8P3Z
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![BU of 8p3z by Molmil](/molmil-images/mine/8p3z) | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2 | Descriptor: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | Authors: | Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H. | Deposit date: | 2023-05-18 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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8P27
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![BU of 8p27 by Molmil](/molmil-images/mine/8p27) | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, dATP-bound state | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | Authors: | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | Deposit date: | 2023-05-15 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Activity modulation in anaerobic ribonucleotide reductases: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site Elife, 2023
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8P3Y
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![BU of 8p3y by Molmil](/molmil-images/mine/8p3y) | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3 | Descriptor: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | Authors: | Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H. | Deposit date: | 2023-05-18 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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8OP2
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![BU of 8op2 by Molmil](/molmil-images/mine/8op2) | |
8P2S
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![BU of 8p2s by Molmil](/molmil-images/mine/8p2s) | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, ATP/dTTP/GTP-bound state | Descriptor: | Anaerobic ribonucleoside-triphosphate reductase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Bimai, O, Banerjee, I, Sjoberg, B.M, Logan, D.T. | Deposit date: | 2023-05-16 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023
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8P2D
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![BU of 8p2d by Molmil](/molmil-images/mine/8p2d) | Cryo-EM structure of the dimeric form of the anaerobic ribonucleotide reductase from Prevotella copri produced in the presence of dATP and CTP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, MAGNESIUM ION | Authors: | Banerjee, I, Bimai, O, Sjoberg, B.M, Logan, D.T. | Deposit date: | 2023-05-15 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site eLife, 2023
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8P39
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![BU of 8p39 by Molmil](/molmil-images/mine/8p39) | Cryo-EM structure of the anaerobic ribonucleotide reductase from Prevotella copri in its dimeric, dGTP/ATP-bound state | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Anaerobic ribonucleoside-triphosphate reductase, ... | Authors: | Bimai, O, Banerjee, I, Sjoberg, B.M, Logan, D.T. | Deposit date: | 2023-05-17 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Activity modulation in anaerobic ribonucleotide reductase: nucleotide binding to the ATP-cone mediates long-range order-disorder transitions in the active site To be published
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8PHJ
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![BU of 8phj by Molmil](/molmil-images/mine/8phj) | cA4-bound Cami1 in complex with 70S ribosome | Descriptor: | 16S rRNA, 23S rRNA (2862-MER), 5S rRNA, ... | Authors: | Tamulaitiene, G, Mogila, I, Sasnauskas, G, Tamulaitis, G. | Deposit date: | 2023-06-20 | Release date: | 2023-12-13 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling. Science, 382, 2023
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8P9V
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![BU of 8p9v by Molmil](/molmil-images/mine/8p9v) | Crystal Structure of Two-Domain Laccase mutant M199G/R240H/D268N from Streptomyces griseoflavus | Descriptor: | COPPER (II) ION, OXYGEN MOLECULE, PEROXIDE ION, ... | Authors: | Kolyadenko, I.A, Tishchenko, S.V, Gabdulkhakov, A.G. | Deposit date: | 2023-06-06 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Insight into the Amino Acid Environment of the Two-Domain Laccase's Trinuclear Copper Cluster. Int J Mol Sci, 24, 2023
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8P9U
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![BU of 8p9u by Molmil](/molmil-images/mine/8p9u) | Crystal Structure of Two-Domain Laccase mutant M199A/D268N from Streptomyces griseoflavus | Descriptor: | CALCIUM ION, COPPER (II) ION, OXYGEN MOLECULE, ... | Authors: | Kolyadenko, I.A, Tishchenko, S.V, Gabdulkhakov, A.G. | Deposit date: | 2023-06-06 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insight into the Amino Acid Environment of the Two-Domain Laccase's Trinuclear Copper Cluster. Int J Mol Sci, 24, 2023
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8P1F
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![BU of 8p1f by Molmil](/molmil-images/mine/8p1f) | X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001909. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-azanyl-1-phenyl-piperidine-4-carboxylic acid, Acetylcholine-binding protein | Authors: | Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. | Deposit date: | 2023-05-12 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
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8P22
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![BU of 8p22 by Molmil](/molmil-images/mine/8p22) | X-ray structure of acetylcholine-binding protein (AChBP) in complex with IOTA376. | Descriptor: | 2-[(2~{R})-1-ethylimidazolidin-2-yl]-6-pyridin-2-yl-pyridine, Acetylcholine-binding protein, GLYCEROL, ... | Authors: | Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. | Deposit date: | 2023-05-14 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
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8P1E
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![BU of 8p1e by Molmil](/molmil-images/mine/8p1e) | X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL001613. | Descriptor: | 1-[4-(trifluoromethyl)pyridin-2-yl]piperazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, ... | Authors: | Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. | Deposit date: | 2023-05-11 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
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8P11
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![BU of 8p11 by Molmil](/molmil-images/mine/8p11) | X-ray structure of acetylcholine-binding protein (AChBP) in complex with FL003044. | Descriptor: | 4-(4-chlorophenyl)piperidin-4-ol, Acetylcholine-binding protein, CHLORIDE ION, ... | Authors: | Cederfelt, D, Boronat, P, Dobritzsch, D, Hennig, S, Fitzgerald, E.A, de Esch, I.J.P, Danielson, U.H. | Deposit date: | 2023-05-11 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Elucidating the regulation of ligand gated ion channels via biophysical studies of ligand-induced conformational dynamics of acetylcholine binding proteins To Be Published
