3UON
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![BU of 3uon by Molmil](/molmil-images/mine/3uon) | Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist | 分子名称: | (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, CHLORIDE ION, Human M2 muscarinic acetylcholine, ... | 著者 | Haga, K, Kruse, A.C, Asada, H, Yurugi-Kobayashi, T, Shiroishi, M, Zhang, C, Weis, W.I, Okada, T, Kobilka, B.K, Haga, T, Kobayashi, T. | 登録日 | 2011-11-16 | 公開日 | 2012-02-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist. Nature, 482, 2012
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3R2T
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![BU of 3r2t by Molmil](/molmil-images/mine/3r2t) | 2.2 Angstrom Resolution Crystal Structure of Superantigen-like Protein from Staphylococcus aureus subsp. aureus NCTC 8325. | 分子名称: | Putative uncharacterized protein, SULFATE ION | 著者 | Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Kiryukhina, O, Falugi, F, Bottomley, M, Bagnoli, F, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2011-03-14 | 公開日 | 2011-03-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | 2.2 Angstrom Resolution Crystal Structure of Superantigen-like Protein from Staphylococcus aureus subsp. aureus NCTC 8325. TO BE PUBLISHED
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3UV5
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![BU of 3uv5 by Molmil](/molmil-images/mine/3uv5) | Crystal Structure of the tandem bromodomains of human Transcription initiation factor TFIID subunit 1 (TAF1) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1 | 著者 | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-29 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3UVY
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![BU of 3uvy by Molmil](/molmil-images/mine/3uvy) | Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac) | 分子名称: | Bromodomain-containing protein 4, Histone H4 | 著者 | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-30 | 公開日 | 2012-01-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3R72
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![BU of 3r72 by Molmil](/molmil-images/mine/3r72) | Apis mellifera odorant binding protein 5 | 分子名称: | N-BUTYL-BENZENESULFONAMIDE, Odorant binding protein ASP5 | 著者 | Spinelli, S, Iovinella, I, Lagarde, A, Tegoni, M, Pelosi, P, Cambillau, C. | 登録日 | 2011-03-22 | 公開日 | 2012-04-04 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal structure of Apis mellifera odorant binding protein 5 To be Published
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4A8O
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![BU of 4a8o by Molmil](/molmil-images/mine/4a8o) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | 著者 | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | 登録日 | 2011-11-21 | 公開日 | 2012-07-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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4APP
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![BU of 4app by Molmil](/molmil-images/mine/4app) | Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide | 分子名称: | GLYCEROL, N-[6,6-dimethyl-5-[(2S)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide, SERINE/THREONINE-PROTEIN KINASE PAK 4 | 著者 | Knighton, D.D, Deng, Y.L, Wang, C, Guo, C, McAlpine, I, Zhang, J, Kephart, S, Johnson, M.C, Li, H, Bouzida, D, Yang, A, Dong, L, Marakovits, J, Tikhe, J, Richardson, P, Guo, L.C, Kania, R, Edwards, M.P, Kraynov, E, Christensen, J, Piraino, J, Lee, J, Dagostino, E, Del-Carmen, C, Smeal, T, Murray, B.W. | 登録日 | 2012-04-04 | 公開日 | 2012-06-06 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of Pyrroloaminopyrazoles as Novel Pak Inhibitors. J.Med.Chem., 55, 2012
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3QJB
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4AFD
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![BU of 4afd by Molmil](/molmil-images/mine/4afd) | Structural and biochemical characterization of a novel Carbohydrate Binding Module of endoglucanase Cel5A from Eubacterium cellulosolvens with a partially bound cellotetraose moeity. | 分子名称: | ENDOGLUCANASE CEL5A, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Luis, A.S, Venditto, I, Prates, J.A.M, Ferreira, L.M.A, Gilbert, H.J, Fontes, C.M.G.A, Najmudin, S. | 登録日 | 2012-01-18 | 公開日 | 2012-12-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Understanding How Noncatalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan. J.Biol.Chem., 288, 2013
