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PDB: 168 件

5DC9
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CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL B
分子名称: AS25 monobody, GLYCEROL, IMIDAZOLE, ...
著者Wojcik, J.B, Koide, A, Koide, S.
登録日2015-08-23
公開日2016-03-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
5CWU
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Crystal structure of Chaetomium thermophilum Nup188 TAIL domain
分子名称: GLYCEROL, Nucleoporin NUP188
著者Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A.
登録日2015-07-28
公開日2015-09-16
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5CWV
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Crystal structure of Chaetomium thermophilum Nup192 TAIL domain
分子名称: Nucleoporin NUP192
著者Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A.
登録日2015-07-28
公開日2015-09-16
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (3.155 Å)
主引用文献Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5CWW
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Crystal structure of the Chaetomium thermophilum heterotrimeric Nup82 NTD-Nup159 TAIL-Nup145N APD complex
分子名称: Nucleoporin NUP145N, Nucleoporin NUP159, Nucleoporin NUP82
著者Stuwe, T, Bley, C.J, Thierbach, K, Petrovic, S, Schilbach, S, Mayo, D.J, Perriches, T, Rundlet, E.J, Jeon, Y.E, Collins, L.N, Lin, D.H, Paduch, M, Koide, A, Lu, V, Fischer, J, Hurt, E, Koide, S, Kossiakoff, A.A, Hoelz, A.
登録日2015-07-28
公開日2015-09-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5DC4
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CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL A
分子名称: AS25 monobody, GLYCEROL, Tyrosine-protein kinase ABL1
著者Wojcik, J.B, Koide, A, Koide, S.
登録日2015-08-23
公開日2016-03-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
5FN0
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Crystal structure of Pseudomonas fluorescens kynurenine-3- monooxygenase (KMO) in complex with GSK180
分子名称: 3-(5,6-DICHLORO-2-OXOBENZO[D]OXAZOL-3(2H)-YL)PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, KYNURENINE 3-MONOOXYGENASE
著者Mole, D.J, Webster, S.P, Uings, I, Zheng, X, Binnie, M, Wilson, K, Hutchinson, J.P, Mirguet, O, Walker, A, Beaufils, B, Ancellin, N, Trottet, L, Beneton, V, Mowat, C.G, Wilkinson, M, Rowland, P, Haslam, C, McBride, A, Homer, N.Z.M, Baily, J.E, Sharp, M.G.F, Garden, O.J, Hughes, J, Howie, S.E.M, Holmes, D, Liddle, J, Iredale, J.P.
登録日2015-11-10
公開日2016-01-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Kynurenine-3-Monooxygenase Inhibition Prevents Multiple Organ Failure in Rodent Models of Acute Pancreatitis.
Nat.Med. (N.Y.), 22, 2016
5E95
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Crystal Structure of Mb(NS1)/H-Ras Complex
分子名称: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Eguchi, R.R, Sha, F, Gupta, A, Koide, A, Koide, S.
登録日2015-10-14
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Inhibition of RAS function through targeting an allosteric regulatory site.
Nat. Chem. Biol., 13, 2017
4JQI
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Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide
分子名称: 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ...
著者Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J.
登録日2013-03-20
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013
4ZG8
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Crystal structure of Endoglucanase from Perinereis brevicirris
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Fewings, R.S, Swiderska, A, Sanchez-Weatherby, J, Sorensen, T.L.-M, Schnorr, K.M, Kneale, G.G, McGeehan, J.E.
登録日2015-04-22
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Biophysical and structural characterisation of the endoglucanase from Perinereis brevicirris
To Be Published
5V7P
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Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase), in complex with a monobody
分子名称: DECANE, Protein-S-isoprenylcysteine O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Long, S.B, Diver, M.M, Pedi, L, Koide, A, Koide, S.
登録日2017-03-20
公開日2018-01-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.
