, J, Bodin, C, Hallberg, K. | Deposit date: | 2016-04-29 | Release date: | 2016-09-14 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Discovery of Azd2716: A Novel Secreted Phospholipase A2 (Spla2) Inhibitor for the Treatment of Coronary Artery Disease Acs Med.Chem.Lett., 7, 2016
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1YGJ
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![BU of 1ygj by Molmil](/molmil-images/mine/1ygj) | Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives | Descriptor: | (2R)-2-({6-[BENZYL(METHYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)BUTAN-1-OL, Pyridoxal kinase | Authors: | Tang, L, Li, M.-H, Cao, P, Wang, F, Chang, W.-R, Bach, S, Reinhardt, J, Ferandin, Y, Koken, M, Galons, H, Wan, Y, Gray, N, Meijer, L, Jiang, T, Liang, D.-C. | Deposit date: | 2005-01-05 | Release date: | 2005-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives J.Biol.Chem., 280, 2005
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5GM9
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![BU of 5gm9 by Molmil](/molmil-images/mine/5gm9) | Crystal structure of a glycoside hydrolase in complex with cellobiose | Descriptor: | Glycoside hydrolase family 45 protein, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Gao, J, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T. | Deposit date: | 2016-07-13 | Release date: | 2017-04-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris Enzyme Microb. Technol., 99, 2017
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1YHY
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![BU of 1yhy by Molmil](/molmil-images/mine/1yhy) | Crystal structure of Arabidopsis thaliana Acetohydroxyacid synthase In Complex With A Sulfonylurea Herbicide, Metsulfuron methyl | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ETHYL DIHYDROGEN DIPHOSPHATE, ... | Authors: | McCourt, J.A, Pang, S.S, King-Scott, J, Guddat, L.W, Duggleby, R.G. | Deposit date: | 2005-01-10 | Release date: | 2006-01-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase Proc.Natl.Acad.Sci.Usa, 103, 2006
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3TQJ
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![BU of 3tqj by Molmil](/molmil-images/mine/3tqj) | Structure of the superoxide dismutase (Fe) (sodB) from Coxiella burnetii | Descriptor: | FE (II) ION, Superoxide dismutase [Fe] | Authors: | Franklin, M.C, Cheung, J, Cassidy, M, Love, J. | Deposit date: | 2011-09-09 | Release date: | 2011-09-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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5GN8
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![BU of 5gn8 by Molmil](/molmil-images/mine/5gn8) | Structure of a 48-mer protein nanocage fabricated from its 24-mer analogue by subunit interface redesign | Descriptor: | CALCIUM ION, Ferritin heavy chain | Authors: | Zhang, S, Zang, J, Zhao, G, Mikami, B. | Deposit date: | 2016-07-19 | Release date: | 2016-12-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | "Silent" Amino Acid Residues at Key Subunit Interfaces Regulate the Geometry of Protein Nanocages ACS Nano, 10, 2016
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8K4X
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![BU of 8k4x by Molmil](/molmil-images/mine/8k4x) | Structure of a triple-helix region of human Collagen type XVII from Trautec | Descriptor: | triple-helix region of human Collagen type XVII | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | Deposit date: | 2023-07-20 | Release date: | 2023-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a triple-helix region of human Collagen type XVII from Trautec. To Be Published
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5GND
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![BU of 5gnd by Molmil](/molmil-images/mine/5gnd) | Structure of Deg protease HhoA from Synechocystis sp. PCC 6803 | Descriptor: | Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ... | Authors: | Dong, W, Wang, J, Liu, L. | Deposit date: | 2016-07-20 | Release date: | 2016-09-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803 Febs Lett., 590, 2016
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4R0Y
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8K4W
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![BU of 8k4w by Molmil](/molmil-images/mine/8k4w) | Structure of a triple-helix region of human collagen type I from Trautec | Descriptor: | CHLORIDE ION, triple-helix region of human collagen type I | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | Deposit date: | 2023-07-20 | Release date: | 2023-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a triple-helix region of human collagen type I from Trautec. To Be Published
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5GAS
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![BU of 5gas by Molmil](/molmil-images/mine/5gas) | Thermus thermophilus V/A-ATPase, conformation 2 | Descriptor: | Archaeal/vacuolar-type H+-ATPase subunit I, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | Authors: | Schep, D.G, Zhao, J, Rubinstein, J.L. | Deposit date: | 2016-02-05 | Release date: | 2016-03-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance. Proc.Natl.Acad.Sci.USA, 113, 2016
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