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8P4P
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![BU of 8p4p by Molmil](/molmil-images/mine/8p4p) | Structure average of GroEL14 complexes found in the cytosol of Escherichia coli overexpressing GroEL obtained by cryo electron tomography | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, ... | Authors: | Wagner, J, Caravajal, A.I, Beck, F, Bracher, A, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | Deposit date: | 2023-05-23 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Visualizing chaperonin function in situ by cryo-electron tomography Nature, 2024
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8P4R
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![BU of 8p4r by Molmil](/molmil-images/mine/8p4r) | In situ structure average of GroEL14-GroES14 complexes in Escherichia coli cytosol obtained by cryo electron tomography | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | Authors: | Wagner, J, Caravajal, A.I, Beck, F, Bracher, A, Wan, W, Bohn, S, Koerner, R, Baumeister, W, Fernandez-Busnadiego, R, Hartl, F.U. | Deposit date: | 2023-05-23 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (11.9 Å) | Cite: | Visualizing chaperonin function in situ by cryo-electron tomography Nature, 2024
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7SJ1
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![BU of 7sj1 by Molmil](/molmil-images/mine/7sj1) | Structure of shaker-W434F | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker | Authors: | Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J. | Deposit date: | 2021-10-15 | Release date: | 2022-03-30 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the Shaker Kv channel and mechanism of slow C-type inactivation. Sci Adv, 8, 2022
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7SIP
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![BU of 7sip by Molmil](/molmil-images/mine/7sip) | Structure of shaker-IR | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker | Authors: | Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J. | Deposit date: | 2021-10-14 | Release date: | 2022-03-30 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the Shaker Kv channel and mechanism of slow C-type inactivation. Sci Adv, 8, 2022
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7SAV
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![BU of 7sav by Molmil](/molmil-images/mine/7sav) | Native mu-conotoxin KIIIA isomer | Descriptor: | Mu-conotoxin KIIIA | Authors: | Schroeder, C.I, Tran, H.N.T. | Deposit date: | 2021-09-23 | Release date: | 2022-05-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers. J.Biol.Chem., 298, 2022
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5AP6
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![BU of 5ap6 by Molmil](/molmil-images/mine/5ap6) | Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DUAL SPECIFICITY PROTEIN KINASE TTK, ... | Authors: | Gurden, M.D, Westwood, I.M, Faisal, A, Naud, S, Cheung, K.M, McAndrew, C, Wood, A, Schmitt, J, Boxall, K, Mak, G, Workman, P, Burke, R, Hoelder, S, Blagg, J, van Montfort, R, Linardopoulos, S. | Deposit date: | 2015-09-14 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Naturally Occurring Mutations in the Mps1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res., 75, 2015
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7SHP
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![BU of 7shp by Molmil](/molmil-images/mine/7shp) | Crystal structure of hSTING in complex with c[2',3'-(ribo-2'-G, xylo-3'-A)-MP](RJ244) | Descriptor: | (2S,5R,7R,8R,10S,12aR,14R,15R,15aR,16R)-7-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-2,10,15,16-tetrahydroxyoctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein | Authors: | Xie, W, Lama, L, Yang, X.J, Kuryavyi, V, Nudelman, I, Glickman, J.F, Jones, R.A, Tuschl, T, Patel, D.J. | Deposit date: | 2021-10-11 | Release date: | 2022-10-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists. Cell Chem Biol, 2023
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5AP3
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![BU of 5ap3 by Molmil](/molmil-images/mine/5ap3) | Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. | Descriptor: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 9-CYCLOPENTYL-2-[[2-METHOXY-4-[(1-METHYLPIPERIDIN-4-YL)OXY]-PHENYL]AMINO]-7-METHYL-7,9-DIHYDRO-8H-PURIN-8-ONE, ... | Authors: | Gurden, M.D, Westwood, I.M, Faisal, A, Naud, S, Cheung, K.J, McAndrew, C, Wood, A, Schmitt, J, Boxall, K, Mak, G, Workman, P, Burke, R, Hoelder, S, Blagg, J, van Montfort, R.L.M, Linardopoulos, S. | Deposit date: | 2015-09-14 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Naturally Occurring Mutations in the Mps1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res., 75, 2015
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7RVB
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![BU of 7rvb by Molmil](/molmil-images/mine/7rvb) | High resolution map of molecular chaperone Artemin | Descriptor: | Ferritin | Authors: | Parvate, A.D, Powell, S.M, Brookreason, J.T, Novikova, I.V, Evans, J.E. | Deposit date: | 2021-08-18 | Release date: | 2022-12-14 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.04 Å) | Cite: | Cryo-EM structure of the diapause chaperone artemin. Front Mol Biosci, 9, 2022
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7SAW
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![BU of 7saw by Molmil](/molmil-images/mine/7saw) | Mu-conotoxin KIIIA isomer 2 | Descriptor: | Mu-conotoxin KIIIA | Authors: | Schroeder, C.I, Tran, H.N.T. | Deposit date: | 2021-09-23 | Release date: | 2022-05-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers. J.Biol.Chem., 298, 2022
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5AP7
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![BU of 5ap7 by Molmil](/molmil-images/mine/5ap7) | Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, MONOPOLAR SPINDLE KINASE 1, ... | Authors: | Gurden, M.D, Westwood, I.M, Faisal, A, Naud, S, Cheung, K.M, McAndrew, C, Wood, A, Schmitt, J, Boxall, K, Mak, G, Workman, P, Burke, R, Hoelder, S, Blagg, J, van Montfort, R, Linardopoulos, S. | Deposit date: | 2015-09-14 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Naturally Occurring Mutations in the Mps1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Res., 75, 2015
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