6WTS
CryoEM structure of the C. sordellii lethal toxin TcsL in complex with SEMA6A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | SEMA6A | polymer | 564 | 63857.4 | 2 | UniProt (Q9H2E6) Pfam (PF01403) Pfam (PF01437) | Homo sapiens (Human) | Semaphorin VIA,Sema VIA,Semaphorin-6A-1,SEMA6A-1, Semaphorin-6A |
| 2 | C (C) | TcsL | polymer | 552 | 63315.9 | 1 | UniProt (V5T923) | Paeniclostridium sordellii (Clostridium sordellii) | Lethal Toxin, Cytotoxin L |
| 3 | D, E, F (D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, H, I, J (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A, B: 19 - 570 (UniProt: Q9H2E6)
C: 1285 - 1804 (UniProt: V5T923)
| PDB | External Database | Details |
|---|---|---|
| Glu 17 | - | expression tag |
| Thr 18 | - | expression tag |
| Gly 571 | - | expression tag |
| Ser 572 | - | expression tag |
| Trp 573 | - | expression tag |
| Ser 574 | - | expression tag |
| His 575 | - | expression tag |
| Pro 576 | - | expression tag |
| Gln 577 | - | expression tag |
| Phe 578 | - | expression tag |
| Glu 579 | - | expression tag |
| Lys 580 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 1268 | - | expression tag |
| Ala 1269 | - | expression tag |
| Trp 1270 | - | expression tag |
| Ser 1271 | - | expression tag |
| His 1272 | - | expression tag |
| Pro 1273 | - | expression tag |
| Gln 1274 | - | expression tag |
| Phe 1275 | - | expression tag |
| Glu 1276 | - | expression tag |
| Lys 1277 | - | expression tag |
| Glu 1278 | - | expression tag |
| Asn 1279 | - | expression tag |
| Leu 1280 | - | expression tag |
| Tyr 1281 | - | expression tag |
| Phe 1282 | - | expression tag |
| Gln 1283 | - | expression tag |
| Gly 1284 | - | expression tag |
| Gly 1805 | - | expression tag |
| Ser 1806 | - | expression tag |
| Glu 1807 | - | expression tag |
| Asn 1808 | - | expression tag |
| Leu 1809 | - | expression tag |
| Tyr 1810 | - | expression tag |
| Phe 1811 | - | expression tag |
| Gln 1812 | - | expression tag |
| Gly 1813 | - | expression tag |
| His 1814 | - | expression tag |
| His 1815 | - | expression tag |
| His 1816 | - | expression tag |
| His 1817 | - | expression tag |
| His 1818 | - | expression tag |
| His 1819 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 191030.7 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 193188.7 |
