2KUN
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![BU of 2kun by Molmil](/molmil-images/mine/2kun) | Three dimensional structure of HuPrP(90-231 M129 Q212P) | Descriptor: | Major prion protein | Authors: | Ilc, G, Giachin, G, Jaremko, M, Jaremko, L, Zhukov, I, Plavec, J, Legname, G, Benetti, F. | Deposit date: | 2010-02-23 | Release date: | 2010-08-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features. Plos One, 5, 2010
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2MVK
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![BU of 2mvk by Molmil](/molmil-images/mine/2mvk) | Solution structure of phosphorylated cytosolic part of Trop2 | Descriptor: | Tumor-associated calcium signal transducer 2 | Authors: | Ilc, G, Plavec, J, Vidmar, T, Pavsic, M, Lenarcic, B. | Deposit date: | 2014-10-08 | Release date: | 2015-05-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The cytosolic tail of the tumor marker protein Trop2--a structural switch triggered by phosphorylation. Sci Rep, 5, 2015
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2MVL
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![BU of 2mvl by Molmil](/molmil-images/mine/2mvl) | Solution structure of cytosolic part of Trop2 | Descriptor: | Tumor-associated calcium signal transducer 2 | Authors: | Ilc, G, Plavec, J, Vidmar, T, Pavsic, M, Lenarcic, B. | Deposit date: | 2014-10-08 | Release date: | 2015-05-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The cytosolic tail of the tumor marker protein Trop2--a structural switch triggered by phosphorylation. Sci Rep, 5, 2015
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2LEJ
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![BU of 2lej by Molmil](/molmil-images/mine/2lej) | human prion protein mutant HuPrP(90-231, M129, V210I) | Descriptor: | Major prion protein | Authors: | Biljan, I, Ilc, G, Giachin, G, Raspadori, A, Zhukov, I, Plavec, J, Legname, G. | Deposit date: | 2011-06-16 | Release date: | 2011-08-17 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Toward the Molecular Basis of Inherited Prion Diseases: NMR Structure of the Human Prion Protein with V210I Mutation. J.Mol.Biol., 412, 2011
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6FNV
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![BU of 6fnv by Molmil](/molmil-images/mine/6fnv) | |
5LKN
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![BU of 5lkn by Molmil](/molmil-images/mine/5lkn) | NMR solution structure of human FNIII domain 2 of NCAM | Descriptor: | Neural cell adhesion molecule 1 | Authors: | Slapsak, U, Salzano, G, Amin, L, Abskharon, R.N.N, Ilc, G, Zupancic, B, Biljan, I, Plavec, J, Giachin, G, Legname, G. | Deposit date: | 2016-07-22 | Release date: | 2016-09-14 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain. J.Biol.Chem., 291, 2016
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5L6R
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![BU of 5l6r by Molmil](/molmil-images/mine/5l6r) | PrP226* - Solution-state NMR structure of truncated human prion protein | Descriptor: | Major prion protein | Authors: | Kovac, V, Zupancic, B, Ilc, G, Curin Serbec, V, Plavec, J. | Deposit date: | 2016-05-31 | Release date: | 2016-10-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Truncated prion protein PrP226* - A structural view on its role in amyloid disease. Biochem. Biophys. Res. Commun., 484, 2017
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2LFT
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![BU of 2lft by Molmil](/molmil-images/mine/2lft) | Human prion protein with E219K protective polymorphism | Descriptor: | Major prion protein | Authors: | Biljan, I, Ilc, G, Giacin, G, Zhukov, I, Plavec, J, Legname, G. | Deposit date: | 2011-07-14 | Release date: | 2012-06-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism. Biochem.J., 446, 2012
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2LSB
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![BU of 2lsb by Molmil](/molmil-images/mine/2lsb) | Solution-state NMR structure of the human prion protein | Descriptor: | Major prion protein | Authors: | Biljan, I, Ilc, G, Giancin, G, Zhukov, I, Plavec, J, Legname, G. | Deposit date: | 2012-04-26 | Release date: | 2012-06-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism. Biochem.J., 446, 2012
