6EUE
Rivastigmine analogue bound to Tc ACHE.
Summary for 6EUE
Entry DOI | 10.2210/pdb6eue/pdb |
Descriptor | Acetylcholinesterase, PENTAETHYLENE GLYCOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | cholinesterase, alzheimer disease, organophosphate, carbamylated, hydrolase |
Biological source | Tetronarce californica (Pacific electric ray) More |
Total number of polymer chains | 1 |
Total formula weight | 62051.02 |
Authors | De la Mora, E.,Brazzolotto, X.,Dighe, S.N.,Silman, I.,Weik, M.,Ross, B. (deposition date: 2017-10-30, release date: 2018-11-14, Last modification date: 2020-07-29) |
Primary citation | Dighe, S.N.,De la Mora, E.,Chan, S.,Kantham, S.,McColl, G.,Veliyat, S.K.,Miles, J.A.,McGeary, R.P.,Silman, I.,Weik, M.,Parat, M.P.,Brazzolotto, X.,Ross, B. Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model Commun Chem, 2019 Cited by DOI: 10.1038/s42004-019-0133-4PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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