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PDB: 155 件

4BTQ
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BU of 4btq by Molmil
Coordinates of the bacteriophage phi6 capsid subunits fitted into the cryoEM map EMD-1206
分子名称: MAJOR INNER PROTEIN P1
著者Nemecek, D, Boura, E, Wu, W, Cheng, N, Plevka, P, Qiao, J, Mindich, L, Heymann, J.B, Hurley, J.H, Steven, A.C.
登録日2013-06-18
公開日2013-12-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Subunit Folds and Maturation Pathway of a Dsrna Virus Capsid.
Structure, 21, 2013
2ZME
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BU of 2zme by Molmil
Integrated structural and functional model of the human ESCRT-II complex
分子名称: Vacuolar protein-sorting-associated protein 25, Vacuolar protein-sorting-associated protein 36, Vacuolar-sorting protein SNF8
著者Im, Y.J, Hurley, J.H.
登録日2008-04-17
公開日2008-11-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex
Dev.Cell, 14, 2008
6VME
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BU of 6vme by Molmil
Human ESCRT-I heterotetramer headpiece
分子名称: Multivesicular body subunit 12A, Tumor susceptibility gene 101 protein, Vacuolar protein sorting-associated protein 28 homolog, ...
著者Flower, T.G, Hurley, J.H, Tjahjono, N.
登録日2020-01-27
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission.
Nat.Struct.Mol.Biol., 27, 2020
5HM9
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BU of 5hm9 by Molmil
Crystal structure of MamO protease domain from Magnetospirillum magneticum (apo form)
分子名称: MamO protease domain, poly(UNK)
著者Hershey, D.M, Ren, X, Hurley, J.H, Komeili, A.
登録日2016-01-15
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献MamO Is a Repurposed Serine Protease that Promotes Magnetite Biomineralization through Direct Transition Metal Binding in Magnetotactic Bacteria.
Plos Biol., 14, 2016
5HMA
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BU of 5hma by Molmil
Crystal structure of MamO protease domain from Magnetospirillum magneticum (Ni bound form)
分子名称: CHLORIDE ION, NICKEL (II) ION, Trypsin-like serine protease, ...
著者Hershey, D.M, Ren, X, Hurley, J.H, Komeili, A.
登録日2016-01-15
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献MamO Is a Repurposed Serine Protease that Promotes Magnetite Biomineralization through Direct Transition Metal Binding in Magnetotactic Bacteria.
Plos Biol., 14, 2016
6WCW
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BU of 6wcw by Molmil
Structure of human Rubicon RH domain in complex with GTP-bound Rab7
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7a, ...
著者Bhargava, H.K, Byck, J.M, Farrell, D.P, Anishchenko, I, DiMaio, F, Im, Y.J, Hurley, J.H.
登録日2020-03-31
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex.
Proc.Natl.Acad.Sci.USA, 117, 2020
6NZD
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BU of 6nzd by Molmil
Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator)
分子名称: 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ...
著者Fromm, S.A, Young, L.N, Hurley, J.H.
登録日2019-02-13
公開日2019-11-06
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Science, 366, 2019
7UX3
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BU of 7ux3 by Molmil
Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-05-04
公開日2023-05-10
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (9.6 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
6CYT
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BU of 6cyt by Molmil
HIV-1 TAR loop in complex with Tat:AFF4:P-TEFb
分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ...
著者Schulze Gahmen, U, Hurley, J.H.
登録日2018-04-06
公開日2018-12-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6PAS
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BU of 6pas by Molmil
Inactive State of Manduca sexta soluble guanylate cyclase
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Soluble guanylyl cyclase alpha-1 subunit, Soluble guanylyl cyclase beta-1 subunit
著者Yokom, A.L, Horst, B.G, Marletta, M.A, Hurley, J.H.
登録日2019-06-11
公開日2019-10-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.
Elife, 8, 2019
6PAT
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BU of 6pat by Molmil
Active State of Manduca sexta soluble Guanylate Cyclase
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Soluble guanylyl cyclase alpha-1 subunit, Soluble guanylyl cyclase beta-1 subunit
著者Yokom, A.L, Horst, B.G, Marletta, M.A, Hurley, J.H.
登録日2019-06-11
公開日2019-10-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.
Elife, 8, 2019
8D9R
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BU of 8d9r by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on gamma-Arf1
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9V
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BU of 8d9v by Molmil
gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes
分子名称: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9T
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BU of 8d9t by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on gamma-Arf1
分子名称: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9S
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BU of 8d9s by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1
分子名称: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9U
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BU of 8d9u by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
3G9H
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BU of 3g9h by Molmil
Crystal structure of the C-terminal mu homology domain of Syp1
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Suppressor of yeast profilin deletion
著者Reider, A, Barker, S, Mishra, S, Im, Y.J, Maldonado-Baez, L, Hurley, J, Traub, L, Wendland, B.
登録日2009-02-13
公開日2009-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.
Embo J., 28, 2009
3G9G
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BU of 3g9g by Molmil
Crystal Structure of the N-terminal EFC/F-BAR domain of Syp1
分子名称: Suppressor of yeast profilin deletion
著者Reider, A, Barker, S, Mishra, S, Im, Y.J, Maldonado-Baez, L, Hurley, J, Traub, L, Wendland, B.
登録日2009-02-13
公開日2009-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.
Embo J., 28, 2009
6B9X
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BU of 6b9x by Molmil
Crystal structure of Ragulator
分子名称: Hepatitis B virus x interacting protein, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ...
著者SU, M.-Y, Hurley, J.H.
登録日2017-10-11
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex.
Mol. Cell, 68, 2017
8SQZ
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BU of 8sqz by Molmil
Structure of human ULK1 complex core (2:2:2 stoichiometry) in the PI3KC3-C1 mixture
分子名称: Autophagy-related protein 13, RB1-inducible coiled-coil protein 1, Serine/threonine-protein kinase ULK1
著者Chen, M, Hurley, J.H.
登録日2023-05-04
公開日2023-06-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (5.85 Å)
主引用文献Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv, 2023
8SOR
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BU of 8sor by Molmil
Structure of human PI3KC3-C1 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Beclin 1-associated autophagy-related key regulator, Beclin-1, ...
著者Chen, M, Hurley, J.H.
登録日2023-04-29
公開日2023-06-21
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv, 2023
8SOI
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BU of 8soi by Molmil
Structure of human ULK1 complex core (2:1:1 stoichiometry)
分子名称: Autophagy-related protein 13, RB1-inducible coiled-coil protein 1, Serine/threonine-protein kinase ULK1
著者Chen, M, Hurley, J.H.
登録日2023-04-28
公開日2023-06-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv, 2023
8SRM
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BU of 8srm by Molmil
Structure of human ULK1 complex core (2:2:2 stoichiometry) of the ATG13(450-517) mutant
分子名称: Autophagy-related protein 13, RB1-inducible coiled-coil protein 1, Serine/threonine-protein kinase ULK1
著者Chen, M, Hurley, J.H.
登録日2023-05-05
公開日2023-06-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.46 Å)
主引用文献Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
bioRxiv
6WJ3
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BU of 6wj3 by Molmil
CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the post-GAP state
分子名称: GUANOSINE-5'-DIPHOSPHATE, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ...
著者Fromm, S.A, Hurley, J.H.
登録日2020-04-11
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9.
Nat.Struct.Mol.Biol., 27, 2020
6WJ2
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BU of 6wj2 by Molmil
CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state
分子名称: 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Fromm, S.A, Hurley, J.H.
登録日2020-04-11
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9.
Nat.Struct.Mol.Biol., 27, 2020

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