6WTS

CryoEM structure of the C. sordellii lethal toxin TcsL in complex with SEMA6A

Summary for 6WTS

Entry DOI	10.2210/pdb6wts/pdb
EMDB information	21898 21899
Descriptor	SEMA6A, TcsL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	cryoem, signaling protein-toxin complex, signaling protein/toxin
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	193188.73
Authors	Kucharska, I.,Rubinstein, J.L.,Julien, J.P. (deposition date: 2020-05-03, release date: 2020-07-08, Last modification date: 2020-08-05)
Primary citation	Lee, H.,Beilhartz, G.L.,Kucharska, I.,Raman, S.,Cui, H.,Lam, M.H.Y.,Liang, H.,Rubinstein, J.L.,Schramek, D.,Julien, J.P.,Melnyk, R.A.,Taipale, M. Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins. Cell, 182:345-, 2020 Cited by PubMed: 32589945 DOI: 10.1016/j.cell.2020.06.005 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation