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6EUE

Rivastigmine analogue bound to Tc ACHE.

Summary for 6EUE
Entry DOI10.2210/pdb6eue/pdb
DescriptorAcetylcholinesterase, PENTAETHYLENE GLYCOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordscholinesterase, alzheimer disease, organophosphate, carbamylated, hydrolase
Biological sourceTetronarce californica (Pacific electric ray)
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Total number of polymer chains1
Total formula weight62051.02
Authors
De la Mora, E.,Brazzolotto, X.,Dighe, S.N.,Silman, I.,Weik, M.,Ross, B. (deposition date: 2017-10-30, release date: 2018-11-14, Last modification date: 2020-07-29)
Primary citationDighe, S.N.,De la Mora, E.,Chan, S.,Kantham, S.,McColl, G.,Veliyat, S.K.,Miles, J.A.,McGeary, R.P.,Silman, I.,Weik, M.,Parat, M.P.,Brazzolotto, X.,Ross, B.
Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model
Commun Chem, 2019
Cited by
DOI: 10.1038/s42004-019-0133-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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