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8JLV

Beneficial flip of substrate orientation enable determine substrate specificity for zearalenone lactone hydrolase

Summary for 8JLV
Entry DOI10.2210/pdb8jlv/pdb
DescriptorAB hydrolase-1 domain-containing protein (1 entity in total)
Functional Keywordsmycotoxin, zearalenone hydrolase, hydrolase
Biological sourceExophiala aquamarina CBS 119918
Total number of polymer chains6
Total formula weight175885.25
Authors
Xiang, L.,Wang, M.,Zhang, G.,Zhou, J. (deposition date: 2023-06-02, release date: 2023-12-06, Last modification date: 2024-06-19)
Primary citationWang, M.,Zhang, F.,Xiang, L.,Li, M.,Lu, Z.,Wu, P.,Sheng, X.,Zhou, J.,Zhang, G.
Enhancing the activity of zearalenone lactone hydrolase toward the more toxic alpha-zearalanol via a single-point mutation.
Appl.Environ.Microbiol., 90:e0181823-e0181823, 2024
Cited by
PubMed: 38332488
DOI: 10.1128/aem.01818-23
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.99863596858 Å)
Structure validation

224004

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