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2LV1
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![BU of 2lv1 by Molmil](/molmil-images/mine/2lv1) | Solution-state NMR structure of prion protein mutant V210I at neutral pH | Descriptor: | Major prion protein | Authors: | Biljan, I, Ilc, G, Giachin, G, Legname, G, Plavec, J. | Deposit date: | 2012-06-26 | Release date: | 2012-09-19 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Rearrangements at Physiological pH: Nuclear Magnetic Resonance Insights from the V210I Human Prion Protein Mutant. Biochemistry, 51, 2012
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2MAE
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![BU of 2mae by Molmil](/molmil-images/mine/2mae) | |
2N8Z
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![BU of 2n8z by Molmil](/molmil-images/mine/2n8z) | Apo form of Calmodulin-Like Domain of Human Non-Muscle alpha-actinin 1 | Descriptor: | Alpha-actinin-1 | Authors: | Drmota Prebil, S, Slapsak, U, de Almeida Ribeiro, E, Pavsic, M, Ilc, G, Zielinska, K, Hartl, M, Backman, L, Plavec, J, Lenarcic, B, Djinovic-Carugo, K. | Deposit date: | 2015-10-28 | Release date: | 2016-06-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and calcium-binding studies of calmodulin-like domain of human non-muscle alpha-actinin-1. Sci Rep, 6, 2016
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2N8Y
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![BU of 2n8y by Molmil](/molmil-images/mine/2n8y) | Holo form of Calmodulin-Like Domain of Human Non-Muscle alpha-actinin 1 | Descriptor: | Alpha-actinin-1, CALCIUM ION | Authors: | Drmota Prebil, S, Slapsak, U, de Almeida Ribeiro, E, Pavsic, M, Ilc, G, Zielinska, K, Hartl, M, Backman, L, Plavec, J, Lenarcic, B, Djinovic-Carugo, K. | Deposit date: | 2015-10-28 | Release date: | 2016-06-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and calcium-binding studies of calmodulin-like domain of human non-muscle alpha-actinin-1. Sci Rep, 6, 2016
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5EEQ
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![BU of 5eeq by Molmil](/molmil-images/mine/5eeq) | Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor | Descriptor: | Bicyclic Peptide Inhibitor, Growth factor receptor-bound protein 7, PHOSPHATE ION | Authors: | Ambaye, N.D, Watson, G.M, Wilce, M.C.J, Wilce, G.M. | Deposit date: | 2015-10-23 | Release date: | 2016-06-15 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7. Sci Rep, 6, 2016
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1HE7
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![BU of 1he7 by Molmil](/molmil-images/mine/1he7) | Human Nerve growth factor receptor TrkA | Descriptor: | GLYCEROL, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR | Authors: | Banfield, M, Robertson, A, Allen, S, Dando, J, Tyler, S, Bennett, G, Brain, S, Mason, G, Holden, P, Clarke, A, Naylor, R, Wilcock, G, Brady, R, Dawbarn, D. | Deposit date: | 2000-11-20 | Release date: | 2001-04-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification and Structure of the Nerve Growth Factor Binding Site on Trka. Biochem.Biophys.Res.Commun., 282, 2001
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1XS7
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![BU of 1xs7 by Molmil](/molmil-images/mine/1xs7) | Crystal Structure of a cycloamide-urethane-derived novel inhibitor bound to human brain memapsin 2 (beta-secretase). | Descriptor: | Beta-secretase 1, N-[(4S,5S,7R)-8-({(S)-1-[(BENZYLAMINO)OXOMETHYL]-2-METHYLPROPYL}AMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXO-OCT-4-YL]-(4S,7S)-4 -ISOPROPYL-2,5,9-TRIOXO-1-OXA-3,6,10-TRIAZACYCLOHEXADECANE-7-CARBOXAMIDE | Authors: | Ghosh, A, Devasamudram, T, Hong, L, DeZutter, C, Xu, X, Weerasena, V, Koelsch, G, Bilcer, G, Tang, J. | Deposit date: | 2004-10-18 | Release date: | 2004-12-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase). Bioorg.Med.Chem.Lett., 15, 2005
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