3W4I
| Crystal Structure of human DAAO in complex with coumpound 8 | Descriptor: | D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, pyridine-2,3-diol | Authors: | Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M. | Deposit date: | 2013-01-09 | Release date: | 2013-05-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | 4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors. J.Med.Chem., 56, 2013
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1GD2
| CRYSTAL STRUCTURE OF BZIP TRANSCRIPTION FACTOR PAP1 BOUND TO DNA | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*TP*AP*CP*GP*TP*AP*AP*CP*C)-3'), TRANSCRIPTION FACTOR PAP1 | Authors: | Fujii, Y, Shimizu, T, Toda, T, Yanagida, M, Hakoshima, T. | Deposit date: | 2000-08-25 | Release date: | 2000-10-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the diversity of DNA recognition by bZIP transcription factors. Nat.Struct.Biol., 7, 2000
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4DVZ
| Crystal structure of the Helicobacter pylori CagA oncoprotein | Descriptor: | Cytotoxicity-associated immunodominant antigen | Authors: | Hayashi, T, Senda, M, Morohashi, H, Higashi, H, Horio, M, Kashiba, Y, Nagase, L, Sasaya, D, Shimizu, T, Venugopalan, N, Kumeta, H, Noda, N, Inagaki, F, Senda, T, Hatakeyama, M. | Deposit date: | 2012-02-23 | Release date: | 2012-07-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA Cell Host Microbe, 12, 2012
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3W4J
| Crystal Structure of human DAAO in complex with coumpound 12 | Descriptor: | 3-hydroxy-5-(2-phenylethyl)pyridin-2(1H)-one, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M. | Deposit date: | 2013-01-09 | Release date: | 2013-05-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | 4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors. J.Med.Chem., 56, 2013
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1UJB
| Structure of the protein histidine phosphatase SixA | Descriptor: | CALCIUM ION, Phosphohistidine phosphatase sixA | Authors: | Hamada, K, Kato, M, Shimizu, T, Ihara, K, Mizuno, T, Hakoshima, T. | Deposit date: | 2003-07-31 | Release date: | 2005-01-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay. Genes Cells, 10, 2005
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1UJC
| Structure of the protein histidine phosphatase SixA complexed with tungstate | Descriptor: | CALCIUM ION, Phosphohistidine phosphatase sixA, TUNGSTATE(VI)ION | Authors: | Hamada, K, Kato, M, Shimizu, T, Ihara, K, Mizuno, T, Hakoshima, T. | Deposit date: | 2003-07-31 | Release date: | 2005-01-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay. Genes Cells, 10, 2005
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1V3V
| Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2 | Descriptor: | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Hori, T, Yokomizo, T, Ago, H, Sugahara, M, Ueno, G, Yamamoto, M, Kumasaka, T, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-11-06 | Release date: | 2004-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem., 279, 2004
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1GC6
| CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN | Authors: | Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. | Deposit date: | 2000-07-21 | Release date: | 2000-09-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
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1GC7
| CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN | Descriptor: | RADIXIN | Authors: | Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. | Deposit date: | 2000-07-21 | Release date: | 2000-09-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
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1V3T
| Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase | Authors: | Hori, T, Yokomizo, T, Ago, H, Sugahara, M, Ueno, G, Yamamoto, M, Kumasaka, T, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-11-05 | Release date: | 2004-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem., 279, 2004
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1V3U
| Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase in apo form | Descriptor: | CHLORIDE ION, leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase | Authors: | Hori, T, Yokomizo, T, Ago, H, Sugahara, M, Ueno, G, Yamamoto, M, Kumasaka, T, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-11-05 | Release date: | 2004-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem., 279, 2004
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3VKX
| Structure of PCNA | Descriptor: | 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... | Authors: | Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. | Deposit date: | 2011-11-26 | Release date: | 2012-03-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication J.Biol.Chem., 287, 2012
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1GLN
