5W6L

Crystal Structure of RRSP, a MARTX Toxin Effector Domain from Vibrio vulnificus CMCP6

Summary for 5W6L

• Entry DOI: 10.2210/pdb5w6l/pdb
• Descriptor: RTX repeat-containing cytotoxin, GLYCEROL, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, rrsp, martx toxin, effector domain, toxin
• Biological source: Vibrio vulnificus
• Total number of polymer chains: 2
• Total formula weight: 116016.06

Authors

Minasov, G.,Wawrzak, Z.,Biancucci, M.,Shuvalova, L.,Dubrovska, I.,Satchell, K.J.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-06-16, release date: 2018-06-27, Last modification date: 2018-10-10)

• Primary citation: Biancucci, M.,Minasov, G.,Banerjee, A.,Herrera, A.,Woida, P.J.,Kieffer, M.B.,Bindu, L.,Abreu-Blanco, M.,Anderson, W.F.,Gaponenko, V.,Stephen, A.G.,Holderfield, M.,Satchell, K.J.F.; The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling.; Sci Signal, 11:-, 2018; PubMed: 30279169; DOI: 10.1126/scisignal.aat8335

Experimental method

X-RAY DIFFRACTION (3.45 Å)