4UQM
Crystal structure determination of uracil-DNA N-glycosylase (UNG) from Deinococcus radiodurans in complex with DNA - new insights into the role of the Leucine-loop for damage recognition and repair
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | URACIL-DNA GLYCOSYLASE | polymer | 247 | 27794.5 | 1 | UniProt (Q9RWH9) Pfam (PF03167) | DEINOCOCCUS RADIODURANS | UDG, URACIL DNA GLYCOSYLASE |
| 2 | B (B) | 5'-D(*CP*CP*TP*AP*TP*CP*CP*AP*AAB*GP*TP*CP*TP*CP*CP*G)-3' | polymer | 16 | 4677.0 | 1 | SYNTHETIC CONSTRUCT | ||
| 3 | C (C) | 5'-D(*GP*CP*GP*GP*AP*GP*AP*CP*AP*TP*GP*GP*AP*CP*AP*G)-3' | polymer | 16 | 4997.3 | 1 | SYNTHETIC CONSTRUCT | ||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F, G, H (A, B, C) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A: 1 - 247 (UniProt: Q9RWH9)
| PDB | External Database | Details |
|---|---|---|
| Ala 150 | Gly 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37468.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 127.5 | |
| All* | Total formula weight | 37596.3 |
