4UQM

Crystal structure determination of uracil-DNA N-glycosylase (UNG) from Deinococcus radiodurans in complex with DNA - new insights into the role of the Leucine-loop for damage recognition and repair

Summary for 4UQM

• Entry DOI: 10.2210/pdb4uqm/pdb
• Descriptor: URACIL-DNA GLYCOSYLASE, 5'-D(*CP*CP*TP*AP*TP*CP*CP*AP*AAB*GP*TP*CP*TP*CP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*GP*AP*CP*AP*TP*GP*GP*AP*CP*AP*G)-3', ... (6 entities in total)
• Functional Keywords: hydrolase-dna complex, base excision repair, radiation resistance, dna damage, dna repair, protein-dna complex, hydrolase/dna
• Biological source: DEINOCOCCUS RADIODURANS; More
• Cellular location: Cytoplasm : Q9RWH9
• Total number of polymer chains: 3
• Total formula weight: 37596.33

Authors

Pedersen, H.L.,Johnson, K.A.,McVey, C.E.,Leiros, I.,Moe, E. (deposition date: 2014-06-24, release date: 2015-08-12, Last modification date: 2024-01-10)

• Primary citation: Pedersen, H.L.,Johnson, K.A.,McVey, C.E.,Leiros, I.,Moe, E.; Structure determination of uracil-DNA N-glycosylase from Deinococcus radiodurans in complex with DNA.; Acta Crystallogr. D Biol. Crystallogr., 71:2137-2149, 2015; PubMed: 26457437; DOI: 10.1107/S1399004715014157

Experimental method

X-RAY DIFFRACTION (1.35 Å)