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PDB: 356 件

4GHL
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Structural Basis for Marburg virus VP35 mediate immune evasion mechanisms
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ...
著者Ramanan, P, Borek, D.M, Otwinowski, Z, Leung, D.W, Amarasinghe, G.K.
登録日2012-08-07
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
1AOY
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BU of 1aoy by Molmil
N-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR NMR, 23 STRUCTURES
分子名称: ARGININE REPRESSOR
著者Sunnerhagen, M, Nilges, M, Otting, G.
登録日1997-07-14
公開日1997-09-17
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA-binding domain and model for the complex of multifunctional hexameric arginine repressor with DNA.
Nat.Struct.Biol., 4, 1997
3GRX
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BU of 3grx by Molmil
NMR STRUCTURE OF ESCHERICHIA COLI GLUTAREDOXIN 3-GLUTATHIONE MIXED DISULFIDE COMPLEX, 20 STRUCTURES
分子名称: GLUTAREDOXIN 3, GLUTATHIONE
著者Nordstrand, K, Aslund, F, Holmgren, A, Otting, G, Berndt, K.D.
登録日1998-08-17
公開日1999-03-30
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献NMR structure of Escherichia coli glutaredoxin 3-glutathione mixed disulfide complex: implications for the enzymatic mechanism.
J.Mol.Biol., 286, 1999
1ZFO
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BU of 1zfo by Molmil
AMINO-TERMINAL LIM-DOMAIN PEPTIDE OF LASP-1, NMR
分子名称: LASP-1, ZINC ION
著者Hammarstrom, A, Berndt, K.D, Sillard, R, Adermann, K, Otting, G.
登録日1996-05-06
公開日1996-11-08
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of a naturally-occurring zinc-peptide complex demonstrates that the N-terminal zinc-binding module of the Lasp-1 LIM domain is an independent folding unit.
Biochemistry, 35, 1996
2ARR
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BU of 2arr by Molmil
Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagmggvmtgr-oh
分子名称: 14-mer from Plasminogen activator inhibitor-2, Plasminogen activator inhibitor-2
著者Di Giusto, D.A, Sutherland, A.P, Jankova, L, Harrop, S.J, Curmi, P.M, King, G.C.
登録日2005-08-21
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities
J.Mol.Biol., 353, 2005
1HP3
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BU of 1hp3 by Molmil
C-TERMINAL TRUNCATION OF OMEGA-ATRACOTOXIN-HV2A (CT-HV2A)
分子名称: OMEGA-ATRACOTOXIN-HV2A
著者Wang, X.-H, King, G.F.
登録日2000-12-12
公開日2002-12-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Discovery and structure of a potent and highly specific blocker of insect calcium channels
J.Biol.Chem., 276, 2001
3Q5U
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BU of 3q5u by Molmil
A minimal NLS from human scramblase 4 complexed with importin alpha
分子名称: Importin subunit alpha-2, Phospholipid scramblase 4
著者Bhardwaj, A, Cingolani, G.
登録日2010-12-29
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin {alpha}1.
J.Biol.Chem., 286, 2011
1CCD
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BU of 1ccd by Molmil
REFINED STRUCTURE OF RAT CLARA CELL 17 KDA PROTEIN AT 3.0 ANGSTROMS RESOLUTION
分子名称: CLARA CELL 17 kD PROTEIN, SULFATE ION
著者Umland, T.C, Swaminathan, S, Furey, W, Singh, G, Pletcher, J, Sax, M.
登録日1991-09-17
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Refined structure of rat Clara cell 17 kDa protein at 3.0 A resolution.
J.Mol.Biol., 224, 1992
4PP7
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BU of 4pp7 by Molmil
Highly Potent and Selective 3-N-methylquinazoline-4(3H)-one Based Inhibitors of B-RafV600E Kinase
分子名称: N-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide, Serine/threonine-protein kinase B-raf
著者Wenglowsky, S, Ren, L, Grina, J, Hansen, J.D, Laird, E.R, Moreno, D, Dinkel, V, Gloor, S.L, Hastings, G, Rana, S, Rasor, K, Sturgis, H.L, Voegtli, W.C, Vigers, G.P.A, Willis, B, Mathieu, S, Rudolph, J.
登録日2014-02-26
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.
Bioorg.Med.Chem.Lett., 24, 2014
1AXJ
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BU of 1axj by Molmil
FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F), NMR, 20 STRUCTURES
分子名称: FLAVIN MONONUCLEOTIDE, FMN-BINDING PROTEIN
著者Liepinsh, E, Otting, G.
登録日1997-10-16
公開日1998-01-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Pathway of chymotrypsin evolution suggested by the structure of the FMN-binding protein from Desulfovibrio vulgaris (Miyazaki F)
Nat.Struct.Biol., 4, 1997
3FYR
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BU of 3fyr by Molmil
Crystal structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis
分子名称: Sporulation inhibitor sda
著者Jacques, D.A, Streamer, M, King, G.F, Guss, J.M, Trewhella, J, Langley, D.B.
登録日2009-01-23
公開日2009-06-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis and insights into its solution state
Acta Crystallogr.,Sect.D, 65, 2009
1MSZ
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BU of 1msz by Molmil
Solution structure of the R3H domain from human Smubp-2
分子名称: DNA-binding protein SMUBP-2
著者Liepinsh, E, Leonchiks, A, Sharipo, A, Guignard, L, Otting, G.
登録日2002-09-20
公開日2002-10-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the R3H domain from human Smubp-2
J.Mol.Biol., 326, 2003
2YBA
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BU of 2yba by Molmil
Crystal structure of Nurf55 in complex with histone H3
分子名称: HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
2YB8
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Crystal structure of Nurf55 in complex with Su(z)12
分子名称: POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
7YLA
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BU of 7yla by Molmil
Cryo-EM structure of 50S-HflX complex
分子名称: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Damu, W, Ning, G.
登録日2022-07-25
公開日2023-01-04
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Cryo-EM Structure of the 50S-HflX Complex Reveals a Novel Mechanism of Antibiotic Resistance in E. coli
Biorxiv, 2022
4EI2
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BU of 4ei2 by Molmil
Crystal Structures of MthK RCK gating ring bound to Barium
分子名称: BARIUM ION, Calcium-gated potassium channel mthK
著者Smith, F.J, Cingolani, G, Rothberg, B.S.
登録日2012-04-04
公開日2012-12-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.108 Å)
主引用文献Crystal Structure of a Ba(2+)-Bound Gating Ring Reveals Elementary Steps in RCK Domain Activation.
Structure, 20, 2012
1HVW
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BU of 1hvw by Molmil
HAIRPINLESS MUTANT OF OMEGA-ATRACOTOXIN-HV1A
分子名称: OMEGA-ATRACOTOXIN-HV1A
著者Fletcher, J.I, King, G.F.
登録日2001-01-08
公開日2001-01-17
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Functional significance of the beta hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a.
J.Biol.Chem., 276, 2001
7YQK
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BU of 7yqk by Molmil
cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1
分子名称: DNA (145-MER), Histone H2AX, Histone H2B, ...
著者Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L.
登録日2022-08-07
公開日2022-08-17
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes.
J.Am.Chem.Soc., 144, 2022
3UBY
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BU of 3uby by Molmil
Crystal structure of human alklyadenine DNA glycosylase in a lower and higher-affinity complex with DNA
分子名称: DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDC)P*TP*TP*GP*CP*CP*T)-3'), DNA-3-methyladenine glycosylase
著者Setser, J.W, Lingaraju, G.M, Davis, C.A, Samson, L.D, Drennan, C.L.
登録日2011-10-25
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase.
Biochemistry, 51, 2012
5TBK
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BU of 5tbk by Molmil
Crystal structure of human importin a3 bound to RCC1
分子名称: Importin subunit alpha-3, Regulator of chromosome condensation
著者Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
登録日2016-09-12
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
2AYA
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BU of 2aya by Molmil
Solution Structure of the C-Terminal 14 kDa Domain of the tau subunit from Escherichia coli DNA Polymerase III
分子名称: DNA polymerase III subunit tau
著者Jergic, S, Dixon, N.E, Otting, G, Su, X.C.
登録日2005-09-07
公開日2006-11-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit.
Nucleic Acids Res., 35, 2007
3DA7
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BU of 3da7 by Molmil
A conformationally strained, circular permutant of barnase
分子名称: Barnase circular permutant, Barstar
著者Mitrousis, G, Butler, J, Loh, S.N, Cingolani, G.
登録日2008-05-28
公開日2009-04-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and thermodynamic analysis of a conformationally strained circular permutant of barnase.
Biochemistry, 48, 2009
1WNJ
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BU of 1wnj by Molmil
NMR structure of human coactosin-like protein
分子名称: Coactosin-like protein
著者Liepinsh, E, Rakonjac, M, Boissonneault, V, Provost, P, Samuelsson, B, Radmark, O, Otting, G.
登録日2004-08-05
公開日2004-08-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure of human coactosin-like protein
J.Biomol.Nmr, 30, 2004
3TJ3
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BU of 3tj3 by Molmil
Structure of importin a5 bound to the N-terminus of Nup50
分子名称: Importin subunit alpha-1, Nuclear pore complex protein Nup50
著者Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G.
登録日2011-08-23
公開日2011-11-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5.
J.Biol.Chem., 287, 2012
1FOV
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GLUTAREDOXIN 3 FROM ESCHERICHIA COLI IN THE FULLY OXIDIZED FORM
分子名称: GLUTAREDOXIN 3
著者Nordstrand, K, Sandstrom, A, Aslund, F, Holmgren, A, Otting, G, Berndt, K.D.
登録日2000-08-29
公開日2000-10-26
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR structure of oxidized glutaredoxin 3 from Escherichia coli.
J.Mol.Biol., 303, 2000

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