1IGX
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![BU of 1igx by Molmil](/molmil-images/mine/1igx) | Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1. | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5,8,11,14,17-EICOSAPENTAENOIC ACID, ... | Authors: | Malkowski, M.G, Thuresson, E.D, Smith, W.L, Garavito, R.M. | Deposit date: | 2001-04-18 | Release date: | 2001-12-12 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1. J.Biol.Chem., 276, 2001
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4GYI
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![BU of 4gyi by Molmil](/molmil-images/mine/4gyi) | Crystal structure of the Rio2 kinase-ADP/Mg2+-phosphoaspartate complex from Chaetomium thermophilum | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ferreira-Cerca, S, Sagar, V, Schafer, T, Diop, M, Wesseling, A.M, Lu, H, Chai, E, Hurt, E, LaRonde-LeBlanc, N. | Deposit date: | 2012-09-05 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit. Nat.Struct.Mol.Biol., 19, 2012
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1DXA
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![BU of 1dxa by Molmil](/molmil-images/mine/1dxa) | BENZO[A]PYRENE DIOL EPOXIDE ADDUCT OF DA IN DUPLEX DNA | Descriptor: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA (5'-D(*CP*TP*CP*GP*GP*GP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*CP*AP*CP*GP*AP*G)-3') | Authors: | Yeh, H.J.C, Sayer, J.M, Liu, X, Altieri, A.S, Byrd, R.A, Lakshman, M.K, Yagi, H, Schurter, E.J, Gorenstein, D.G, Jerina, D.M. | Deposit date: | 1995-09-01 | Release date: | 1995-12-07 | Last modified: | 2024-03-13 | Method: | SOLUTION NMR | Cite: | NMR solution structure of a nonanucleotide duplex with a dG mismatch opposite a 10S adduct derived from trans addition of a deoxyadenosine N6-amino group to (+)-(7R,8S,9S,10R)-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene: an unusual syn glycosidic torsion angle at the modified dA Biochemistry, 34, 1995
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3J2I
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![BU of 3j2i by Molmil](/molmil-images/mine/3j2i) | Structure of late pre-60S ribosomal subunits with nuclear export factor Arx1 bound at the peptide exit tunnel | Descriptor: | Eukaryotic translation initiation factor 6, Proliferation-associated protein 2G4 | Authors: | Bradatsch, B, Leidig, C, Granneman, S, Gnaedig, M, Tollervey, D, Boettcher, B, Beckmann, R, Hurt, E. | Deposit date: | 2012-10-04 | Release date: | 2012-11-07 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11.9 Å) | Cite: | Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel. Nat.Struct.Mol.Biol., 19, 2012
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4GYG
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![BU of 4gyg by Molmil](/molmil-images/mine/4gyg) | Crystal structure of the Rio2 kinase from Chaetomium thermophilum | Descriptor: | Rio2 kinase | Authors: | Ferreira-Cerca, S, Sagar, V, Schafer, T, Diop, M, Wesseling, A.M, Lu, H, Chai, E, Hurt, E, LaRonde-LeBlanc, N. | Deposit date: | 2012-09-05 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.482 Å) | Cite: | ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit. Nat.Struct.Mol.Biol., 19, 2012
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1AC9
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![BU of 1ac9 by Molmil](/molmil-images/mine/1ac9) | SOLUTION STRUCTURE OF A DNA DECAMER CONTAINING THE ANTIVIRAL DRUG GANCICLOVIR: COMBINED USE OF NMR, RESTRAINED MOLECULAR DYNAMICS, AND FULL RELAXATION REFINEMENT, 6 STRUCTURES | Descriptor: | DNA | Authors: | Foti, M, Marshalko, S, Schurter, E, Kumar, S, Beardsley, G.P, Schweitzer, B.I. | Deposit date: | 1997-02-17 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a DNA decamer containing the antiviral drug ganciclovir: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement. Biochemistry, 36, 1997
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1GO5
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![BU of 1go5 by Molmil](/molmil-images/mine/1go5) | |
2RFO
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![BU of 2rfo by Molmil](/molmil-images/mine/2rfo) | Crystral Structure of the nucleoporin Nic96 | Descriptor: | Nucleoporin NIC96 | Authors: | Schrader, N, Stelter, P, Flemming, D, Kunze, K, Hurt, E, Vetter, I.R. | Deposit date: | 2007-10-01 | Release date: | 2008-01-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of the nic96 subcomplex organization in the nuclear pore channel. Mol.Cell, 29, 2008
