4F0F
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![BU of 4f0f by Molmil](/molmil-images/mine/4f0f) | Crystal Structure of the Roco4 Kinase Domain bound to AppCp from D. discoideum | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase roco4 | 著者 | Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A. | 登録日 | 2012-05-04 | 公開日 | 2012-06-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. Proc.Natl.Acad.Sci.USA, 109, 2012
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4NML
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![BU of 4nml by Molmil](/molmil-images/mine/4nml) | 2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from Toxoplasma gondii ME49 in complex with DL-Malic acid | 分子名称: | CHLORIDE ION, D-MALATE, Ribulose 5-phosphate isomerase | 著者 | Halavaty, A.S, Dubrovska, I, Flores, K, Shanmugam, D, Shuvalova, L, Roos, D, Ruan, J, Ngo, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-11-15 | 公開日 | 2013-12-04 | 最終更新日 | 2021-01-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii . Front Cell Infect Microbiol, 8, 2018
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3VH6
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![BU of 3vh6 by Molmil](/molmil-images/mine/3vh6) | Crystal structure of the chicken CENP-T histone fold/CENP-W/CENP-S/CENP-X heterotetrameric complex, crystal form II | 分子名称: | CENP-S, CENP-T, CENP-W, ... | 著者 | Nishino, T, Takeuchi, K, Gascoigne, K.E, Suzuki, A, Hori, T, Oyama, T, Morikawa, K, Cheeseman, I.M, Fukagawa, T. | 登録日 | 2011-08-23 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.351 Å) | 主引用文献 | CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold Cell(Cambridge,Mass.), 148, 2012
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4EYY
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![BU of 4eyy by Molmil](/molmil-images/mine/4eyy) | Crystal Structure of the IcmR-IcmQ complex from Legionella pneumophila | 分子名称: | IcmQ, IcmR | 著者 | Farelli, J.D, Gumbart, J, Akey, I.V, Amyot, W, Hempstead, A.D, Head, J.F, McKnight, C.J, Isberg, R.R, Akey, C.W. | 登録日 | 2012-05-02 | 公開日 | 2013-05-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | IcmQ in the Type 4b secretion system contains an NAD+ binding domain. Structure, 21, 2013
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4MUA
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![BU of 4mua by Molmil](/molmil-images/mine/4mua) | Schistosoma mansoni (Blood Fluke) Sulfotransferase | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, Sulfotransferase | 著者 | Valentim, C.L.L, Cioli, D, Chevalier, F.D, Cao, X, Taylor, A.B, Holloway, S.P, Pica-Mattoccia, L, Guidi, A, Basso, A, Tsai, I.J, Berriman, M, Carvalho-Queiroz, C, Almeida, M, Aguilar, H, Frantz, D.E, Hart, P.J, Anderson, T.J.C, LoVerde, P.T. | 登録日 | 2013-09-21 | 公開日 | 2013-12-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites. Science, 342, 2013
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5W6L
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![BU of 5w6l by Molmil](/molmil-images/mine/5w6l) | Crystal Structure of RRSP, a MARTX Toxin Effector Domain from Vibrio vulnificus CMCP6 | 分子名称: | CHLORIDE ION, GLYCEROL, RTX repeat-containing cytotoxin, ... | 著者 | Minasov, G, Wawrzak, Z, Biancucci, M, Shuvalova, L, Dubrovska, I, Satchell, K.J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2018-10-10 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling. Sci Signal, 11, 2018
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4N5R
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![BU of 4n5r by Molmil](/molmil-images/mine/4n5r) | Hen egg-white lysozyme phased using free-electron laser data | 分子名称: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, GADOLINIUM ATOM, Lysozyme C | 著者 | Barends, T.R.M, Foucar, L, Botha, S, Doak, R.B, Shoeman, R.L, Nass, K, Koglin, J.E, Williams, G.J, Boutet, S, Messerschmidt, M, Schlichting, I. | 登録日 | 2013-10-10 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | De novo protein crystal structure determination from X-ray free-electron laser data. Nature, 505, 2014
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4DJ2
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![BU of 4dj2 by Molmil](/molmil-images/mine/4dj2) | Unwinding the Differences of the Mammalian PERIOD Clock Proteins from Crystal Structure to Cellular Function | 分子名称: | Period circadian protein homolog 1 | 著者 | Kucera, N, Schmalen, I, Hennig, S, Oellinger, R, Strauss, H.M, Grudziecki, A, Wieczorek, C, Kramer, A, Wolf, E. | 登録日 | 2012-02-01 | 公開日 | 2012-02-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function. Proc.Natl.Acad.Sci.USA, 109, 2012
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5V5U
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![BU of 5v5u by Molmil](/molmil-images/mine/5v5u) | Crystal structure of leucine-rich protein regulator, ElrR, from Enterococcus faecalis | 分子名称: | Conserved domain protein | 著者 | De Groote, M.C.R, Camargo, I.L, Serror, P, Horjales, E. | 登録日 | 2017-03-15 | 公開日 | 2018-09-19 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.278 Å) | 主引用文献 | Crystal structure of leucine-rich protein regulator, ElrR, from Enterococcus faecalis To be published
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4MSI
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4DJA