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3QP0
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![BU of 3qp0 by Molmil](/molmil-images/mine/3qp0) | HIV-1 protease (mutant Q7K L33I L63I) in complex with a novel inhibitor | 分子名称: | (4aS,7aS)-1,4-bis[3-(hydroxymethyl)benzyl]hexahydro-1H-pyrrolo[3,4-b]pyrazine-2,3-dione, CHLORIDE ION, Protease | 著者 | Lindemann, I, Heine, A, Klebe, G. | 登録日 | 2011-02-11 | 公開日 | 2012-02-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Novel inhibitors for HIV-1 protease To be Published
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3Q7C
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![BU of 3q7c by Molmil](/molmil-images/mine/3q7c) | Exonuclease domain of Lassa virus nucleoprotein bound to manganese | 分子名称: | MANGANESE (II) ION, Nucleoprotein, PHOSPHATE ION, ... | 著者 | Hastie, K.M, Kimberlin, C.R, Zandonatti, M.A, MacRae, I.J, Saphire, E.O. | 登録日 | 2011-01-04 | 公開日 | 2011-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression. Proc.Natl.Acad.Sci.USA, 108, 2011
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3UPA
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![BU of 3upa by Molmil](/molmil-images/mine/3upa) | A general strategy for the generation of human antibody variable domains with increased aggregation resistance | 分子名称: | kappa light chain variable domain | 著者 | Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. | 登録日 | 2011-11-17 | 公開日 | 2012-06-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109, 2012
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3UV6
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![BU of 3uv6 by Molmil](/molmil-images/mine/3uv6) | Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301) | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-hydroxybutyl trihydrogen diphosphate, IRON/SULFUR CLUSTER | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-29 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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3U3K
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![BU of 3u3k by Molmil](/molmil-images/mine/3u3k) | Crystal structure of hSULT1A1 bound to PAP and 2-Naphtol | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase 1A1, naphthalen-2-ol | 著者 | Guttman, C, Berger, I, Aharoni, A, Zarivach, R. | 登録日 | 2011-10-06 | 公開日 | 2011-11-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | The molecular basis for the broad substrate specificity of human sulfotransferase 1A1. Plos One, 6, 2011
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3V6A
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3V6Z
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![BU of 3v6z by Molmil](/molmil-images/mine/3v6z) | Crystal Structure of Hepatitis B Virus e-antigen | 分子名称: | Fab e6 Heavy Chain, Fab e6 Light Chain, e-antigen | 著者 | Dimattia, M.A, Watts, N.R, Stahl, S.J, Grimes, J.M, Steven, A.C, Stuart, D.I, Wingfield, P.T. | 登録日 | 2011-12-20 | 公開日 | 2013-02-06 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein. Structure, 21, 2013
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3UR3
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![BU of 3ur3 by Molmil](/molmil-images/mine/3ur3) | Structure of the Cmr2 subunit of the CRISPR RNA silencing complex | 分子名称: | CALCIUM ION, Cmr2dHD, ZINC ION | 著者 | Cocozaki, A.I, Ramia, N.F, Shao, Y, Hale, C.R, Terns, R.M, Terns, M.P, Li, H. | 登録日 | 2011-11-21 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing Complex. Structure, 20, 2012
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3UT2
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![BU of 3ut2 by Molmil](/molmil-images/mine/3ut2) | Crystal Structure of Fungal MagKatG2 | 分子名称: | Catalase-peroxidase 2, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Zamocky, M, Garcia-Fernandez, M.Q, Gasselhuber, B, Jakopitsch, C, Furtmuller, P.G, Loewen, P.C, Fita, I, Obinger, C, Carpena, X. | 登録日 | 2011-11-24 | 公開日 | 2012-07-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.549 Å) | 主引用文献 | High Conformational Stability of Secreted Eukaryotic Catalase-peroxidases: ANSWERS FROM FIRST CRYSTAL STRUCTURE AND UNFOLDING STUDIES. J.Biol.Chem., 287, 2012