| ARCHITECTURES OF CLASS-DEFINING AND SPECIFIC DOMAINS OF GLUTAMYL-TRNA SYNTHETASE | Descriptor: | GLUTAMYL-TRNA SYNTHETASE | Authors: | Nureki, O, Vassylyev, D.G, Katayanagi, K, Shimizu, T, Sekine, S, Kigawa, T, Miyazawa, T, Yokoyama, S, Morikawa, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1994-07-20 | Release date: | 1995-10-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Architectures of class-defining and specific domains of glutamyl-tRNA synthetase. Science, 267, 1995
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1UF4
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase | Descriptor: | N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-23 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid To be published
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1UF7
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-valine | Descriptor: | 3-METHYL-2-UREIDO-BUTYRIC ACID, N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-26 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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1UF5
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine | Descriptor: | 1,2-ETHANEDIOL, 4-METHYLSULFANYL-2-UREIDO-BUTYRIC ACID, N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-23 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of C171A/V236A mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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2OFF
| The crystal structure of Glycogen Phosphorylase b in complex with a potent allosteric inhibitor | Descriptor: | 2-DEOXY-3,4-BIS-O-[3-(4-HYDROXYPHENYL)PROPANOYL]-L-THREO-PENTARIC ACID, Glycogen phosphorylase, muscle form | Authors: | Tiraidis, C, Alexacou, K.-M, Zographos, S.E, Leonidas, D.D, Gimisis, T, Oikonomakos, N.G. | Deposit date: | 2007-01-03 | Release date: | 2007-08-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | FR258900, a potential anti-hyperglycemic drug, binds at the allosteric site of glycogen phosphorylase Protein Sci., 16, 2007
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1UF8
| Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Phenylalanine | Descriptor: | D-[(AMINO)CARBONYL]PHENYLALANINE, N-carbamyl-D-amino acid amidohydrolase | Authors: | Hashimoto, H, Aoki, M, Shimizu, T, Nakai, T, Morikawa, H, Ikenaka, Y, Takahashi, S, Sato, M. | Deposit date: | 2003-05-26 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase To be published
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2E1N
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2CT9
| The crystal structure of calcineurin B homologous proein 1 (CHP1) | Descriptor: | CALCIUM ION, Calcium-binding protein p22 | Authors: | Naoe, Y, Arita, K, Hashimoto, H, Kanazawa, H, Sato, M, Shimizu, T. | Deposit date: | 2005-05-23 | Release date: | 2005-07-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural characterization of calcineurin B homologous protein 1 J.Biol.Chem., 280, 2005
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2DEX
| Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal peptide including Arg17 | Descriptor: | 10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ... | Authors: | Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. | Deposit date: | 2006-02-18 | Release date: | 2006-04-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
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2DEW
| Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal tail including Arg8 | Descriptor: | 10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ... | Authors: | Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. | Deposit date: | 2006-02-18 | Release date: | 2006-04-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
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2DEY
| Crystal structure of human peptidylarginine deiminase 4 in complex with histone H4 N-terminal tail including Arg3 | Descriptor: | 10-mer peptide from histone H4, CALCIUM ION, Protein-arginine deiminase type IV, ... | Authors: | Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. | Deposit date: | 2006-02-18 | Release date: | 2006-04-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006
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1UHN
| The crystal structure of the calcium binding protein AtCBL2 from Arabidopsis thaliana | Descriptor: | CALCIUM ION, calcineurin B-like protein 2 | Authors: | Nagae, M, Nozawa, A, Koizumi, N, Sano, H, Hashimoto, H, Sato, M, Shimizu, T. | Deposit date: | 2003-07-07 | Release date: | 2003-11-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of the Novel Calcium-binding Protein AtCBL2 from Arabidopsis thaliana J.Biol.Chem., 278, 2003
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1V9Y
| Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form) | Descriptor: | Heme pas sensor protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kurokawa, H, Lee, D.S, Watanabe, M, Sagami, I, Mikami, B, Raman, C.S, Shimizu, T. | Deposit date: | 2004-02-04 | Release date: | 2004-05-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | A redox-controlled molecular switch revealed by the crystal structure of a bacterial heme PAS sensor. J.Biol.Chem., 279, 2004
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