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![BU of 4dja by Molmil](/molmil-images/mine/4dja) | Crystal structure of a prokaryotic (6-4) photolyase PhrB from Agrobacterium Tumefaciens with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore at 1.45A resolution | 分子名称: | 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Scheerer, P, Zhang, F, Oberpichler, I, Lamparter, T, Krauss, N. | 登録日 | 2012-02-01 | 公開日 | 2013-04-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structure of a prokaryotic (6-4) photolyase with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore. Proc.Natl.Acad.Sci.USA, 110, 2013
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5V11
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3T1X
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4DES
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4A3P
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![BU of 4a3p by Molmil](/molmil-images/mine/4a3p) | Structure of USP15 DUSP-UBL deletion mutant | 分子名称: | ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15 | 著者 | Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L. | 登録日 | 2011-10-03 | 公開日 | 2011-11-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains. FEBS Lett., 585, 2011
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5UKQ
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4NQM
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![BU of 4nqm by Molmil](/molmil-images/mine/4nqm) | Crystal Structure of the first bromodomain of human BRD4 in complex with a triazolo-phthalazine ligand | 分子名称: | 2-chloro-N-[5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-(morpholin-4-yl)phenyl]benzenesulfonamide, Bromodomain-containing protein 4, SUCCINIC ACID | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-11-25 | 公開日 | 2013-12-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal Structure of the first bromodomain of human BRD4 in complex with a triazolo-phthalazine ligand To be Published
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4NNC
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![BU of 4nnc by Molmil](/molmil-images/mine/4nnc) | Ternary complex of ObcA with C4-CoA adduct and oxalate | 分子名称: | (3S)-3-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-3-oxidanyl-butanoic acid, COBALT (II) ION, OBCA, ... | 著者 | Oh, J.T, Goo, E, Hwang, I, Rhee, S. | 登録日 | 2013-11-17 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.279 Å) | 主引用文献 | Structural Basis for Bacterial Quorum Sensing-mediated Oxalogenesis. J.Biol.Chem., 289, 2014
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4NPU
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3SQP
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![BU of 3sqp by Molmil](/molmil-images/mine/3sqp) | Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity | 分子名称: | 5-methylphenazin-1(5H)-one, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Fritz-Wolf, K, Schirmer, R.H, Koenig, I, Goebel, U. | 登録日 | 2011-07-06 | 公開日 | 2011-09-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue. Redox Rep., 16, 2011
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4NR9
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![BU of 4nr9 by Molmil](/molmil-images/mine/4nr9) | Crystal Structure of the bromodomain of human BAZ2B in complex with acetylated lysine | 分子名称: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B, N(6)-ACETYLLYSINE | 著者 | Chaikuad, A, Felletar, I, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-11-26 | 公開日 | 2013-12-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain. J.Med.Chem., 56, 2013
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3ZRI
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4NV8
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![BU of 4nv8 by Molmil](/molmil-images/mine/4nv8) | Crystal Structure of Mesorhizobium Loti Arylamine N-acetyltransferase F42W Mutant | 分子名称: | Arylamine N-acetyltransferase | 著者 | Xu, X.M, Haouz, A, Weber, P, Li de la sierra-gallay, I, Kubiak, X, Dupret, J.-M, Rodrigues-lima, F. | 登録日 | 2013-12-05 | 公開日 | 2015-01-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A. Acta Crystallogr.,Sect.D, 71, 2015
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4CAW
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![BU of 4caw by Molmil](/molmil-images/mine/4caw) | Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a pyrazole sulphonamide ligand | 分子名称: | 2,6-DICHLORO-4-(2-PIPERAZIN-1-YLPYRIDIN-4-YL)-N-(1,5-DIMETHYL,3-ISOBUTYL-1H-PYRAZOL-4-YL)BENZENESULFONAMIDE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA | 著者 | Robinson, D.A, Fang, W, Raimi, O.G, Blair, D.E, Harrison, J, Ruda, G.F, Lockhart, D.E.A, Torrie, L.S, Wyatt, P.G, Gilbert, I.H, Van Aalten, D.M.F. | 登録日 | 2013-10-09 | 公開日 | 2014-09-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | N-Myristoyltransferase is a Cell Wall Target in Aspergillus Fumigatus. Acs Chem.Biol., 10, 2015
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4CAX
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![BU of 4cax by Molmil](/molmil-images/mine/4cax) | Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a pyrazole sulphonamide ligand (DDD85646) | 分子名称: | 2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA | 著者 | Raimi, O.G, Robinson, D.A, Fang, W, Blair, D.E, Harrison, J, Ruda, G.F, Lockhart, D.E.A, Torrie, L.S, Wyatt, P.G, Gilbert, I.H, Van Aalten, D.M.F. | 登録日 | 2013-10-09 | 公開日 | 2014-09-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | N-Myristoyltransferase is a Cell Wall Target in Aspergillus Fumigatus. Acs Chem.Biol., 10, 2015
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