1ZK9
 
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1WTL
 
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1ZKA
 
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1OOA
 
 | CRYSTAL STRUCTURE OF NF-kB(p50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER | Descriptor: | Nuclear factor NF-kappa-B p105 subunit, RNA aptamer | Authors: | Huang, D.B, Vu, D, Cassiday, L.A, Zimmerman, J.M, Maher III, L.J, Ghosh, G. | Deposit date: | 2003-03-03 | Release date: | 2003-07-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer. Proc.Natl.Acad.Sci.USA, 100, 2003
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1SGS
 
 | Crystal structure of a free kB DNA | Descriptor: | CALCIUM ION, kB DNA | Authors: | Huang, D.B, Phelps, C.B, Fusco, A.J, Ghosh, G. | Deposit date: | 2004-02-24 | Release date: | 2004-03-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB. J.Mol.Biol., 346, 2005
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4JHB
 
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4JGM
 
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1BFT
 
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1BFS
 
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1GJI
 
 | Crystal structure of c-Rel bound to DNA | Descriptor: | C-REL PROTO-ONCOGENE PROTEIN, IL-2 CD28RE DNA | Authors: | Huang, D.B, Chen, Y.Q, Ruetsche, M, Phelps, C.B, Ghosh, G. | Deposit date: | 2001-05-30 | Release date: | 2002-05-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2. Structure, 9, 2001
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1LE9
 
 | Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti | Descriptor: | 5'-D(*AP*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*T)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ... | Authors: | Benjamin, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G. | Deposit date: | 2002-04-09 | Release date: | 2003-04-15 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. J.Biol.Chem., 277, 2002
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2V2T
 
 | X-ray structure of a NF-kB p50-RelB-DNA complex | Descriptor: | 5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*CP*CP*CP)-3', NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT, TRANSCRIPTION FACTOR RELB | Authors: | Moorthy, A.K, Huang, D.B, Wang, V.Y, Vu, D, Ghosh, G. | Deposit date: | 2007-06-07 | Release date: | 2007-07-03 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | X-Ray Structure of a NF-kappaB p50/Relb/DNA Complex Reveals Assembly of Multiple Dimers on Tandem kappaB Sites. J.Mol.Biol., 373, 2007
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3BJL
 
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3DO7
 
 | X-ray structure of a NF-kB p52/RelB/DNA complex | Descriptor: | 5'-D(*DCP*DGP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DCP*DC)-3', Avian reticuloendotheliosis viral (V-rel) oncogene related B, Nuclear factor NF-kappa-B p100 subunit | Authors: | Fusco, A, Huang, D.B, Miller, D, Vu, D, Ghosh, G. | Deposit date: | 2008-07-03 | Release date: | 2009-07-21 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA TO BE PUBLISHED
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3JV0
 
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3JV5
 
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3JSS
 
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3JUZ
 
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4BJL
 
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4E3C
 
 | X-ray crystal structure of human IKK2 in an active conformation | Descriptor: | Inhibitor of nuclear factor kappa-B kinase subunit beta | Authors: | Polley, S, Huang, D.B, Hauenstein, A.V, Ghosh, G, Huxford, T. | Deposit date: | 2012-03-09 | Release date: | 2013-06-19 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.98 Å) | Cite: | X-ray crystal structure of human IKK2 in an active conformation Plos.Biol., 2013
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1VKX
 
 | CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA | Descriptor: | DNA (5'-D(*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*C)-3'), PROTEIN (NF-KAPPA B P50 SUBUNIT), ... | Authors: | Chen, F, Huang, D.B, Ghosh, G. | Deposit date: | 1997-09-17 | Release date: | 1998-12-09 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature, 391, 1998
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1K3Z
 
 | X-ray crystal structure of the IkBb/NF-kB p65 homodimer complex | Descriptor: | Transcription factor p65, transcription factor inhibitor I-kappa-B-beta | Authors: | Shiva, M, Huang, D.B, Chen, Y, Huxford, T, Ghosh, S, Ghosh, G. | Deposit date: | 2001-10-04 | Release date: | 2002-10-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex. J.Biol.Chem., 278, 2003
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1LE5
 
 | Crystal structure of a NF-kB heterodimer bound to an IFNb-kB | Descriptor: | 5'-D(*AP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*T)-3', Nuclear factor NF-kappa-B p50 subunit, ... | Authors: | Berkowitz, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G. | Deposit date: | 2002-04-09 | Release date: | 2003-04-15 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The X-ray crystal structure of the
NF-kB p50/p65 heterodimer bound
to the Interferon beta-kB site J.Biol.Chem., 277, 2002
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1LEI
 
 | The kB DNA sequence from the HLV-LTR functions as an allosteric regulator of HIV transcription | Descriptor: | 5'-D(*CP*TP*CP*AP*GP*GP*GP*AP*AP*AP*GP*TP*AP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*5ITP*AP*CP*5ITP*5ITP*5ITP*CP*CP*CP*TP*GP*AP*G)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ... | Authors: | Chen-Park, F, Huang, D.B, Ghosh, G. | Deposit date: | 2002-04-09 | Release date: | 2003-04-15 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The kB DNA sequence from the HIV Long Terminal Repeat functions as an allosteric regulator of HIV transcription J.Biol.Chem., 277, 2002
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4OT9
 
 | crystal structure of the C-terminal domain of p100/NF-kB2 | Descriptor: | Nuclear factor NF-kappa-B p100 subunit, SULFATE ION | Authors: | Tao, Z.H, Huang, D.B, Fusco, A, Gupta, K, Ware, C.F, Duynne, G.V. | Deposit date: | 2014-02-13 | Release date: | 2015-01-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | p100/I kappa B delta sequesters and inhibits NF-kappa B through kappaBsome formation. Proc.Natl.Acad.Sci.USA, 111, 2014
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