8S2U
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8RXA
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8RWU
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8EEC
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6WGI
| Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution | 分子名称: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WGG
| Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | 分子名称: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WGC
| Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | 分子名称: | Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZI3
| Crystal structure of OleP-6DEB bound to L-rhamnose | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, ... | 著者 | Montemiglio, L.C, Savino, C, Vallone, B, Parisi, G, Freda, I. | 登録日 | 2020-06-24 | 公開日 | 2020-10-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate. Biomolecules, 10, 2020
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6ZJH
| Trehalose transferase from Thermoproteus uzoniensis soaked with trehalose | 分子名称: | GLYCEROL, Trehalose phosphorylase/synthase, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | 著者 | Bento, I, Mestrom, L, Marsden, S.R, van der Eijk, H, Laustsen, J.U, Jeffries, C.M, Svergun, D.I, Hagedoorn, P.-H, Hanefeld, U. | 登録日 | 2020-06-29 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Anomeric Selectivity of Trehalose Transferase with Rare l-Sugars. Acs Catalysis, 10, 2020
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6ZJ7
| Trehalose transferase (TreT) from Thermoproteus uzoniensis soaked with Mg | 分子名称: | GLYCEROL, TETRAETHYLENE GLYCOL, THIOCYANATE ION, ... | 著者 | Bento, I, Mestrom, L, Marsden, S.R, van der Eijk, H, Laustsen, J.U, Jeffries, C.M, Svergun, D.I, Hagedoorn, P.-H, Hanefeld, U. | 登録日 | 2020-06-28 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Anomeric Selectivity of Trehalose Transferase with Rare l-Sugars. Acs Catalysis, 10, 2020
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6ZG3
| the structure of ECF PanT transporter in a complex with a nanobody | 分子名称: | CA14381 nanobody, CITRIC ACID, Conserved hypothetical membrane protein, ... | 著者 | Setyawati, I, Guskov, A, Slotboom, D.J. | 登録日 | 2020-06-18 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters. Elife, 9, 2020
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6ZBV
| Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor and sybody Sb_GlyT1#7 | 分子名称: | Sodium- and chloride-dependent glycine transporter 1,Sodium- and chloride-dependent glycine transporter 1, Sybody Sb_GlyT1#7, [5-fluoranyl-6-(oxan-4-yloxy)-1,3-dihydroisoindol-2-yl]-[5-methylsulfonyl-2-[2,2,3,3,3-pentakis(fluoranyl)propoxy]phenyl]methanone | 著者 | Shahsavar, A, Stohler, P, Bourenkov, G, Zimmermann, I, Siegrist, M, Guba, W, Pinard, E, Sinning, S, Seeger, M.A, Schneider, T.R, Dawson, R.J.P, Nissen, P. | 登録日 | 2020-06-09 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural insights into the inhibition of glycine reuptake. Nature, 591, 2021
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6ZL1
| Crystal structure of human serum albumin in complex with the MCL-1 neutralizing Alphabody CMPX-383B | 分子名称: | Albumin, CMPX-383B | 著者 | Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I. | 登録日 | 2020-06-30 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.272 Å) | 主引用文献 | Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting. Sci Adv, 7, 2021
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6ZIE
| Crystal structure of MCL-1 in complex with a neutralizing Alphabody CMPX-383B | 分子名称: | CMPX-383B, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION | 著者 | Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I. | 登録日 | 2020-06-25 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting. Sci Adv, 7, 2021
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6YZF
| Crystal structure of the M295Y variant of Ssl1 | 分子名称: | COPPER (II) ION, Copper oxidase, GLU-HIS-SER, ... | 著者 | Mielenbrink, S, Olbrich, A, Urlacher, V, Span, I. | 登録日 | 2020-05-06 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | 主引用文献 | Effect of the axial ligand mutation on spectral and structural properties of Ssl1 laccase To Be Published
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6YZD
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6ZK7
| Crystal Structure of human PYROXD1/FAD complex | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 | 著者 | Meinhart, A, Asanovic, I, Martinez, J, Clausen, T. | 登録日 | 2020-06-30 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response. Mol.Cell, 81, 2021
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6YZY
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6ZLB
| Thioredoxin glutathione reductase from Schistosoma mansoni in complex with Indole-3-carbinol | 分子名称: | 1~{H}-indol-3-ylmethanol, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Fata, F, Silvestri, I, Williams, D.L, Angelucci, F. | 登録日 | 2020-06-30 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments. Acs Infect Dis., 7, 2021
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6Z26
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6YWW
| MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion | 分子名称: | DNA (5'-D(*AP*TP*AP*TP*AP*AP*TP*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*CP*AP*G)-3'), DNA/RNA (5'-D(*TP*CP*TP*GP*CP*AP*CP*A)-R(P*(5HC))-D(P*AP*CP*AP*CP*AP*AP*TP*TP*AP*TP*A)-3'), Truncated methyl CpG binding protein 2 transcript 1 | 著者 | Ibrahim, A, Papin, C, Mohideen-Abdul, K, Gras, S.L, Stoll, I, Bronner, C, Dimitrov, S, Klaholz, B.P, Hamiche, A. | 登録日 | 2020-04-30 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion. Science, 372, 2021
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6ZQQ
| Structure of the Pmt3-MIR domain with bound ligands | 分子名称: | GLYCEROL, PMT3 isoform 1 | 著者 | Wild, K, Chiapparino, A, Hackmann, Y, Mortensen, S, Sinning, I. | 登録日 | 2020-07-10 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Functional implications of MIR domains in protein O -mannosylation. Elife, 9, 2020
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6ZXF
| Cryo-EM structure of a late human pre-40S ribosomal subunit - State G | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. | 登録日 | 2020-07-29 | 公開日 | 2020-12-02 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
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6PH2
| Complete LOV domain from the LOV-HK sensory protein from Brucella abortus (mutant C69S, construct 15-155) | 分子名称: | Blue-light-activated histidine kinase, FLAVIN MONONUCLEOTIDE | 著者 | Rinaldi, J, Otero, L.H, Fernandez, I, Goldbaum, F.A, Shin, H, Yang, X, Klinke, S. | 登録日 | 2019-06-25 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
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6PH3
| LOV-PAS construct from the LOV-HK sensory protein from Brucella abortus (dark-adapted, construct 15-273) | 分子名称: | Blue-light-activated histidine kinase, FLAVIN MONONUCLEOTIDE | 著者 | Rinaldi, J, Otero, L.H, Fernandez, I, Goldbaum, F.A, Shin, H, Yang, X, Klinke, S. | 登録日 | 2019-06-25 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase. Mbio, 12, 2021
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