8I89
| Crystal structure of Cph001-D189N in complex with VIO | 分子名称: | DI(HYDROXYETHYL)ETHER, KBE-DPP-SER-SER-UAL-5OH, Viomycin kinase | 著者 | Chang, C.Y, Toh, S.I, Elaine K, J, Hsiao, P.Y. | 登録日 | 2023-02-03 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin. Commun Biol, 6, 2023
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8I8G
| Crystal structure of Cph001-D189N in complex with CMN IIA and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, KBE-DPP-UAL-MYN-DPP-SER, Viomycin kinase | 著者 | Chang, C.Y, Toh, S.I, Elaine K, J, Hsiao, P.Y. | 登録日 | 2023-02-04 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin. Commun Biol, 6, 2023
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8I8H
| Crystal structure of Cph001-D189N in complex with VIO and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, KBE-DPP-SER-SER-UAL-5OH, ... | 著者 | Chang, C.Y, Toh, S.I, Elaine K, J, Hsiao, P.Y. | 登録日 | 2023-02-04 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin. Commun Biol, 6, 2023
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7Q89
| OleP mutant G92W in complex with 6DEB | 分子名称: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | 著者 | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | 登録日 | 2021-11-10 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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4F61
| Tubulin:Stathmin-like domain complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Gigant, B, Mignot, I, Knossow, M. | 登録日 | 2012-05-14 | 公開日 | 2012-07-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4.17 Å) | 主引用文献 | Design and characterization of modular scaffolds for tubulin assembly. J.Biol.Chem., 287, 2012
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1SNR
| Nitric oxide bound to Cu nitrite reductase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, COPPER (I) ION, ... | 著者 | Tocheva, E.I, Rosell, F.I, Mauk, A.G, Murphy, M.E. | 登録日 | 2004-03-11 | 公開日 | 2004-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Side-on copper-nitrosyl coordination by nitrite reductase. Science, 304, 2004
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7Q6X
| OleP mutant S240Y in complex with 6DEB | 分子名称: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | 著者 | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | 登録日 | 2021-11-09 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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6WFW
| Crystal structure of Fab364 in complex with NPNA2 peptide from circumsporozoite protein | 分子名称: | Fab364 heavy chain, Fab364 light chain, Immunoglobulin G-binding protein G, ... | 著者 | Pholcharee, T, Oyen, D, Wilson, I.A. | 登録日 | 2020-04-04 | 公開日 | 2020-07-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum. Nat Commun, 12, 2021
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7Q6R
| OleP mutant E89Y in complex with 6DEB | 分子名称: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | 著者 | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | 登録日 | 2021-11-09 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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5K91
| Crystal structure of dimeric chlorite dismutase from Cyanothece sp. PCC7425 in complex with fluoride | 分子名称: | Chlorite dismutase, FLUORIDE ION, GLYCEROL, ... | 著者 | Puehringer, D, Schaffner, I, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | 登録日 | 2016-05-31 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies. ACS Catal, 7, 2017
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5KDO
| Heterotrimeric complex of the 4 alanine insertion variant of the Gi alpha1 subunit and the Gbeta1-Ggamma1 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | 著者 | Kaya, A.I, Lokits, A.D, Gilbert, J, Iverson, T.M, Meiler, J, Hamm, H.E. | 登録日 | 2016-06-08 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor. J.Biol.Chem., 291, 2016
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6WPA
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6WIY
| Crystal structure of Fab 54-1G05 | 分子名称: | Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, GLYCEROL | 著者 | Wu, N.C, Wilson, I.A. | 登録日 | 2020-04-11 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host Microbe, 28, 2020
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7OJ2
| Bacillus subtilis IMPDH in complex with Ap4A | 分子名称: | GLYCEROL, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION | 著者 | Giammarinaro, P.I, Bange, G. | 登録日 | 2021-05-13 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
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7OJ1
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7QHH
| Desensitized state of GluA1/2 AMPA receptor in complex with TARP-gamma 8 (TMD-LBD) | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, GLUTAMIC ACID, ... | 著者 | Herguedas, B, Kohegyi, B, Dohrke, J.N, Watson, J.F, Zhang, D, Ho, H, Shaikh, S, Lape, R, Krieger, J.M, Greger, I.H. | 登録日 | 2021-12-12 | 公開日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor. Nat Commun, 13, 2022
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7QHB
| Active state of GluA1/2 in complex with TARP gamma 8, L-glutamate and CTZ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, CYCLOTHIAZIDE, ... | 著者 | Herguedas, B, Kohegyi, B, Zhang, D, Greger, I.H. | 登録日 | 2021-12-11 | 公開日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor. Nat Commun, 13, 2022
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6WM5
| Structure of a phosphatidylinositol-phosphate synthase (PIPS) from Mycobacterium kansasii | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, 3,3',3''-phosphanetriyltripropanoic acid, ... | 著者 | Belcher Dufrisne, M, Jorge, C.D, Timoteo, C.G, Petrou, V.I, Ashraf, K.U, Banerjee, S, Clarke, O.B, Santos, H, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | 登録日 | 2020-04-20 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | 主引用文献 | Structural and Functional Characterization of Phosphatidylinositol-Phosphate Biosynthesis in Mycobacteria. J.Mol.Biol., 432, 2020
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5K90
| Crystal structure of dimeric chlorite dismutase from Cyanothece sp. PCC7425 in complex with isothiocyanate | 分子名称: | Chlorite dismutase, GLYCEROL, MAGNESIUM ION, ... | 著者 | Puehringer, D, Schaffner, I, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | 登録日 | 2016-05-31 | 公開日 | 2017-06-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies. ACS Catal, 7, 2017
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6TK2
| Femtosecond to millisecond structural changes in a light-driven sodium pump: 1ms structure of KR2 with extrapolated, light and dark datasets | 分子名称: | EICOSANE, RETINAL, SODIUM ION, ... | 著者 | Skopintsev, P, Ehrenberg, D, Weinert, T, James, D, Kar, R, Johnson, P, Ozerov, D, Furrer, A, Martiel, I, Dworkowski, F, Nass, K, Knopp, G, Cirelli, C, Gashi, D, Mous, S, Wranik, M, Gruhl, T, Kekilli, D, Bruenle, S, Deupi, X, Schertler, G.F.X, Benoit, R, Panneels, V, Nogly, P, Schapiro, I, Milne, C, Heberle, J, Standfuss, J. | 登録日 | 2019-11-28 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Femtosecond-to-millisecond structural changes in a light-driven sodium pump. Nature, 583, 2020
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6GN7
| X-ray structure of the complex between human alpha thrombin and NU172, a duplex/quadruplex 26-mer DNA aptamer, in the presence of sodium ions. | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Troisi, R, Russo Krauss, I, Sica, F. | 登録日 | 2018-05-30 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer. Nucleic Acids Res., 46, 2018
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1WQJ
| Structural Basis for the Regulation of Insulin-Like Growth Factors (IGFs) by IGF Binding Proteins (IGFBPs) | 分子名称: | Insulin-like growth factor IB, Insulin-like growth factor binding protein 4 | 著者 | Siwanowicz, I, Popowicz, G.M, Wisniewska, M, Huber, R, Kuenkele, K.P, Lang, K, Engh, R.A, Holak, T.A. | 登録日 | 2004-09-29 | 公開日 | 2005-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the regulation of insulin-like growth factors by IGF binding proteins Structure, 13, 2005
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6TK1
| Femtosecond to millisecond structural changes in a light-driven sodium pump: 20ms structure of KR2 with extrapolated, light and dark datasets | 分子名称: | EICOSANE, RETINAL, SODIUM ION, ... | 著者 | Skopintsev, P, Ehrenberg, D, Weinert, T, James, D, Kar, R, Johnson, P, Ozerov, D, Furrer, A, Martiel, I, Dworkowski, F, Nass, K, Knopp, G, Cirelli, C, Gashi, D, Mous, S, Wranik, M, Gruhl, T, Kekilli, D, Bruenle, S, Deupi, X, Schertler, G.F.X, Benoit, R, Panneels, V, Nogly, P, Schapiro, I, Milne, C, Heberle, J, Standfuss, J. | 登録日 | 2019-11-28 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Femtosecond-to-millisecond structural changes in a light-driven sodium pump. Nature, 583, 2020
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5KE4
| Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 6 nicotinic acetylcholine receptor in complex with 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)- N,N-dimethylethanamine (BPC) | 分子名称: | 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)-N,N-dimethylethanamine, Soluble acetylcholine receptor | 著者 | Bobango, J, Wu, J, Talley, I.T, Ralston, R, Sankaran, B, Talley, T.T. | 登録日 | 2016-06-09 | 公開日 | 2016-07-06 | 実験手法 | X-RAY DIFFRACTION (2.554 Å) | 主引用文献 | Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 6 nicotinic acetylcholine receptor in complex with 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)-
N,N-dimethylethanamine (BPC) To Be Published
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6WTS
| CryoEM structure of the C. sordellii lethal toxin TcsL in complex with SEMA6A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SEMA6A, ... | 著者 | Kucharska, I, Rubinstein, J.L, Julien, J.P. | 登録日 | 2020-05-03 | 公開日 | 2020-07-08 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins. Cell, 182, 2020
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