7SZO
 
 | | Structure of a bacterial fimbrial tip containing FocH | | 分子名称: | Chaperone protein FimC, FimF protein, FimG, ... | | 著者 | Stenkamp, R.E, Le Trong, I, Aprikian, P, Sokurenko, E.V. | | 登録日 | 2021-11-29 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Recombinant FimH Adhesin Demonstrates How the Allosteric Catch Bond Mechanism Can Support Fast and Strong Bacterial Attachment in the Absence of Shear.
J.Mol.Biol., 434, 2022
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4UQM
 | | Crystal structure determination of uracil-DNA N-glycosylase (UNG) from Deinococcus radiodurans in complex with DNA - new insights into the role of the Leucine-loop for damage recognition and repair | | 分子名称: | 5'-D(*CP*CP*TP*AP*TP*CP*CP*AP*AAB*GP*TP*CP*TP*CP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*GP*AP*CP*AP*TP*GP*GP*AP*CP*AP*G)-3', CHLORIDE ION, ... | | 著者 | Pedersen, H.L, Johnson, K.A, McVey, C.E, Leiros, I, Moe, E. | | 登録日 | 2014-06-24 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure determination of uracil-DNA N-glycosylase from Deinococcus radiodurans in complex with DNA.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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6FJM
 | | tubulin-Disorazole Z complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Disorazole Z, ... | | 著者 | Menchon, G, Prota, A.E, Lucena Agell, D, Bucher, P, Jansen, R, Irschik, H, Mueller, R, Paterson, I, Diaz, J.F, Altmann, K.-H, Steinmetz, M.O. | | 登録日 | 2018-01-22 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.
Nat Commun, 9, 2018
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1ZUA
 | | Crystal Structure Of AKR1B10 Complexed With NADP+ And Tolrestat | | 分子名称: | Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT | | 著者 | Gallego, O, Ruiz, F.X, Ardevol, A, Dominguez, M, Alvarez, R, de Lera, A.R, Rovira, C, Farres, J, Fita, I, Pares, X. | | 登録日 | 2005-05-30 | | 公開日 | 2006-11-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10.
Proc.Natl.Acad.Sci.USA, 104, 2007
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6EUB
 | | The fibrinogen-like domain of human Angptl4 | | 分子名称: | Angiopoietin-related protein 4, PENTAETHYLENE GLYCOL | | 著者 | Biterova, E.I, Esmaeeli, M, Alanen, H.I, Saaranen, M, Ruddock, L.W. | | 登録日 | 2017-10-30 | | 公開日 | 2018-05-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease.
Sci Rep, 8, 2018
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6EUE
 | | Rivastigmine analogue bound to Tc ACHE. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, PENTAETHYLENE GLYCOL | | 著者 | De la Mora, E, Brazzolotto, X, Dighe, S.N, Silman, I, Weik, M, Ross, B. | | 登録日 | 2017-10-30 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model
Commun Chem, 2019
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1GCD
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1ZW3
 | | Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652 | | 分子名称: | Talin 1, Vinculin | | 著者 | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | 登録日 | 2005-06-03 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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6F8Y
 | | Crystal structure of P. abyssi Sua5 complexed with L-threonine | | 分子名称: | THREONINE, Threonylcarbamoyl-AMP synthase | | 著者 | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | | 登録日 | 2017-12-13 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification.
RNA, 24, 2018
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200D
 | | STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE | | 分子名称: | DNA (5'-D(*TP*AP*AP*CP*CP*C)-3') | | 著者 | Kang, C, Berger, I, Lockshin, C, Ratliff, R, Moyzis, R, Rich, A. | | 登録日 | 1995-02-16 | | 公開日 | 1995-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Stable loop in the crystal structure of the intercalated four-stranded cytosine-rich metazoan telomere.
Proc.Natl.Acad.Sci.USA, 92, 1995
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1GPN
 | | STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH HUPERZINE B AT 2.35A RESOLUTION | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, HUPERZINE B | | 著者 | Dvir, H, Harel, M, Jiang, H.L, Silman, I, Sussman, J.L. | | 登録日 | 2001-11-07 | | 公開日 | 2002-08-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | X-Ray Structures of Torpedo Californica Acetylcholinesterase Complexed with (+)-Huperzine a and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement
Biochemistry, 41, 2002
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1GQZ
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1GPB
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1ZUU
 | | Crystal structure of the yeast Bzz1 first SH3 domain at 0.97-A resolution | | 分子名称: | BZZ1 protein, MAGNESIUM ION, UNKNOWN ATOM OR ION | | 著者 | Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | | 登録日 | 2005-06-01 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | Structural genomics of yeast SH3 domains
To be Published
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4WE2
 | | Donor strand complemented FaeG of F4ab fimbriae | | 分子名称: | K88 fimbrial protein AB | | 著者 | Moonens, K, Van den Broeck, I, De Kerpel, M, Deboeck, F, Raymaekers, H, Remaut, H, De Greve, H. | | 登録日 | 2014-09-09 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and Functional Insight into the Carbohydrate Receptor Binding of F4 Fimbriae-producing Enterotoxigenic Escherichia coli.
J.Biol.Chem., 290, 2015
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1ZW7
 | | Elimination of the C-cap in Ubiquitin Structure, Dynamics and Thermodynamic Consequences | | 分子名称: | Ubiquitin | | 著者 | Ermolenko, D.N, Dangi, B, Gronenborn, A.M, Makhatadze, G.I. | | 登録日 | 2005-06-03 | | 公開日 | 2006-05-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Elimination of the C-cap in ubiquitin-structure, dynamics and thermodynamic consequences.
Biophys.Chem., 126, 2007
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4MAS
 | | High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol | | 分子名称: | 3,5,3',5'-TETRACHLORO-BIPHENYL-4,4'-DIOL, Transthyretin | | 著者 | Connelly, S, Bradbury, N.C, Wilson, I.A. | | 登録日 | 2013-08-16 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | High Resolution Structure of Wild Type Human Transthyretin in Complex with 3,3',5,5'-tetrachloro-[1,1'-biphenyl]-4,4'diol
To be Published
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1H55
 | | STRUCTURE OF HORSERADISH PEROXIDASE C1A COMPOUND II | | 分子名称: | ACETATE ION, CALCIUM ION, OXYGEN ATOM, ... | | 著者 | Berglund, G.I, Carlsson, G.H, Hajdu, J, Smith, A.T, Szoke, H, Henriksen, A. | | 登録日 | 2001-05-18 | | 公開日 | 2002-06-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | The Catalytic Pathway of Horseradish Peroxidase at High Resolution
Nature, 417, 2002
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1ZVZ
 | | Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844 | | 分子名称: | Talin 1, Vinculin | | 著者 | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | 登録日 | 2005-06-03 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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4W5W
 | | Rubisco activase from Arabidopsis thaliana | | 分子名称: | Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic, SULFATE ION | | 著者 | Hasse, D, Larsson, A.M, Andersson, I. | | 登録日 | 2014-08-19 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of Arabidopsis thaliana Rubisco activase
Acta Crystallogr.,Sect.D, 71, 2015
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1ZW2
 | | Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369 | | 分子名称: | Vinculin, talin | | 著者 | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | 登録日 | 2005-06-03 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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1H5E
 | | X-ray induced reduction of horseradish peroxidase C1A Compound III (11-22% dose) | | 分子名称: | ACETATE ION, CALCIUM ION, PEROXIDASE C1A, ... | | 著者 | Berglund, G.I, Carlsson, G.H, Hajdu, J, Smith, A.T, Szoke, H, Henriksen, A. | | 登録日 | 2001-05-21 | | 公開日 | 2002-05-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Catalytic Pathway of Horseradish Peroxidase at High Resolution
Nature, 417, 2002
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2AE5
 | | Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism | | 分子名称: | GLYCEROL, Glutaryl 7-Aminocephalosporanic Acid Acylase, SULFATE ION | | 著者 | Kim, J.K, Yang, I.S, Shin, H.J, Cho, K.J, Ryu, E.K, Kim, S.H, Park, S.S, Kim, K.H. | | 登録日 | 2005-07-21 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries.
Proc.Natl.Acad.Sci.USA, 103, 2006
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4UX6
 | | The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS) | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, NITRIC OXIDE SYNTHASE, INDUCIBLE, ... | | 著者 | Cheshire, D.R, Andrews, G, Beaton, H.G, Birkinshaw, T, Boughton-Smith, N, Connolly, S, Cook, T.R, Cooper, A, Cooper, S.L, Cox, D, Dixon, J, Gensmantel, N, Hamley, P.J, Harrison, R, Hartopp, P, Kack, H, Luker, T, Mete, A, Millichip, I, Nicholls, D.J, Pimm, A.D, St-Gallay, S.A, Wallace, A.V. | | 登録日 | 2014-08-19 | | 公開日 | 2014-10-08 | | 最終更新日 | 2018-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos).
Bioorg.Med.Chem.Lett., 21, 2011
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219L
 | | PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, T4 LYSOZYME | | 著者 | Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W. | | 登録日 | 1996-09-23 | | 公開日 | 1996-12-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme.
Protein Sci., 5, 1996
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