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3UVD
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![BU of 3uvd by Molmil](/molmil-images/mine/3uvd) | Crystal Structure of the bromodomain of human Transcription activator BRG1 (SMARCA4) in complex with N-Methyl-2-pyrrolidone | 分子名称: | 1-methylpyrrolidin-2-one, Transcription activator BRG1 | 著者 | Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-29 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3TL0
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![BU of 3tl0 by Molmil](/molmil-images/mine/3tl0) | Structure of SHP2 N-SH2 domain in complex with RLNpYAQLWHR peptide | 分子名称: | RLNpYAQLWHR peptide, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. | 登録日 | 2011-08-29 | 公開日 | 2011-09-28 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50, 2011
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3TMA
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![BU of 3tma by Molmil](/molmil-images/mine/3tma) | Crystal structure of TrmN from Thermus thermophilus | 分子名称: | PHOSPHATE ION, methyltransferase | 著者 | Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W. | 登録日 | 2011-08-31 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life. Nucleic Acids Res., 40, 2012
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4A92
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![BU of 4a92 by Molmil](/molmil-images/mine/4a92) | Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor. | 分子名称: | (1'R,2R,2'S,6S,24AS)-17-FLUORO-6-(1-METHYL-2-OXOPIPERIDINE-3-CARBOXAMIDO)-19,19-DIOXIDO-5,21,24-TRIOXO-2'-VINYL-1,2,3,5,6,7,8,9,10,11,12,13,14,20,21,23,24,24A-OCTADECAHYDROSPIRO[BENZO[S]PYRROLO[2,1-G][1,2,5,8,18]THIATETRAAZACYCLOICOSINE-22,1'-CYCLOPRO-2-CARBOXYLATEPAN]-2-YL 4-FLUOROISOINDOLINE, SERINE PROTEASE NS3, ZINC ION | 著者 | Schiering, N, D'Arcy, A, Simic, O, Eder, J, Raman, P, Svergun, D.I, Bodendorf, U. | 登録日 | 2011-11-23 | 公開日 | 2011-12-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | A Macrocyclic Hcv Ns3/4A Protease Inhibitor Interacts with Protease and Helicase Residues in the Complex with its Full- Length Target. Proc.Natl.Acad.Sci.USA, 108, 2011
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4AB6
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![BU of 4ab6 by Molmil](/molmil-images/mine/4ab6) | Regulatory domain structure of NMB2055 (MetR), C103S C106S mutant, a LysR family regulator from N. meningitidis | 分子名称: | SULFATE ION, TRANSCRIPTIONAL REGULATOR, LYSR FAMILY | 著者 | Sainsbury, S, Ren, J, Saunders, N.J, Stuart, D.I, Owens, R.J. | 登録日 | 2011-12-07 | 公開日 | 2012-07-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the Regulatory Domain of the Lysr Family Regulator Nmb2055 (Metr-Like Protein) from Neisseria Meningitidis Acta Crystallogr.,Sect.F, 68, 2012
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3U2J
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![BU of 3u2j by Molmil](/molmil-images/mine/3u2j) | Neutron crystal structure of human Transthyretin | 分子名称: | Transthyretin | 著者 | Yokoyama, T, Mizuguchi, M, Nabeshima, Y, Kusaka, K, Yamada, T, Hosoya, T, Ohhara, T, Kurihara, K, Tomoyori, K, Tanaka, I, Niimura, N. | 登録日 | 2011-10-03 | 公開日 | 2012-02-22 | 最終更新日 | 2023-11-01 | 実験手法 | NEUTRON DIFFRACTION (2 Å) | 主引用文献 | Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin J.Struct.Biol., 177, 2012
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3U0R
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![BU of 3u0r by Molmil](/molmil-images/mine/3u0r) | Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules | 分子名称: | Apoptosis inhibitor 5 | 著者 | Han, B.G, Kim, K.H, Jeong, K.C, Cho, J.W, Noh, K.H, Kim, T.W, Yoon, H.J, Suh, S.W, Lee, S.H, Lee, B.I. | 登録日 | 2011-09-29 | 公開日 | 2012-02-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules. J.Biol.Chem., 287, 2012
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