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3PWH
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![BU of 3pwh by Molmil](/molmil-images/mine/3pwh) | Thermostabilised Adenosine A2A Receptor | Descriptor: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a | Authors: | Dore, A.S, Robertson, N, Errey, J.C, Ng, I, Tehan, B, Hurrell, E, Magnani, F, Tate, C.G, Weir, M, Marshall, F.H. | Deposit date: | 2010-12-08 | Release date: | 2011-09-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.296 Å) | Cite: | Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine Structure, 19, 2011
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3RFM
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![BU of 3rfm by Molmil](/molmil-images/mine/3rfm) | Thermostabilised adenosine A2A receptor in complex with caffeine | Descriptor: | Adenosine receptor A2a, CAFFEINE | Authors: | Dore, A.S, Robertson, N, Errey, J.C, Ng, I, Hollenstein, K, Tehan, B, Hurrell, E, Bennett, K, Congreve, M, Magnani, F, Tate, C.G, Weir, M, Marshall, F.H. | Deposit date: | 2011-04-06 | Release date: | 2011-09-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.598 Å) | Cite: | Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine Structure, 19, 2011
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2MVF
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![BU of 2mvf by Molmil](/molmil-images/mine/2mvf) | Structural insight into an essential assembly factor network on the pre-ribosome | Descriptor: | Uncharacterized protein | Authors: | Lee, W, Bassler, J, Paternoga, H, Holdermann, I, Thomas, M, Granneman, S, Barrio-Garcia, C, Nyarko, A, Stier, G, Clark, S.A, Schraivogel, D, Kallas, M, Beckmann, R, Tollervey, D, Barbar, E, Sinning, I, Hurt, E. | Deposit date: | 2014-10-02 | Release date: | 2014-12-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
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3REY
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![BU of 3rey by Molmil](/molmil-images/mine/3rey) | Thermostabilised adenosine A2A receptor in complex with XAC | Descriptor: | Adenosine receptor A2a, N-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetamide | Authors: | Dore, A.S, Robertson, N, Errey, J.C, Ng, I, Hollenstein, K, Tehan, B, Hurrell, E, Bennett, K, Congreve, M, Magnani, F, Tate, C.G, Weir, M, Marshall, F.H. | Deposit date: | 2011-04-05 | Release date: | 2011-09-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.309 Å) | Cite: | Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine Structure, 19, 2011
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3UZC
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![BU of 3uzc by Molmil](/molmil-images/mine/3uzc) | Thermostabilised Adenosine A2A receptor in complex with 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol | Descriptor: | 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol, Adenosine A2A Receptor | Authors: | Congreve, M, Andrews, S.P, Dore, A.S, Hollenstein, K, Hurrell, E, Langmead, C.J, Mason, J.S, Ng, I.W, Zhukov, A, Weir, M, Marshall, F.H. | Deposit date: | 2011-12-07 | Release date: | 2012-03-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.341 Å) | Cite: | Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design J.Med.Chem., 55, 2012
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3UZA
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![BU of 3uza by Molmil](/molmil-images/mine/3uza) | Thermostabilised Adenosine A2A receptor in complex with 6-(2,6-Dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine | Descriptor: | 6-(2,6-dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine, Adenosine receptor A2a | Authors: | Congreve, M, Andrews, S.P, Dore, A.S, Hollenstein, K, Hurrell, E, Langmead, C.J, Mason, J.S, Ng, I.W, Tehan, B, Zhukov, A, Weir, M, Marshall, F.H. | Deposit date: | 2011-12-07 | Release date: | 2012-03-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.273 Å) | Cite: | Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design J.Med.Chem., 55, 2012
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