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PDB: 301 件

5DX7
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Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylic acid
分子名称: 5-(5-chlorothiophen-2-yl)-1,2-oxazole-3-carboxylic acid, MAGNESIUM ION, Malate synthase G
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-09-23
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291, 2016
5BO0
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Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.2-H4 dimer
分子名称: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.2, ...
著者Huang, H, Patel, D.J.
登録日2015-05-26
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
5C9R
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BU of 5c9r by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 3-((4-chlorophenyl)thio)propanoic acid
分子名称: 3-[(4-chlorophenyl)sulfanyl]propanoic acid, MAGNESIUM ION, Malate synthase G
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-06-28
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291, 2016
5CCZ
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Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-amine
分子名称: 3-(4-fluorophenyl)-4-methyl-1H-pyrazol-5-amine, MAGNESIUM ION, Malate synthase G
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-07-02
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.136 Å)
主引用文献Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291, 2016
5C7V
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Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-pyrrole-2-carboxylic acid
分子名称: MAGNESIUM ION, Malate synthase G, PYRROLE-2-CARBOXYLATE
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-06-25
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291, 2016
5CAH
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BU of 5cah by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 6H-thieno[2,3-b]pyrrole-5-carboxylic acid
分子名称: 6H-thieno[2,3-b]pyrrole-5-carboxylic acid, MAGNESIUM ION, Malate synthase G
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-06-29
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Mycobacterium tuberculosis Malate Synthase Structures with Fragments Reveal a Portal for Substrate/Product Exchange.
J. Biol. Chem., 291, 2016
1IK1
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BU of 1ik1 by Molmil
Solution Structure of an RNA Hairpin from HRV-14
分子名称: 5'-R(*GP*GP*UP*AP*CP*UP*AP*UP*GP*UP*AP*CP*CP*A)-3'
著者Huang, H, Alexandrov, A, Chen, X, Barnes III, T.W, Zhang, H, Dutta, K, Pascal, S.M.
登録日2001-05-01
公開日2001-07-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of an RNA hairpin from HRV-14.
Biochemistry, 40, 2001
4O1P
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Crystal Structure of RNase L in complex with 2-5A and AMP-PNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonuclease L, ...
著者Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
登録日2013-12-16
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
4O1O
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Crystal Structure of RNase L in complex with 2-5A
分子名称: Ribonuclease L, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
著者Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
登録日2013-12-16
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
5DQL
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BU of 5dql by Molmil
Crystal Structure of 2-vinyl glyoxylate modified isocitrate lyase from Mycobacterium tuberculosis
分子名称: 4-hydroxy-2-oxobutanoic acid, Isocitrate lyase 1, MAGNESIUM ION
著者Huang, H.-L, Meek, T.D.
登録日2015-09-14
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.782 Å)
主引用文献Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5CC6
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BU of 5cc6 by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-indole-5-carboxylic acid
分子名称: 1H-indole-5-carboxylic acid, MAGNESIUM ION, Malate synthase G
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-07-01
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs
To Be Published
5CC3
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BU of 5cc3 by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 6-bromo-1H-indole-2-carboxylic acid
分子名称: 6-bromanyl-1H-indole-2-carboxylic acid, MAGNESIUM ION, Malate synthase G
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-07-01
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs
To Be Published
5CC7
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BU of 5cc7 by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-indole-6-carboxylic acid
分子名称: 1H-indole-6-carboxylic acid, MAGNESIUM ION, Malate synthase G
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-07-01
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs
To Be Published
5CC5
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BU of 5cc5 by Molmil
Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 1H-indole-3-carboxylic acid
分子名称: 1H-INDOLE-3-CARBOXYLIC ACID, GLYOXYLIC ACID, MAGNESIUM ION, ...
著者Huang, H.-L, Sacchettini, J.C.
登録日2015-07-01
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structures of fragment-bound malate synthase from Mycobacterium tuberculosis provide insights into mechanism and potential inhibitor designs
To Be Published
4Q9Q
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BU of 4q9q by Molmil
Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab
分子名称: (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ...
著者Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
登録日2014-05-01
公開日2014-06-18
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4Q9R
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BU of 4q9r by Molmil
Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab
分子名称: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ...
著者Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
登録日2014-05-01
公開日2014-06-18
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4TQ6
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BU of 4tq6 by Molmil
Structure of a UbiA homolog from Archaeoglobus fulgidus bound to Cd2+
分子名称: CADMIUM ION, prenyltransferase
著者Huang, H, Levin, E.J, Bai, Y, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-06-10
公開日2014-07-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.0678 Å)
主引用文献Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1.
Plos Biol., 12, 2014
2LWP
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BU of 2lwp by Molmil
The NMR solution structure of the the ubiquitin homology domain of mouse BAG-1
分子名称: BAG family molecular chaperone regulator 1
著者Huang, H, Yu, C.
登録日2012-08-05
公開日2013-06-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NMR solution structure of the ubiquitin homology domain of Bcl-2-associated athanogene 1 (BAG-1-UBH) from Mus musculus.
Biochem.Biophys.Res.Commun., 431, 2013
5BNV
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BU of 5bnv by Molmil
Crystal structure of Human MCM2 HBD chaperoning a histone H3-H4 tetramer
分子名称: DNA replication licensing factor MCM2, Histone H3.3, Histone H4, ...
著者Huang, H, Patel, D.J.
登録日2015-05-26
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.795 Å)
主引用文献A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
5Y6O
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BU of 5y6o by Molmil
Crystal structure of DAXX N-terminal four-helix bundle domain (4HB) in complex with ATRX
分子名称: Death domain-associated protein 6,Transcriptional regulator ATRX
著者Huang, H, Patel, D.J.
登録日2017-08-13
公開日2017-10-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of DAXX N-terminal four-helix bundle domain (4HB) in complex with ATRX
Nat Commun, 2017
4KZE
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BU of 4kze by Molmil
Crystal structure of an RNA aptamer in complex with Fab
分子名称: BL3-6 Fab antibody, heavy chain, light chain, ...
著者Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
登録日2013-05-29
公開日2014-06-18
最終更新日2014-07-30
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4KZD
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BU of 4kzd by Molmil
Crystal structure of an RNA aptamer in complex with fluorophore and Fab
分子名称: 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ...
著者Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
登録日2013-05-29
公開日2014-06-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.186 Å)
主引用文献A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
8I22
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BU of 8i22 by Molmil
Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester
分子名称: 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase
著者Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y.
登録日2023-01-13
公開日2024-01-17
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.15 Å)
主引用文献Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester
To Be Published
8I6M
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Acyl-ACP synthetase structure bound to AMP-C18:1
分子名称: ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, MAGNESIUM ION, ...
著者Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y.
登録日2023-01-28
公開日2024-01-31
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Acyl-ACP synthetase structure bound to AMP-C18:1
To Be Published
8I35
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BU of 8i35 by Molmil
Acyl-ACP synthetase structure bound to oleic acid
分子名称: Acyl-acyl carrier protein synthetase, OLEIC ACID
著者Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y.
登録日2023-01-16
公開日2024-01-24
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Acyl-ACP synthetase structure bound to oleic acid
To Be Published

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件を2024-06-12に公開中

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