6EUE

Rivastigmine analogue bound to Tc ACHE.

Summary for 6EUE

• Entry DOI: 10.2210/pdb6eue/pdb
• Descriptor: Acetylcholinesterase, PENTAETHYLENE GLYCOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: cholinesterase, alzheimer disease, organophosphate, carbamylated, hydrolase
• Biological source: Tetronarce californica (Pacific electric ray); More
• Total number of polymer chains: 1
• Total formula weight: 62051.02

Authors

De la Mora, E.,Brazzolotto, X.,Dighe, S.N.,Silman, I.,Weik, M.,Ross, B. (deposition date: 2017-10-30, release date: 2018-11-14, Last modification date: 2020-07-29)

• Primary citation: Dighe, S.N.,De la Mora, E.,Chan, S.,Kantham, S.,McColl, G.,Veliyat, S.K.,Miles, J.A.,McGeary, R.P.,Silman, I.,Weik, M.,Parat, M.P.,Brazzolotto, X.,Ross, B.; Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model; Commun Chem, 2019; DOI: 10.1038/s42004-019-0133-4

Experimental method

X-RAY DIFFRACTION (2 Å)