Nature, 553, 2018
2AF5
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2.5A X-ray Structure of Engineered OspA protein
分子名称: Engineered Outer Surface Protein A (OspA) with the inserted two beta-hairpins
著者Makabe, K, Mcelheny, D, Tereshko, V, Hilyard, A, Koide, A, Koide, S.
登録日2005-07-25
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3CH8
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The crystal structure of PDZ-Fibronectin fusion protein
分子名称: C-terminal octapeptide from protein ARVCF, MAGNESIUM ION, fusion protein PDZ-Fibronectin,Fibronectin
著者Makabe, K, Huang, J, Koide, A, Koide, S.
登録日2008-03-08
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution.
J.Mol.Biol., 392, 2009
5VG9
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Structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase) without a monobody
分子名称: Protein-S-isoprenylcysteine O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Long, S.B, Diver, M.M, Pedi, L, Koide, A, Koide, S.
登録日2017-04-10
公開日2018-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.
Nature, 553, 2018
3EC5
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BU of 3ec5 by Molmil
The crystal structure of Thioflavin-T (ThT) binding OspA mutant
分子名称: Outer Surface Protein A, TETRAETHYLENE GLYCOL
著者Biancalana, M, Makabe, K, Koide, A, Koide, S.
登録日2008-08-28
公開日2009-02-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies
J.Mol.Biol., 385, 2009
2OY8
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The crystal structure of OspA mutant
分子名称: Outer surface protein A
著者Makabe, K, Terechko, V, Koide, A, Koide, S.
登録日2007-02-21
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Aromatic cross-strand ladders control the structure and stability of beta-rich peptide self-assembly mimics
J.Mol.Biol., 383, 2008
2OY7
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The crystal structure of OspA mutant
分子名称: Outer surface protein A
著者Makabe, K, Terechko, V, Koide, A, Koide, S.
登録日2007-02-21
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Aromatic cross-strand ladders control the structure and stability of beta-rich peptide self-assembly mimics
J.Mol.Biol., 383, 2008
2P46
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Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: se5b-ortho-2 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.
分子名称: ANTIBODY CAB-RN05, Ribonuclease pancreatic, ZINC ION
著者Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A.
登録日2007-03-11
公開日2008-03-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P42
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Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE3-mono-2 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold
分子名称: ANTIBODY CAB-RN05, MAGNESIUM ION, Ribonuclease pancreatic
著者Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A.
登録日2007-03-11
公開日2008-03-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P48
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Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.3A resolution: SE5B-tetra crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.
分子名称: ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION
著者Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A.
登録日2007-03-11
公開日2008-03-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P45
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Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.1A resolution: SE5B-ORTHO-1 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold.
分子名称: ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION
著者Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A.
登録日2007-03-11
公開日2008-03-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
2P43
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Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.65A resolution: SE3-mono-1 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold
分子名称: ANTIBODY CAB-RN05, Ribonuclease pancreatic
著者Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A.
登録日2007-03-11
公開日2008-03-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
Protein Sci., 17, 2008
1VDS
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BU of 1vds by Molmil
The crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in space
分子名称: Lysozyme C
著者Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, DeLucas, L.J, Hirose, M.
登録日2004-03-24
公開日2004-04-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of the tetragonal form of hen egg white lysozyme at 1.6 angstroms resolution in space
to be published
1VDQ
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The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution
分子名称: Lysozyme C
著者Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, DeLucas, L.J, Hirose, M.
登録日2004-03-24
公開日2004-04-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution
to be published
1VDT
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The crystal structure of the tetragonal form of hen egg white lysozyme at 1.7 angstroms resolution under basic conditions in space
分子名称: Lysozyme C
著者Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, DeLucas, L.J, Hirose, M.
登録日2004-03-24
公開日2004-04-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of the tetragonal form of hen egg white lysozyme at 1.7 angstroms resolution under basic conditions in space
to be published
6RPB
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Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S.
登録日2019-05-14
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
J Immunol., 204, 2020

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