7AZ7
 
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 37 bound | | Descriptor: | Beta sliding clamp, FORMIC ACID, PENTAETHYLENE GLYCOL, ... | | Authors: | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | Deposit date: | 2020-11-16 | | Release date: | 2021-12-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
|
|
7AZ6
 | | DNA polymerase sliding clamp from Escherichia coli with peptide 36 bound | | Descriptor: | ACETATE ION, Beta sliding clamp, CHLORIDE ION, ... | | Authors: | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | | Deposit date: | 2020-11-16 | | Release date: | 2021-12-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.
J.Med.Chem., 64, 2021
|
|
8P0T
 | |
8P1Y
 | |
7T6E
 | |
7T90
 | | Cryo-EM structure of ACh-bound M2R-Go signaling complex in S2 state | | Descriptor: | ACETYLCHOLINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | Deposit date: | 2021-12-17 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
|
|
6V19
 | | immune receptor complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 72,74cit69-81, GLYCEROL, ... | | Authors: | Lim, J.J, Rossjohn, J. | | Deposit date: | 2019-11-20 | | Release date: | 2020-11-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
|
|
7EKA
 | | crystal structure of epigallocatechin binding with alpha-lactalbumin | | Descriptor: | 2-(3,4,5-TRIHYDROXY-PHENYL)-CHROMAN-3,5,7-TRIOL, Alpha-lactalbumin | | Authors: | Ma, J, Yao, Q, Chen, X, Zang, J. | | Deposit date: | 2021-04-05 | | Release date: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Weak Binding of Epigallocatechin to alpha-Lactalbumin Greatly Improves Its Stability and Uptake by Caco-2 Cells.
J.Agric.Food Chem., 69, 2021
|
|
7T8X
 | | Cryo-EM structure of ACh-bound M2R-Go signaling complex in S1 state | | Descriptor: | ACETYLCHOLINE, Antibody fragment, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | Deposit date: | 2021-12-17 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
|
|
8P8M
 | | Yeast 60S ribosomal subunit, RPL39 deletion | | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. | | Deposit date: | 2023-06-01 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.66 Å) | | Cite: | Yeast 60S ribosomal subunit, RPL39 deletion
To Be Published
|
|
7T96
 | | Cryo-EM structure of S2 state ACh-bound M2R-Go signaling complex with a PAM | | Descriptor: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, ACETYLCHOLINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | Deposit date: | 2021-12-18 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
|
|
3JBP
 | | Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to E-tRNA | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... | | Authors: | Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. | | Deposit date: | 2015-09-16 | | Release date: | 2015-10-14 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.7 Å) | | Cite: | Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
|
|
6VFR
 | | Crystal structure of human protocadherin 18 EC1-EC4 | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Harrison, O.J, Brasch, J, Shapiro, L. | | Deposit date: | 2020-01-06 | | Release date: | 2020-03-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
|
|
1GB9
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | Descriptor: | LYSOZYME, SODIUM ION | | Authors: | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | Deposit date: | 2000-06-26 | | Release date: | 2000-07-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
|
|
7T94
 | | Cryo-EM structure of S1 state ACh-bound M2R-Go signaling complex with a PAM | | Descriptor: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, ACETYLCHOLINE, Antibody fragment, ... | | Authors: | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | Deposit date: | 2021-12-17 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
|
|
6VH2
 | | 2.26 A resolution structure of MERS 3CL protease in complex with inhibitor 7i | | Descriptor: | 4,4-difluorocyclohexyl [(2S)-3-cyclohexyl-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-1-oxopropan-2-yl]carbamate, Orf1a protein | | Authors: | Lovell, S, Battaile, K.P, Kashipathy, M.M, Rathnayake, A.D, Zheng, J, Kim, Y, Nguyen, H.N, Chang, K.O, Groutas, W.C. | | Deposit date: | 2020-01-09 | | Release date: | 2020-08-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice.
Sci Transl Med, 12, 2020
|
|
8P8U
 | | Yeast 60S ribosomal subunit | | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M. | | Deposit date: | 2023-06-02 | | Release date: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.23 Å) | | Cite: | Yeast 60S ribosomal subunit
To Be Published
|
|
7B1W
 | | Crystal structure of plastidial ribulose epimerase RPE1 from the model alga Chlamydomonas reinhardtii | | Descriptor: | Ribulose-phosphate 3-epimerase, ZINC ION | | Authors: | Henri, J, Zaffagnini, M, Tedesco, D, Crozet, P, Lemaire, S.D. | | Deposit date: | 2020-11-25 | | Release date: | 2021-12-08 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.935 Å) | | Cite: | Characterization of chloroplast ribulose-5-phosphate-3-epimerase from the microalga Chlamydomonas reinhardtii.
Plant Physiol., 2023
|
|
7FII
 | | luteinizing hormone/choriogonadotropin receptor-chorionic gonadotropin-Gs complex | | Descriptor: | Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, Glycoprotein hormones alpha chain, ... | | Authors: | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | Deposit date: | 2021-07-31 | | Release date: | 2021-09-29 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
|
|
7B2O
 | |
7FIG
 | | luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid antibody VHH fragment Nb35, Choriogonadotropin subunit beta 3, ... | | Authors: | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | | Deposit date: | 2021-07-31 | | Release date: | 2021-09-29 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structures of full-length glycoprotein hormone receptor signalling complexes.
Nature, 598, 2021
|
|
6V7Z
 | | Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D22 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | | Authors: | Shahine, A, Rossjohn, J. | | Deposit date: | 2019-12-10 | | Release date: | 2020-09-16 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response.
Nat Cancer, 2020
|
|
7B2N
 | | Crystal structure of Chlamydomonas reinhardtii chloroplastic Fructose bisphosphate aldolase | | Descriptor: | CHLORIDE ION, Fructose-bisphosphate aldolase 1, chloroplastic, ... | | Authors: | Le Moigne, T, Lemaire, S.D, Henri, J. | | Deposit date: | 2020-11-27 | | Release date: | 2021-12-08 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Crystal structure of chloroplast fructose-1,6-bisphosphate aldolase from the green alga Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2022
|
|
8P5O
 | | Proline activating adenylation domain of gramicidin S synthetase 2 - GrsB1-Acore | | Descriptor: | Gramicidin S synthase 2 | | Authors: | Stephan, P, Basquin, J, Caputi, L, O'Connor, S.E, Kries, H. | | Deposit date: | 2023-05-24 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Directed Evolution of Piperazic Acid Incorporation by a Nonribosomal Peptide Synthetase.
Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
7TA8
 | | NMR structure of crosslinked cyclophilin A | | Descriptor: | Peptidyl-prolyl cis-trans isomerase A | | Authors: | Lu, M, Toptygin, D, Xiang, Y, Shi, Y, Schwieters, C.D, Lipinski, E.C, Ahn, J, Byeon, I.-J.L, Gronenborn, A.M. | | Deposit date: | 2021-12-20 | | Release date: | 2022-06-01 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink.
J.Am.Chem.Soc., 144, 2022
|
|
