5VG9

Structure of the eukaryotic intramembrane Ras methyltransferase ICMT (isoprenylcysteine carboxyl methyltransferase) without a monobody

Summary for 5VG9

Entry DOI	10.2210/pdb5vg9/pdb
Related	5V7P
Descriptor	Protein-S-isoprenylcysteine O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE (2 entities in total)
Functional Keywords	membrane protein, membrane enzyme, methyltransferase, transferase
Biological source	Tribolium castaneum (Red flour beetle)
Cellular location	Endoplasmic reticulum membrane ; Multi-pass membrane protein : D6WJ77
Total number of polymer chains	1
Total formula weight	33197.56
Authors	Long, S.B.,Diver, M.M.,Pedi, L.,Koide, A.,Koide, S. (deposition date: 2017-04-10, release date: 2018-01-17, Last modification date: 2024-03-13)
Primary citation	Diver, M.M.,Pedi, L.,Koide, A.,Koide, S.,Long, S.B. Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT. Nature, 553:526-529, 2018 Cited by PubMed: 29342140 DOI: 10.1038/nature25439 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4 Å)

Structure validation